In vitro anticancer effects in hepatocellular carcinoma (HCC) and protein interaction study of xanthoangelol DOI

Qiaobei Li,

Zhe Lou,

Chunyan Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138530 - 138530

Published: Dec. 1, 2024

Language: Английский

The binding interaction of chlormadinone acetate with human alpha-2-macroglobulin: Multi-spectroscopic and calorimetric investigation DOI
Mohammad Khalid Zia, Tooba Siddiqui, Mohammad Muaz

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141541 - 141541

Published: Jan. 1, 2025

Language: Английский

Citations

0
Biological evaluation of sophoridine by interaction with plasma transport protein and protective effects in cardiomyocytes DOI Creative Commons

Zheng Wu,

Shujuan Cheng,

Shaoping Wang

et al.

Arabian Journal of Chemistry, Journal Year: 2024, Volume and Issue: 17(12), P. 106014 - 106014

Published: Oct. 9, 2024

Language: Английский

Citations

1
Revealing the synergistic antibacterial mechanisms of resveratrol (RES) and pulsed electric field (PEF) against Acetobacter sp DOI
Debao Niu,

Xiaoqin Feng,

Ailin Zhang

et al.

Food Research International, Journal Year: 2024, Volume and Issue: 197, P. 115237 - 115237

Published: Oct. 23, 2024

Language: Английский

Citations

1
Gamma globulin binding of hinokiflavone with anti-osteoporosis effects: A mechanistic study DOI Creative Commons
Zhen Zhang,

Jialang Zhang,

Baorong He

et al.

Arabian Journal of Chemistry, Journal Year: 2024, Volume and Issue: 17(6), P. 105747 - 105747

Published: March 22, 2024

Oxidative stress can trigger apoptosis and associated reduction of osteoblast activity. Hinokiflavone (HNK) with a biflavonoid-based structure might show potent antioxidant However, before the application this compound as promising therapeutic bioactive material, its interaction blood proteins should be investigated to further reveal pharmacokinetic pharmacodynamic properties. Therefore, in paper, HNK γ-globulin, one main proteins, was assessed. Then, properties against H2O2-induced cytotoxicity MC3T3-E1 cells were It shown that potentially bind γ-globulin mostly aid hydrophilic forces, slight effect on protein structure. then determined significantly recovered cell survival alkaline phosphatase (ALP) activity collagen-I content exposed H2O2. In addition, decreased production intracellular reactive oxygen species (ROS) malondialdehyde (MDA) triggered by Finally, control induction H2O2 mediated regulation Bax, Bcl-2 caspase-3. Taken together, these data demonstrated binding significant protective effects inhibition dysfunction, oxidative stress, apoptosis.

Language: Английский

Citations

0
Elucidating the Binding Interaction of a Highly Efficient Phytochemical-Sinapic Acid with Human Serum Albumin: A Spectroscopic and Calorimetric Approach DOI
Tooba Siddiqui, Humaira Rizwana, Iram Siddique

et al.

Journal of Macromolecular Science Part B, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 16

Published: Sept. 11, 2024

Language: Английский

Citations

0
In vitro anticancer effects in hepatocellular carcinoma (HCC) and protein interaction study of xanthoangelol DOI

Qiaobei Li,

Zhe Lou,

Chunyan Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138530 - 138530

Published: Dec. 1, 2024

Language: Английский

Citations

0