Identifying Transcriptomic Indicators of Tertiary Treated Municipal Effluent in Longnose Dace (Rhinichthys Cataractae) Caged Under Semi-Controlled Conditions in Experimental Raceways DOI
Patricija Marjan, Christopher J. Martyniuk, Maricor J. Arlos

et al.

Published: Jan. 1, 2023

To evaluate effects of tertiary treated wastewater treatment plant effluent (MWWE) on transcriptomic responses in longnose dace (Rhinichthys cataractae; LND) we conducted a semi-controlled study experimental raceways (Advancing Canadian Water Assets facility) imbedded the Pine Creek (Calgary, AB). LND collected from reference site Bow River (REF) were caged containing either 5% (PC) or water (BR; control) over 28 d. Liver transcriptomes analyzed males and females sampled days 7, 14 BR PC, compared to REF fish day 0. Concurrent with caging, selected environmental substances concern analysed PC. Significantly different unigenes (SDUs) (vs males) within both PC increased time fish. Moreover, SDUs same (i.e., BR, PC) showed temporal increase as well Time was dominant factor affecting SDUs, whereas sex had less an impact transcriptome profiling. Gene Set Enrichment Analysis vs revealed genes involved growth, metabolism carbohydrates lipids, immune system 7; however, by 28, 80-100% transcripts localized enriched biomarkers associated tissue sexes. Exposure significant female liver somatic index but no observed other phenotypic health indices sex. used source water, analyses trace amounts ESOCs. Analyses did not point towards definitive response patterns that could be field-based ecotoxicogenomic studies impacts well-treated MWWE suggested compromised adaptive responses.

Language: Английский

Impacts of municipal wastewater treatment plant discharge on microbial community structure and function of the receiving river in Northwest Tibetan Plateau DOI
Jiawen Wang, Ying Chen,

Pinggui Cai

et al.

Journal of Hazardous Materials, Journal Year: 2021, Volume and Issue: 423, P. 127170 - 127170

Published: Sept. 12, 2021

Language: Английский

Citations

60

Impact of industrial effluents on the environment and human health and their remediation using MOFs-based hybrid membrane filtration techniques DOI
Kandasamy Saravanakumar, Shanali De Silva,

Sugavaneswaran Siva Santosh

et al.

Chemosphere, Journal Year: 2022, Volume and Issue: 307, P. 135593 - 135593

Published: July 6, 2022

Language: Английский

Citations

58

Environmental parasitology: stressor effects on aquatic parasites DOI Open Access
Bernd Sures, Milen Nachev, Jessica Schwelm

et al.

Trends in Parasitology, Journal Year: 2023, Volume and Issue: 39(6), P. 461 - 474

Published: April 14, 2023

Language: Английский

Citations

31

Applying genetic technologies to combat infectious diseases in aquaculture DOI Creative Commons
Nicholas A. Robinson, Diego Robledo, Lene Sveen

et al.

Reviews in Aquaculture, Journal Year: 2022, Volume and Issue: 15(2), P. 491 - 535

Published: Sept. 5, 2022

Disease and parasitism cause major welfare, environmental economic concerns for global aquaculture. In this review, we examine the status potential of technologies that exploit genetic variation in host resistance to tackle problem. We argue there is an urgent need improve understanding mechanisms involved, leading development tools can be applied boost reduce disease burden. draw on two pressing problems as case studies-sea lice infestations salmonids white spot syndrome shrimp. review how latest capitalised upon determine underlying inter- intra-species pathogen/parasite resistance, derived knowledge could using selective breeding, gene editing and/or with targeted feed treatments vaccines. Gene brings novel opportunities, but also implementation dissemination challenges, necessitates new protocols integrate technology into aquaculture breeding programmes. There ongoing minimise risks agents evolving overcome improvements insights from epidemiological evolutionary models pathogen infestation wild cultured populations are explored. Ethical issues around different approaches achieving discussed. Application has fundamental affecting provide effective pathways lead more resistant stocks, transforming

Language: Английский

Citations

36

Seasonal variation in structural and functional distribution of periphyton in a macrolide antibiotics-contaminated river DOI

Baihuan Zhang,

Wenqian Yu, Jiayi Liang

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 345, P. 123495 - 123495

Published: Feb. 9, 2024

Language: Английский

Citations

6

Spatial and temporal distribution of the microbial community structure in the receiving rivers of the middle and lower reaches of the Yangtze River under the influence of different wastewater types DOI

Rui Bian,

Shier Huang,

Xiaofeng Cao

et al.

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 462, P. 132835 - 132835

Published: Oct. 21, 2023

Language: Английский

Citations

11

Intensified anthropogenic disturbances impair planktonic algae in an urban river DOI
Jiawen Wang,

Shanqing Yang,

Yucheng Tian

et al.

Journal of Cleaner Production, Journal Year: 2024, Volume and Issue: 468, P. 143091 - 143091

Published: July 6, 2024

Language: Английский

Citations

4

Perfluorobutane Sulfonate (PFOS) Accumulation in Tissues of Cherax quadricarinatus and Its Toxicity Mechanism DOI Creative Commons

Shuang Hong,

Tian Zhu, Chengbin Liu

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(4), P. 269 - 269

Published: April 1, 2025

Perfluoroctane sulfonate (PFOS) is an emerging pollutant widely existing in aquatic environments that has attracted many scholars’ attention. Cherax quadricarinatus (C. quadricarinatus) are crustaceans live freshwater environments. This study aimed to investigate the long-term toxic exposure effect of PFOS on C. quadricarinatus. Three environment concentrations (1 ng/L, 100 and 10 μg/L) were set for 28 days The results indicated was detected serum, muscle, hepatopancreas quadricarinatus, order accumulation levels as follows: > serum muscle. Furthermore, transcriptomics showed function differentially expressed genes (DEGs) groups related biological processes, metabolism, organic system, immune response. Kyoto Encyclopedia Genes Genomes enrichment analysis DEGs significantly enriched lysosome signaling pathway, retinol binding, fructose mannose glutathione etc., pathway most significant, which key effects

Language: Английский

Citations

0

Integrated analysis highlights multiple long non‑coding RNAs and their potential roles in the progression of human esophageal squamous cell carcinoma DOI Creative Commons
Chengyun Li, Wenwen Zhang,

Jilian Xiang

et al.

Oncology Reports, Journal Year: 2019, Volume and Issue: unknown

Published: Oct. 17, 2019

Esophageal squamous cell carcinoma (ESCC) is a prevalent aggressive malignant tumor with poor prognosis. Investigations into the molecular changes that occur as result of disease, well identification novel biomarkers for its diagnosis and prognosis, are urgently required. Long non‑coding RNAs (lncRNAs) have been reported to play critical role in progression. The present study performed data mining analyses ESCC via an integrated accumulated datasets differentially expressed lncRNAs from Gene Expression Omnibus (GEO) Cancer Genome Atlas (TCGA) databases. identified intersection genes (lncRNAs, miRNAs mRNAs) tissues between GEO TCGA was investigated. Based on these intersected lncRNAs, constructed competitive endogenous RNA (ceRNA) network ESCC. A total 81 were identified; 67 included ceRNA network. Functional revealed key primarily dominated cellular biological processes. then analyzed associations expression levels clinicopathological characteristics patients, their survival time using TCGA. results 31 associated grade, tumor‑node‑metastasis (TNM) stage lymphatic metastasis status (P<0.05). In addition, 15 demonstrated be Finally, 5 selected validation 30 patients newly diagnosed reverse transcription‑quantitative PCR (RT‑qPCR). suggested fold trends up‑ downregulation GEO, RT‑qPCR consistent. it also select few significantly TNM lymph node clinically relevant analysis aforementioned bioinformatics similar, hence proving used credible. Overall, may provide further insight functional through integrative datasets, reveal potential diagnostic prognostic

Language: Английский

Citations

28

Applications of Next-Generation Sequencing Technologies and Computational Tools in Molecular Evolution and Aquatic Animals Conservation Studies: A Short Review DOI Creative Commons
Min Pau Tan, Li Lian Wong, Siti Aisyah Razali

et al.

Evolutionary Bioinformatics, Journal Year: 2019, Volume and Issue: 15, P. 117693431989228 - 117693431989228

Published: Jan. 1, 2019

Aquatic ecosystems that form major biodiversity hotspots are critically threatened due to environmental and anthropogenic stressors. We believe that, in this genomic era, computational methods can be applied promote aquatic conservation by addressing questions related the evolutionary history of organisms at molecular level. However, huge amounts genomics data generated only discerned through use bioinformatics. Here, we examine applications next-generation sequencing technologies bioinformatics tools study evolution animals discuss current challenges future perspectives using toward animal efforts.

Language: Английский

Citations

24