Central Nervous System Control of breathing in Natural Conversational Turn-Taking DOI
Camilla Di Pasquasio,

Lila De Pellegrin,

Arthur Pineaud

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 20, 2024

Abstract Discussion is a fundamental social activity requiring coordination of speech between interlocutors. Speech production complex human behaviour that involves several anatomo-physiological processes, including inspiration and expiration. The aim the present study to investigate neurophysiological underpinnings speech-related respiration events in conversational turn-taking. We made use an existing corpus natural conversations participant its interlocutor (Human or Robot) focusing on synchronised (1) behavioural (conversation turn-taking), (2) respiratory (maxima inspiration) (3) (fMRI) data. Precisely timed conversation transcripts from 25 participants were used categorise breathing maxima based their timing relative participant’s onset. In agreement with literature, closest time maximum each turn occurred average 200 ms prior fMRI second-level contrast ( p FWE < 0.05, extend k > 5 cm 3 ) Resp+ (maximum associated speech) versus Resp-, exclusively masked exclude related areas, revealed bilateral activations central sulcus, brainstem cerebellum. cluster comprises pattern generators, possibly preBötzinger complex, need be inhibited enslave not physiological needs, while sulcus likely located postcentral primary sensory cortex receiving upper torso inputs indicating lungs are filled, cerebellum clusters could play role onset, after maximum. These results show how cortical, cerebellar coordinated control during turn-taking part intricate mechanisms contribute communication dynamics.

Language: Английский

The pupillary respiratory‐phase response: pupil size is smallest around inhalation onset and largest during exhalation DOI Creative Commons
Martin Schaefer, Sebastiaan Mathôt, Mikael Lundqvist

et al.

The Journal of Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Abstract Respiration shapes brain activity and synchronizes sensory exploratory motor actions, with some evidence suggesting that it also affects pupil size. However, for a coupling between respiration size remains scarce inconclusive, hindered by small sample sizes limited controls. Given the importance of in visual perception as reflection state, understanding its relationship is essential. In five experiments using pre‐registered protocol, we systematically investigated how respiratory phase across different conditions. Experiment 1 ( n = 50), examined nasal oral breathing at rest under dim lighting nearby fixation points, then replicated these results identical conditions 2 53). 3 112) extended this to active tasks, while 4 57) controlled paces ambient distant fixation. Finally, 5 34), individuals isolated congenital anosmia (born without olfactory bulbs) were used lesion‐type model during visual–auditory tasks assess whether respiratory–pupil link depends on bulb‐driven oscillations. Across all – free breathing; distances; bulbs consistently found smallest around inhalation onset largest exhalation. We term effect pupillary respiratory‐phase response, fourth known mechanism influencing size, alongside light, near psychosensory responses. image Key points The influence dynamics has long been debated. study, changes cycle through series experiments, varying lighting, distance region involvement. show exhalation, dilatation occurring most early constriction primarily latter part This pattern was consistent experimental conditions, demonstrating robust likely brainstem circuits.

Language: Английский

Citations

0
Breath-hold diving as a tool to harness a beneficial increase in cardiac vagal tone DOI
Pierrick Martinez, Mathias Dutschmann,

Vincent Épercieux

et al.

Respiratory Physiology & Neurobiology, Journal Year: 2025, Volume and Issue: unknown, P. 104416 - 104416

Published: March 1, 2025

Language: Английский

Citations

0
Amygdalar involvement in respiratory dysfunction DOI Creative Commons
Pedro Trevizan‐Baú, John A. Hayes, Donald C. Bolser

et al.

Frontiers in Physiology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 28, 2024

The brainstem has long been recognized as the major respiratory control center, but it become increasingly appreciated that areas upstream of modulate respiration and airway defensive behaviors. This review aims to define role amygdala, a key temporal brain region essential for limbic function, in defenses. We summarize literature describing roles amygdala respiration, swallow, cough, smooth muscle contraction, mucus secretion. emphasize need understand how regulates these functions both at local scale network identify knowledge gaps current future investigations. Lastly, we highlight suggesting dysfunction may contribute dysfunction.

Language: Английский

Citations

2
Central Nervous System Control of breathing in Natural Conversational Turn-Taking DOI
Camilla Di Pasquasio,

Lila De Pellegrin,

Arthur Pineaud

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 20, 2024

Abstract Discussion is a fundamental social activity requiring coordination of speech between interlocutors. Speech production complex human behaviour that involves several anatomo-physiological processes, including inspiration and expiration. The aim the present study to investigate neurophysiological underpinnings speech-related respiration events in conversational turn-taking. We made use an existing corpus natural conversations participant its interlocutor (Human or Robot) focusing on synchronised (1) behavioural (conversation turn-taking), (2) respiratory (maxima inspiration) (3) (fMRI) data. Precisely timed conversation transcripts from 25 participants were used categorise breathing maxima based their timing relative participant’s onset. In agreement with literature, closest time maximum each turn occurred average 200 ms prior fMRI second-level contrast ( p FWE < 0.05, extend k > 5 cm 3 ) Resp+ (maximum associated speech) versus Resp-, exclusively masked exclude related areas, revealed bilateral activations central sulcus, brainstem cerebellum. cluster comprises pattern generators, possibly preBötzinger complex, need be inhibited enslave not physiological needs, while sulcus likely located postcentral primary sensory cortex receiving upper torso inputs indicating lungs are filled, cerebellum clusters could play role onset, after maximum. These results show how cortical, cerebellar coordinated control during turn-taking part intricate mechanisms contribute communication dynamics.

Language: Английский

Citations

0