Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: May 16, 2023
Abstract
Microalgae
are
a
natural
source
of
valuable
compounds
with
wide
range
applications.
Given
their
physiological
plasticity,
strategies
aiming
at
increasing
the
content
biomolecules
have
been
proposed.
In
this
study,
low-dose
copper
and
blue/red
lights
were
combined
used
as
manipulative
strategy
to
induce
biomolecule
accumulation
in
Kirchneriella
contorta
(Schmidle).
Cultures
exposed
1.6x10
−
9
1.7x10
8
mol
L
1
free
(Cu
2+
)
concentration
under
white
light
for
48
h.
Afterwards,
was
replaced
blue
or
red
up
96
We
evaluated
population
growth
through
rates,
photosynthesis
pulse
amplitude
modulated
fluorescence
(PAM)
by
quantifying
chlorophyll
,
carotenoids,
carbohydrates
proteins.
The
results
showed
that
3.8x10
Cu
light,
2x
more
4x
3x
extra
proteins
accumulated
cells
compared
control.
Among
colors,
most
significantly
interfered
alga
metabolism
other
colors.
Although
rates
quantum
yields
not
affected,
non-photochemical
quenching
(NPQ)
increased
showing
its
higher
energy
may
impacted
photosynthetic
apparatus.
This
study
contributes
biotechnology
microalgae
proposing
triggered
build-up
K.
contorta.
Soil & Environmental Health,
Journal Year:
2023,
Volume and Issue:
1(1), P. 100003 - 100003
Published: Feb. 3, 2023
Hormesis
refers
to
positive
biological
effects
caused
by
exposure
low
doses
of
a
stressor
known
be
toxic
at
higher
doses.
These
include
an
enhanced
defense
system
and
stimulated
plant/microorganism
growth
reproduction.
has
emerged
as
fundamental
concept
with
broad
relevance
the
field
soil
environmental
health.
Its
utilization
in
evaluating
ecotoxicity
can
reduce
uncertainties
introduced
extrapolating
from
high
pollutants.
Similarly,
its
consideration
risk
assessment
help
tackle
toxicity
risks
imposed
chemical
mixtures.
Further,
it
maximize
effectiveness
novel
agrochemicals
applied
lowest
possible
concentration,
thus
reducing
their
ecological
human
risks.
Hormesis-based
interventions,
such
plant
priming
stimulation
beneficial
insects
waste-degrading
microbes,
further
agrochemical
loads
into
environment,
thereby
enhancing
Inclusion
hormesis
strategies
control
harmful
organisms,
pests,
pathogenic
microbes
algal
bloom
aid
combating
resistance.
Hormesis-inclusive
studies
also
provide
useful
information
regarding
suitable
pollutant
tolerance
levels
for
microorganisms
plants
during
bioremediation
phytoremediation,
remediation.
In
sum,
is
highly
relevant
offers
numerous
potential
applications
health
research.
Ecotoxicology and Environmental Safety,
Journal Year:
2023,
Volume and Issue:
257, P. 114929 - 114929
Published: April 20, 2023
The
ecological
effects
of
antibiotics
in
surface
water
have
attracted
increasing
research
attention.
In
this
study,
we
investigated
the
combined
ecotoxicity
erythromycin
(ERY)
and
roxithromycin
(ROX)
on
microalgae,
Chlorella
pyrenoidosa,
removal
ERY
ROX
during
exposure.
calculated
96-h
median
effect
concentration
(EC50)
values
ERY,
ROX,
their
mixture
(2:1
w/w)
were
7.37,
3.54,
7.91
mg∙L-1,
respectively.
However,
predicted
EC50
ERY+ROX
5.42
1.51
based
addition
independent
action
models,
This
demonstrated
toxicity
ERY+
showed
an
antagonistic
pyrenoidosa.
During
14-d
culture,
low-concentration
(EC10)
treatments
with
caused
growth
inhibition
rate
to
decrease
first
12
d
increase
slightly
at
14
d.
contrast,
high-concentration
significantly
inhibited
microalgae
(p
<
0.05).
Changes
total
chlorophyll
contents,
SOD
CAT
activities,
MDA
contents
suggested
that
individual
induced
higher
oxidative
stress
than
treatments.
After
culture
time,
residual
Ery
low
high
17.75%
74.43%,
Rox
76.54%
87.99%,
but
residuals
8.03%
73.53%
treatment.
These
indicated
antibiotic
efficiency
was
treatments,
especially
concentrations
(EC10).
Correlation
analysis
there
a
significant
negative
correlation
between
C.
pyrenoidosa
activity
content,
enhanced
ability
benefited
from
increased
cell
content.
Findings
study
contribute
predicting
risk
coexisting
aquatic
environment,
improving
biological
treatment
technology
wastewater.
Plants,
Journal Year:
2024,
Volume and Issue:
13(3), P. 354 - 354
Published: Jan. 25, 2024
Erythromycin,
a
macrolide
antibiotic,
is
prioritized
pollutant
that
poses
high
risk
to
environmental
health.
It
has
been
detected
in
different
matrices
and
can
cause
undesired
effects
aquatic
organisms,
particularly
freshwater
algae,
which
are
primary
producers.
However,
the
impact
of
erythromycin
on
marine
algae
remains
largely
unexplored.
Erythromycin
reported
induce
hormetic
diatom
Thalassiosira
weissflogii
(T.
weissflogii).
These
associated
with
molecular
pathways
biological
processes
ribosome
assembly,
protein
translation,
photosynthesis,
oxidative
stress.
alterations
global
gene
expression
have
yet
be
validated
at
metabolic
level.
The
present
study
used
non-targeted
metabolomic
analysis
reveal
altered
profiles
T.
under
results
showed
increased
cell
density
was
possibly
attributed
accumulation
steroidal
compounds
potential
hormonic
action
Additionally,
slight
increases
mitochondrial
membrane
(MMP)
viable
cells
were
observed
treatment
0.001
mg/L
(an
environmentally
realistic
level).
Contrarily,
0.75
2.5
treatments
(corresponding
EC20
EC50,
respectively)
decreases
MMP,
density,
algal
cells,
modified
involving
ATP-binding
cassette
(ABC)
transporters,
metabolism
hydrocarbons
lipids,
thiamine
metabolism,
porphyrin
chlorophyll.
findings
suggest
analysis,
as
complement
measurement
apical
endpoints,
could
provide
novel
insights
into
mechanisms
hormesis
induced
by
antibiotic
agents
algae.
