SSRN Electronic Journal,
Journal Year:
2021,
Volume and Issue:
unknown
Published: Jan. 1, 2021
Globally,
amphibian
species
are
experiencing
dramatic
population
declines,
and
many
face
the
risk
of
imminent
extinction.
A
number
different
drivers
for
this
loss
have
been
identified,
including
habitat
degradation,
climate
change,
chytridiomycosis.
More
recently,
endocrine-disrupting
chemicals
(EDCs)
recognised
as
an
underappreciated
factor
contributing
to
global
declines.
In
regard,
use
hormonal
growth
promotants
in
livestock
industry
provides
a
direct
pathway
EDCs
enter
environment—including
potent
anabolic
steroid
17β-trenbolone.
Emerging
evidence
non-target
suggest
that
17β-trenbolone
can
impact
traits
related
metabolism,
somatic
growth,
sexual
development,
behaviour.
However,
far
less
is
known
about
possible
effects
on
anuran
species,
particularly
impacts
during
early
tadpole
life
stages.
Accordingly,
present
study
we
investigated
28-day
exposure
environmentally
relevant
levels
(mean
measured
concentrations:
10
66
ng/L)
body
size,
condition,
metabolic
rate,
anxiety-related
behaviour
tadpoles
(Limnodynastes
tasmaniensis).
Counter
our
predictions
based
observed
other
taxa,
detected
no
effect
or
tadpoles;
although,
did
detect
subtle,
but
statistically
significant
decrease
condition
at
highest
concentration.
We
hypothesize
may
induce
taxa-specific
function,
behaviour,
with
anurans
being
sensitive
disruption
than
fish,
encourage
further
cross-taxa
investigation
test
hypothesis.
Ecotoxicology and Environmental Safety,
Journal Year:
2021,
Volume and Issue:
224, P. 112698 - 112698
Published: Aug. 25, 2021
In
vivo
testing
systems
for
environmental
androgens
are
scarce.
The
aim
of
this
study
was
to
evaluate
the
potential
male-specific
brightened
body
coloration
in
female
guppies
(Poecilia
reticulata)
serve
as
an
biomarker
using
17β-trenbolone
example.
high
bioaccumulation
skin
suggests
that
it
is
a
target
tissue
androgens.
index,
pigment
cell
ultrastructure,
levels,
sexual
attractiveness,
and
reproductive
capability
were
analyzed
following
28
days
exposure
20
ng/L,
200
2000
ng/L
17β-trenbolone.
Increases
index
caused
by
attributable
increased
pteridine
melanin
levels.
Decreases
number
offspring,
survival
rate
offspring
suggested
changes
translated
into
adverse
outcomes.
Finally,
mRNA
sequencing
indicated
levels
activating
genomic
effects
androgen
receptor
on
xanthine
dehydrogenase
exerting
non-genomic
targeting
microphthalmia-associated
transcription
factor,
tyrosinase,
tyrosinase-related
protein
1
mediated
mitogen-activated
kinase
calcium
signaling
pathways.
We
have
derived
robust
outcome
pathway
androgens,
our
findings
suggest
indicators
at
different
biological
related
can
less-invasive
or
noninvasive
biomarkers
short-term
The Science of The Total Environment,
Journal Year:
2021,
Volume and Issue:
790, P. 148028 - 148028
Published: May 26, 2021
It
is
now
well-established
that
reproduction
in
wildlife
can
be
disrupted
by
anthropogenic
environmental
changes,
such
as
chemical
pollution.
However,
very
little
known
about
how
these
pollutants
might
affect
the
interplay
between
pre-
and
post-copulatory
mechanisms
of
sexual
selection.
Here,
we
investigated
impacts
21-day
exposure
male
eastern
mosquitofish
(Gambusia
holbrooki)
to
a
field-realistic
level
(average
measured
concentration:
11
ng/L)
endocrine-disrupting
17β-trenbolone
(17β-TB)
on
reproductive
traits.
We
examined
behaviour
testing
time
spent
near
female
behind
partition,
well
number
copulation
attempts
made,
chasing
free-swimming
context.
Sperm
traits
were
also
assayed
for
all
males.
found
fish
17β-TB
altered
relationship
key
Furthermore,
17β-TB-exposed
males
had,
average,
higher
percentage
motile
sperm,
performed
fewer
than
unexposed
there
was
no
overall
effect
either
associating
with
or
females.
Taken
together,
our
findings
demonstrate
potential
both
traits,
selection
contaminated
wildlife.
SSRN Electronic Journal,
Journal Year:
2021,
Volume and Issue:
unknown
Published: Jan. 1, 2021
Globally,
amphibian
species
are
experiencing
dramatic
population
declines,
and
many
face
the
risk
of
imminent
extinction.
A
number
different
drivers
for
this
loss
have
been
identified,
including
habitat
degradation,
climate
change,
chytridiomycosis.
More
recently,
endocrine-disrupting
chemicals
(EDCs)
recognised
as
an
underappreciated
factor
contributing
to
global
declines.
In
regard,
use
hormonal
growth
promotants
in
livestock
industry
provides
a
direct
pathway
EDCs
enter
environment—including
potent
anabolic
steroid
17β-trenbolone.
Emerging
evidence
non-target
suggest
that
17β-trenbolone
can
impact
traits
related
metabolism,
somatic
growth,
sexual
development,
behaviour.
However,
far
less
is
known
about
possible
effects
on
anuran
species,
particularly
impacts
during
early
tadpole
life
stages.
Accordingly,
present
study
we
investigated
28-day
exposure
environmentally
relevant
levels
(mean
measured
concentrations:
10
66
ng/L)
body
size,
condition,
metabolic
rate,
anxiety-related
behaviour
tadpoles
(Limnodynastes
tasmaniensis).
Counter
our
predictions
based
observed
other
taxa,
detected
no
effect
or
tadpoles;
although,
did
detect
subtle,
but
statistically
significant
decrease
condition
at
highest
concentration.
We
hypothesize
may
induce
taxa-specific
function,
behaviour,
with
anurans
being
sensitive
disruption
than
fish,
encourage
further
cross-taxa
investigation
test
hypothesis.
