TrAC Trends in Analytical Chemistry,
Journal Year:
2018,
Volume and Issue:
102, P. 343 - 358
Published: March 8, 2018
The
European
Commission
Implementing
Decision
EU
2015/495
included
three
steroidal
estrogens,
namely
17α-ethinyl
estradiol,
17β-estradiol,
and
estrone,
in
the
so-called
"watch
list"
of
Water
Framework
Directive
(WFD).
monitoring
these
compounds
is
difficult
because
detection
limits
majority
available
analytical
methods
cannot
achieve
very
low
target
concentrations
required
to
meet
proposed
environmental
quality
criteria.
In
2014,
a
combined
Science-Policy
Interface/Chemical
Monitoring
Emerging
Pollutants
project
was
launched
this
challenge.
involved
24
research
organizations
agencies
from
12
different
countries.
Sixteen
surface
water
(SW)
17
wastewater
(WW)
samples
were
collected
across
Europe
analysed
using
five
vitro
effect-based
chemical
methods.
A
general
description
data
evaluation
provided
by
Könemann
colleagues
companion
publication
2018.
our
study,
we
compared
bioanalytical
results
with
regard
their
application
for
aquatic
status
assessment.
Therefore
considered
potential
predict
population-relevant
risks
organisms
specificity
sensitivity
various
used
both
approaches.
Finally,
tested
discussed
applicability
relevance
previously
suggested
trigger
values
(EBT).
Results
risk
assessment
based
on
correlated
highly
estrogenic
activities
(expressed
as
17β-estradiol
equivalents
(EEQ)
determined
methods),
demonstrating
ability
bioassays
mixture
caused
estrogens.
For
about
15%
SW
40%
WW
chemical-analytical
too
high
allow
assessment,
while
all
below
EBT.
This
demonstrates
that
are
suitable
waters.
quite
specific
estrogens
sensitive,
meaning
they
have
probability
detect
false
positive
or
negative
results.
After
testing
alternative
EBT
proposals,
concluded
use
preliminary
400
pg/L
EEQ
screening
corresponding
AA-EQS
E2.
Further
test
refinements
value
not
excluded.
We
conclude
can
progress
purely
approach
monitoring,
single
substance
known
unknown
Despite
few
limitations,
recommendable
under
WFD
they,
a)
able
sensitively
quantify
activity
samples,
b)
effect
estrogen
mixtures
including
chemicals
receptor
activating
properties,
c)
an
ecotoxicological
calculate
quotients.
similar
ratio
regulatory
assessments,
but
allows
integrated
study
support
introduction
holistic
regulation
environment
WFD,
recently
Directors.
An
one
most
relevant
modes
action
endocrine
disruption
will
authorities
responsible
focus
resources
improve
ecological
waterbodies.
The Science of The Total Environment,
Journal Year:
2020,
Volume and Issue:
748, P. 141362 - 141362
Published: July 31, 2020
COVID-19
pandemic
is
on
a
trajectory
to
cause
catastrophic
global
upheaval
with
the
potential
alter
geopolitical
and
socio-economic
norms.
Many
countries
are
frantically
responding
staggering
financial
stimulus
recovery
initiatives.
This
opinion-paper
reviews
challenges,
opportunities,
solutions
for
post-COVID-19
era
that
focuses
intensive
sustaining
of
agri-food
supply
chain
in
tandem
meeting
high
demand
new
green
deal
innovation.
For
example,
development
wet
peatland
innovation,
known
as
Paludiculture,
can
intensively
sustain
blend
innovations
will
help
support
transitioning.
The
future
looks
bright
creation
sustainability
multi-actor
innovation
hubs
support,
connect,
enable
businesses
recover
pivot
beyond
pandemic.
nexus
between
first
'Green
Deal'
initiative
supporting
64
selected
European
Startups
SMEs
(European
Innovation
Council)
43
Irish
Disruptive
Technology
projects
addressed
context
cross-cutting
developments
relevance
COVID-19.
Candidate
areas
consideration
focus
climate
action,
digitization,
manufacturing,
sustainable
food
production,
security,
waste
mitigation.
Recommendations
also
provided
facilitate
community
transitioning,
training,
enterprise,
employment
low
carbon
economy.
The Science of The Total Environment,
Journal Year:
2020,
Volume and Issue:
752, P. 142259 - 142259
Published: Sept. 10, 2020
Currently,
there
is
no
effective
vaccine
for
tackling
the
ongoing
COVID-19
pandemic
caused
by
SARS-CoV-2
with
occurrence
of
repeat
waves
infection
frequently
stretching
hospital
resources
beyond
capacity.
Disease
countermeasures
rely
upon
preventing
person-to-person
transmission
SARS-CoV2
so
as
to
protect
front-line
healthcare
workers
(HCWs).
brings
enormous
challenges
in
terms
sustaining
supply
chain
single-use-plastic
personal
and
protective
equipment
(PPE).
Post-COVID-19,
changes
medical
practice
will
drive
high
demand
PPE.
Important
include
mitigating
potential
risk
aerosol
setting
using
PPE
(such
filtering
facepiece
respirators
(FFRs))
appropriate
use
face
coverings
general
public
that
carries
a
lower
risk.
reuse
short
term
solution
during
where
increased
evidence
deployment
reprocessing
methods
such
vaporized
hydrogen
peroxide
(30
35%
VH2O2)
used
alone
or
combined
ozone,
ultraviolet
light
at
254
nm
(2000
mJ/cm2)
moist
heat
(60
°C
humidity
60
min).
Barriers
potentially
trust
acceptance
HCWs.
Efficacy
are
influenced
wearing
cover
nose
mouth,
type
material
used,
number
layers,
duration
wearing,
superior
ties
over
ear
loops.
Insertion
clip
into
cloth
may
help
maintaining
fit.
Use
min
as,
domestic
washing
machine
spin
dryer)
has
been
advocated
covering
decontamination.
Risk
virus
infiltration
improvised
due
humidity,
liquid
diffusion
retention.
Future
sustained
be
availability
recyclable
innovative
biomedical
waste
management.