Development of a Molecular Beacon-Based Genosensor for Detection of Human Rotavirus A DOI
Pooja Rani Kuri, Pranab Goswami

Molecular Biotechnology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 31, 2024

Language: Английский

AuNP decorated aegle marmelos leaf as SERS substrate for trace detection of antibiotics and machine learning based classification DOI Open Access
Dipjyoti Sarma,

Macduf R Marak,

Indrani Chetia

et al.

Physica Scripta, Journal Year: 2024, Volume and Issue: 99(2), P. 026006 - 026006

Published: Jan. 9, 2024

Abstract Surface-enhanced Raman spectroscopy (SERS) has emerged as a reliable molecular spectroscopic technique for trace detection of chemical and biological samples. Present study illustrates new SERS platform which been obtained through surface adsorption gold nanoparticles (AuNP) on microscopically roughened aegle marmelos ( AM ) leaf. The micro-structured patterns the leaves promote generation hotspot regions deposited AuNPs thus, aids in electromagnetic enhancement scattered signals from sample. For proposed platform, with rhodamine6G (R6G) an analyte, limit (LoD) was found to be 0.88 nM. applicability designed realized quantification two commonly used antibiotics- Ceftriaxone (CEFTR) Ceftiofur sodium (CEF-Na) residues cow milk Furthermore, dimensionality reduction method known principal component analysis (PCA) optimal machine learning-based model were built categorize analytes suggested learning model’s classification accuracy 94%.

Language: Английский

Citations

6
Recent advances in the design of SERS substrates and sensing systems for (bio)sensing applications: Systems from single cell to single molecule detection DOI Creative Commons
Sai Ratnakar Tadi,

Ashwini G Shenoy,

Anirudh Bharadwaj

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 13, P. 670 - 670

Published: March 18, 2025

The Raman effect originates from spontaneous inelastic scattering of photons by matter. These provide a characteristic fingerprint this matter, and are extensively utilized for chemical biological sensing. inherently lower generation these scattered photons, do not hold potential their direct use in sensing applications. Surface enhanced spectroscopy (SERS) overcomes the low sensitivity associated with assists diverse analytes, including ions, small molecules, inorganics, organics, radionucleotides, cells. Plasmonic nanoparticles exhibit localized surface plasmon resonance (LSPR) when they closely spaced, create hotspots where electromagnetic field is significantly enhanced. This amplifies signal may offer up to 10 14-fold SERS enhancement. development active substrates requires further consideration optimization several critical features such as periodicity, hotspot density, mitigation sample or autofluorescence, tuning hydrophilicities, specific (bio) recognition elements suitable linkers bioconjugation chemistries, appropriate optics obtain relevant outcomes terms sensitivity, cross-sensitivity, limit detection, signal-to-noise ratio (SNR), stability, shelf-life, disposability. article comprehensively reviews recent advancements on disposable materials commercial grades paper, textiles, glasses, polymers, some blue-ray digital versatile discs (DVDs) SERS-active point-of-use (POU) technologies have been reviewed critiqued analyte detection resource-limited settings, highlighting prospects applications ranging single-molecule single-cell detection. We conclude possible avenues developing viable deployable sensors holding immense environmental monitoring, food safety biomedical diagnostics.

Language: Английский

Citations

0
The application of the paper-based optical chemosensors DOI
Wei Liu,

Xiaohu Ma,

Peiyu Jiang

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 355 - 407

Published: Jan. 1, 2025

Language: Английский

Citations

0
Electrochemically deposited bimetallic SERS substrate for trace sensing of antibiotics DOI
Dipjyoti Sarma,

Ankush Medhi,

Dambarudhar Mohanta

et al.

Microchimica Acta, Journal Year: 2023, Volume and Issue: 191(1)

Published: Dec. 13, 2023

Language: Английский

Citations

9
Challenges and development strategies of conjugated polymers composites-based biosensors for detection of virus biomarkers DOI
Vinh Van Tran, Vu Khac Hoang Bui, Dang Le Tri Nguyen

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 503, P. 158532 - 158532

Published: Dec. 11, 2024

Language: Английский

Citations

2
Aptamer SERS and RRS determination of trace lead ions using nitrogen-doped carbon dot to catalyze the new nano-gold reaction DOI
Hui Li,

Caina Jiang,

Xuedan He

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2023, Volume and Issue: 303, P. 123146 - 123146

Published: July 13, 2023

Language: Английский

Citations

6
Plasma treated bimetallic nanofibers as sensitive SERS platform and deep learning model for detection and classification of antibiotics DOI
Dipjyoti Sarma, Kaushik K. Nath, Sritam Biswas

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 327, P. 125417 - 125417

Published: Nov. 10, 2024

Language: Английский

Citations

0
Development of a Molecular Beacon-Based Genosensor for Detection of Human Rotavirus A DOI
Pooja Rani Kuri, Pranab Goswami

Molecular Biotechnology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 31, 2024

Language: Английский

Citations

0