Efficacy and cerebral mechanisms of acupuncture for chronic obstructive pulmonary disease: study protocol for a multicenter, randomized controlled neuroimaging trial DOI Creative Commons

Xugui Chen,

Chan Xiong,

Wei Xiao

et al.

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: June 26, 2024

Introduction Although acupuncture is recommended by chronic obstructive pulmonary disease (COPD) treatment guidelines owing to its effects on dyspnea, the underlying neurobiological mechanisms of these remain unclear. This study aims evaluate efficacy in patients with stable COPD and explore possible involvement specific brain regions. Methods a prospective, multicenter, single-blind, randomized controlled trial. A total 90 participants will be recruited from three centers randomly assigned 1:1 ratio undergo at acupoints disease-affected meridian (DAM) or non-acupoints non-affected (NAM), addition routine pharmacological treatments. All 30 min times week for 8 weeks followed up 12 months. The primary outcome severity as measured using Borg Dyspnea Scale visual analog scale rest after exercise. secondary outcomes include multidimensional profile dyspnea Dyspnea-12, modified Medical Research Council Scale, assessment test; quality life assessments St George's Respiratory Questionnaire Hospital Anxiety Depression Scale; additional measurements exacerbation frequency, function, 6-min walking distance. Magnetic resonance imaging (MRI) performed before exercise potential exertional dyspnea. depression analyzed their correlation activation areas involved Discussion trial use evaluation relieving terms emotion an perspective. It expected provide strong evidence support those aother diseases involving Additionally, it provides novel insights into central intervention Trial registration Chinese Clinical Registry ( https://www.chictr.org.cn/ ): ChiCTR2300071725.

Language: Английский

Network analysis of depression and anxiety symptoms in Chinese rheumatoid arthritis patients DOI Creative Commons
Lijuan Zhang, Weiyi Zhu, Beiwen Wu

et al.

PeerJ, Journal Year: 2023, Volume and Issue: 11, P. e16356 - e16356

Published: Nov. 6, 2023

Rheumatoid arthritis (RA) patients are susceptible to comorbid anxiety and depression. From the network model perspective, comorbidity is due direct interactions between depression symptoms. The objective of this study was assess structure symptoms in Chinese RA identify central bridge as well how related quality life (QoL) network.A total 402 were included study. Depression measured by Hospital Anxiety Scale (HADS). R software used estimate network. Specifically, we computed predictability, expected influence (EI) (BEI) for each symptom showed a flow "QoL".Our revealed that strongest edge D2 "See bad side things" D3 "Not feeling cheerful" across whole For centrality indices, D6 "Feeling down" had highest EI values network, while A4 "Trouble relaxing" BEI their respective community. As "QoL", it A1 "Nervousness"."Feeling emerged symptoms, anxiety-depression patients. Intervention on nurses should prioritize these

Language: Английский

Citations

3
Flourishing despite Chronic Obstructive Pulmonary Disease (COPD): Findings from a Nationally Representative Survey of Canadians Aged 50 and Older DOI Open Access
Sally Abudiab, Esme Fuller‐Thomson

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(23), P. 16337 - 16337

Published: Dec. 6, 2022

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and often associated with serious disability depression. Little known about the characteristics those who are in complete mental health (CMH) despite having COPD. This study’s objectives to: (1) estimate prevalence odds absence psychiatric disorders (APD) CMH among older adults that reported COPD, compared to their peers did not; (2) identify factors APD CMH. Bivariate logistic regression analyses were conducted using nationally representative Canadian Community Health Survey—Mental Health. The results indicate there was significantly (p < 0.001) lower (86.7% vs. 95.0%) (66.7% 77.0%) aged 50+ COPD (n = 703) without 10,189). Half sample female (50.5%) majority whom under age 70 (62.5%). Factors 0.05) higher include being married, confidant, physically active, no lifetime history major depressive disorder or generalized anxiety disorder. For every additional adverse childhood experience, declined by 31%. mentally flourishing this disabling life-threatening These findings underline importance targeted interventions outreach most vulnerable poorer outcomes including socially isolated.

Language: Английский

Citations

4
Feature aggregation-based multi-relational knowledge reasoning for COPD intelligent diagnosis DOI
Xiaolian Yang, Yin Zhang⋆, Fang Hu

et al.

Computers & Electrical Engineering, Journal Year: 2024, Volume and Issue: 114, P. 109068 - 109068

Published: Jan. 9, 2024

Language: Английский

Citations

0
Research progress on the pathogenesis of chest tightness variant asthma characterized by chest tightness DOI Open Access

Luanqing Che,

Jianxing Lai,

Huaqiong Huang

et al.

Journal of Zhejiang University (Medical Sciences), Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 1, 2024

Chest tightness variant asthma (CTVA) is an atypical form of with chest as the sole or predominant symptom. The underlying receptors for may be bronchial C-fibers rapidly adapting receptors. nerve impulses are transmitted via vagus and processed in different regions cerebral cortex. associated sensory perception, CTVA patients have a heightened ability to detect subtle changes lung function, which unrelated respiratory muscle activity, hyperinflation, mechanical loading system. airway inflammation, pulmonary ventilation dysfunction (especially involving small airways), hyperresponsiveness underlie sensation tightness. prone comorbid anxiety depression, share similar central nervous system processing pathways dyspnea, suggesting possible neurological basis development CTVA. This article examines recognition mechanisms symptoms, explores pathogenesis CTVA, focusing on its association dysfunction, hyperresponsiveness, psychosocial factors.

Language: Английский

Citations

0
Efficacy and cerebral mechanisms of acupuncture for chronic obstructive pulmonary disease: study protocol for a multicenter, randomized controlled neuroimaging trial DOI Creative Commons

Xugui Chen,

Chan Xiong,

Wei Xiao

et al.

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: June 26, 2024

Introduction Although acupuncture is recommended by chronic obstructive pulmonary disease (COPD) treatment guidelines owing to its effects on dyspnea, the underlying neurobiological mechanisms of these remain unclear. This study aims evaluate efficacy in patients with stable COPD and explore possible involvement specific brain regions. Methods a prospective, multicenter, single-blind, randomized controlled trial. A total 90 participants will be recruited from three centers randomly assigned 1:1 ratio undergo at acupoints disease-affected meridian (DAM) or non-acupoints non-affected (NAM), addition routine pharmacological treatments. All 30 min times week for 8 weeks followed up 12 months. The primary outcome severity as measured using Borg Dyspnea Scale visual analog scale rest after exercise. secondary outcomes include multidimensional profile dyspnea Dyspnea-12, modified Medical Research Council Scale, assessment test; quality life assessments St George's Respiratory Questionnaire Hospital Anxiety Depression Scale; additional measurements exacerbation frequency, function, 6-min walking distance. Magnetic resonance imaging (MRI) performed before exercise potential exertional dyspnea. depression analyzed their correlation activation areas involved Discussion trial use evaluation relieving terms emotion an perspective. It expected provide strong evidence support those aother diseases involving Additionally, it provides novel insights into central intervention Trial registration Chinese Clinical Registry ( https://www.chictr.org.cn/ ): ChiCTR2300071725.

Language: Английский

Citations

0