Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(44), P. 30615 - 30625
Published: Oct. 29, 2024
The
direct
utilization
of
carbon
dioxide
as
an
ideal
one-carbon
source
in
value-added
chemical
synthesis
has
garnered
significant
attention
from
the
standpoint
global
sustainability.
In
this
regard,
photo/electrochemical
reduction
CO
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 1, 2025
Aryl
chlorides
are
more
commercially
available
and
lower
cost
compared
with
aryl
bromides
iodides.
However,
the
use
of
(hetero)aryl
as
radical
precursors
for
di(hetero)arylation
alkenes
remains
an
underdeveloped
area.
Furthermore,
existing
examples
theses
reactions
predominantly
confined
to
activated
alkenes.
In
this
study,
we
introduce
a
photoirradiation-promoted
benzophenone-catalyzed
1,2-di(hetero)arylation
process
that
is
applicable
both
unactivated
alkenes,
utilizing
cyanoarenes
sources.
Importantly,
method
allows
simultaneous
introduction
two
heterocycles
high
regioselectivity.
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 29, 2025
Simultaneous
construction
of
two
new
C-C
bonds
in
the
alkene
substrates
regioselectively
is
significantly
challenging.
Herein,
we
report
an
unprecedented
regioselective
arylcarboxylation
strategy
activated
alkenes
with
readily
available
aryl
halides
and
tetrabutylammonium
oxalate
as
reductant
C1
source
under
visible-light-induced
conditions.
The
reaction
proceeds
smoothly
to
access
various
carboxylic
acids
absence
any
catalysts,
additives,
metal
promoters,
or
pre-established
CO2
atmosphere.
electron
donor-acceptor
(EDA)
complex
formed
between
stoichiometric
amounts
trigger
single-electron
reduction
relay
process
after
irradiation
visible
light.
situ
generated
oxalic
radical
anion
species
undergoes
homolysis
bond
releases
potent
source,
respectively,
facilitate
reductive
carboxylation.
Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
42(11), P. 1203 - 1208
Published: Feb. 6, 2024
Comprehensive
Summary
Herein,
we
report
an
efficient
and
practical
protocol
for
the
photoinduced
dehalocyclization
of
ortho
‐halophenylacrylamides
with
formate
by
engagement
a
CO
2
radical
anion
to
access
substituted
oxindoles.
This
method
proceeds
smoothly
under
mild
conditions
exhibits
wide
range
substrate
as
well
remarkable
functional
group
compatibility.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(44), P. 30615 - 30625
Published: Oct. 29, 2024
The
direct
utilization
of
carbon
dioxide
as
an
ideal
one-carbon
source
in
value-added
chemical
synthesis
has
garnered
significant
attention
from
the
standpoint
global
sustainability.
In
this
regard,
photo/electrochemical
reduction
CO