Frontiers in quantifying wildlife behavioural responses to chemical pollution

Biological reviews/Biological reviews of the Cambridge Philosophical Society, Journal Year: 2022, Volume and Issue: 97(4), P. 1346 - 1364

Published: March 1, 2022

Animal behaviour is remarkably sensitive to disruption by chemical pollution, with widespread implications for ecological and evolutionary processes in contaminated wildlife populations. However, conventional approaches applied study the impacts of pollutants on seldom address complexity natural environments which contamination occurs. The aim this review guide rapidly developing field behavioural ecotoxicology towards increased environmental realism, complexity, mechanistic understanding. We identify research areas ecology that date have been largely overlooked within but promise yield valuable insights, including within- among-individual variation, social networks collective behaviour, multi-stressor interactions. Further, we feature methodological technological innovations enable collection data pollutant-induced changes at an unprecedented resolution scale laboratory field. In era rapid change, there urgent need advance our understanding real-world pollution behaviour. This therefore provides a roadmap major outstanding questions highlights cross-talk other disciplines order find answers.

Language: Английский

---

Combined methods elucidate the multi-organ toxicity of cylindrospermopsin (CYN) on Daphnia magna

Environmental Pollution, Journal Year: 2023, Volume and Issue: 324, P. 121250 - 121250

Published: Feb. 20, 2023

Language: Английский

---

Zebrafish Larvae Rapidly Recover from Locomotor Effects and Neuromuscular Alterations Induced by Cholinergic Insecticides

Environmental Science & Technology, Journal Year: 2022, Volume and Issue: 56(12), P. 8449 - 8462

Published: May 16, 2022

Owing to the importance of acetylcholine as a neurotransmitter, many insecticides target cholinergic system. Across phyla, signaling is essential for neuro-developmental processes including axonal pathfinding and synaptogenesis. Consequently, early-life exposure such can disturb these processes, resulting in an impaired nervous One test frequently used assess developmental neurotoxicity zebrafish light–dark transition test, which measures larval locomotion response light changes. However, it only poorly understood structural alterations cause insecticide-induced defects how persistent are. Therefore, this study aimed link with effects on neuromuscular structures, motorneurons, synapses, muscles, investigate longevity effects. The diazinon dimethoate (organophosphates), methomyl pirimicarb (carbamates), imidacloprid thiacloprid (neonicotinoids) were induce hypoactivity. Our analyses revealed that some did not alter any structures assessed, while others affected axon branching (methomyl, imidacloprid) or muscle integrity thiacloprid). majority effects, even structural, reversible within 24 72 h. Overall, we find both neurodevelopmental non-neurodevelopmental different account reduced locomotion. These findings provide unprecedented insights into underpinnings

Language: Английский

---

Screening and risk assessment of priority organic micropollutants for control in reclaimed water in China

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 491, P. 137883 - 137883

Published: March 10, 2025

Language: Английский

---

Generalized additive modeling as a tool for the analysis of the time course of tail coiling behavior in zebrafish (Danio rerio) embryos – a proof-of-concept study with nicotine, a known developmental neurotoxicant

Aquatic Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 107373 - 107373

Published: April 1, 2025

Language: Английский

---

EthoCRED: a framework to guide reporting and evaluation of the relevance and reliability of behavioural ecotoxicity studies

Biological reviews/Biological reviews of the Cambridge Philosophical Society, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 12, 2024

ABSTRACT Behavioural analysis has been attracting significant attention as a broad indicator of sub‐lethal toxicity and secured place an important subdiscipline in ecotoxicology. Among the most notable characteristics behavioural research, compared to other established approaches ecotoxicology (e.g. reproductive developmental bioassays), are wide range study designs being used diversity endpoints considered. At same time, environmental hazard risk assessment, which underpins regulatory decisions protect environment from potentially harmful chemicals, often recommends that ecotoxicological data be produced following accepted validated test guidelines. These guidelines typically do not address changes, meaning these, sensitive, effects represented assessments. Here, we propose new tool, EthoCRED evaluation method, for assessing relevance reliability ecotoxicity data, considers unique requirements challenges encountered this field. This method accompanying reporting recommendations designed serve extension “Criteria Reporting Evaluating Ecotoxicity Data (CRED)” project. As such, can both accommodate array experimental design seen ecotoxicology, could readily implemented into frameworks deemed appropriate by policy makers different jurisdictions allow better integration knowledge gained testing protection. Furthermore, through our recommendations, aim improve studies peer‐reviewed literature, thereby increase their usefulness inform chemical regulation.

Language: Английский

---

Beyond the behavioural phenotype: Uncovering mechanistic foundations in aquatic eco-neurotoxicology

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 829, P. 154584 - 154584

Published: March 16, 2022

Language: Английский

---

Developmental Neurotoxicity and Behavioral Screening in Larval Zebrafish with a Comparison to Other Published Results

Toxics, Journal Year: 2022, Volume and Issue: 10(5), P. 256 - 256

Published: May 17, 2022

With the abundance of chemicals in environment that could potentially cause neurodevelopmental deficits, there is a need for rapid testing and chemical screening assays. This study evaluated developmental toxicity behavioral effects 61 zebrafish (Danio rerio) larvae using Light/Dark assay. Larvae (n = 16–24 per concentration) were exposed to each (0.0001–120 μM) during development locomotor activity was assessed. Approximately half 30) did not show any gross (i.e., mortality, dysmorphology or non-hatching) at highest concentration tested. Twelve 31 elicit toxic only, thirteen developmentally concentrations 10 µM lower. Eleven caused effects; four (6-aminonicotinamide, cyclophosphamide, paraquat, phenobarbital) altered behavior absence toxicity. In addition library neurotoxicity, we also compared our findings with previously published results those chemicals. Our comparison revealed general lack standardized reporting experimental details, it helped identify some appear be consistent positives negatives across multiple laboratories.

Language: Английский

---

High-throughput screening paradigms in ecotoxicity testing: Emerging prospects and ongoing challenges

Chemosphere, Journal Year: 2022, Volume and Issue: 307, P. 135929 - 135929

Published: Aug. 6, 2022

Language: Английский

---

Comparative behavioral ecotoxicology of Inland Silverside larvae exposed to pyrethroids across a salinity gradient

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 857, P. 159398 - 159398

Published: Oct. 17, 2022

Language: Английский

---