Vitamin B₆ Cofactor–Derived AIEE Active Luminogen for Detecting Ciprofloxacin and Levofloxacin

Luminescence, Journal Year: 2025, Volume and Issue: 40(4)

Published: April 1, 2025

The present study reports an aggregation-induced emission enhancement (AIEE) luminogen (AIEEgen) NPL derived by condensing equimolar amount of vitamin B6 cofactor pyridoxal 5'-phosphate (PLP) and 3-hydroxy-2-naphthohydrazide. AIEE characteristics was explored in mixed DMSO-HEPES buffer (pH 7.4, 10 mM) medium. weakly yellow emissive DMSO turns to cyan as the fractions HEPES (fHEPES) increased from 10% 95% DMSO. results dynamic light scattering (DLS) scanning electron microscope (SEM) analysis supported formation self-aggregates NPL. When fluorescence spectral changes AIEEgen (fHEPES 95%, λex = 370 nm, λem 485 nm) were examined adding different drugs, presence ciprofloxacin levofloxacin intensity found UV-Vis absorption, DLS, zeta potential SEM new complex species between selective drugs. detection limits for estimated low 2.84 0.21 μM, respectively. Additionally, analytical usefulness investigated quantifying real human blood serum.

Language: Английский

Portable arginine sensing on polyvinyl alcohol membrane based on aggregation-induced emission enhancement of carbon dots

Talanta, Journal Year: 2025, Volume and Issue: unknown, P. 128177 - 128177

Published: April 1, 2025

Language: Английский