Contacts with environmental biodiversity affect human health: links to allergies, physical and mental health revealed during the initial waves of the COVID-19 pandemic DOI Creative Commons
Daniel Divín, Ján Toman, Jaroslav Flegr

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: March 27, 2024

Abstract The gradual decrease in the prevalence of serious infectious diseases over last century has been followed by increase so called “modern” diseases, including allergies, chronic inflammatory conditions, psychiatric, and metabolic disorders. Between 2019 2022, public awareness threat humans was renewed global pandemic a new type coronavirus, SARS-COV-2. This interest opened improved possibilities to test hypotheses on factors associated with inter-individual variation susceptibility diseases. Based Hygiene hypothesis Biodiversity hypothesis, we predicted that contacts natural environment wildlife childhood and/or adulthood can improve general health risks severe COVID-19 progression or namely allergies. Here report results an online, self-evaluating questionnaire survey conducted Czech Republic, where contrasted selected issues, linked them living environment, level biodiversity. In sample 1188 respondents, revealed significant effect time spent nature biodiversity physical mental health, incidence is unlike progression, which related age, smoking, interaction age but not environmental diversity. Our findings are agreement allergy and, linking human they urge for One Health approach application.

Language: Английский

Institutionalising Multispecies Justice DOI Creative Commons
Danielle Celermajer, Anthony Burke, Stefanie Fishel

et al.

Published: Jan. 29, 2025

Multispecies Justice (MSJ) is a theory and practice seeking to correct the defects making dominant theories of justice incapable responding current emerging planetary disruptions extinctions. starts with assumption that not limited humans but includes all Earth others, relationships enable their functioning flourishing. This Element describes imagines set institutions, across scales in different spheres, respect, revere, care for make life on possible allow natural entities, included, flourish. It draws attention prefigurative work happening within societies otherwise dominated by institutions characterised Injustice, demonstrating historical ongoing practices MSJ contexts. then sketches speculative possibilities expand existing institutional reforms are more fundamentally transformational. title also available as Open Access Cambridge Core.

Language: Английский

Citations

3
Recent progress of microneedles in transdermal immunotherapy: A review DOI
Xinyi Ai,

Jiayi Yang,

Zhenda Liu

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 662, P. 124481 - 124481

Published: July 23, 2024

Language: Английский

Citations

10
Greenspace and human microbiota: A systematic review DOI Creative Commons
Yidan Zhang,

Gang-Long Zhou,

Lu Wang

et al.

Environment International, Journal Year: 2024, Volume and Issue: 187, P. 108662 - 108662

Published: April 16, 2024

Potential effect of greenspace exposure on human microbiota have been explored by a number observational and interventional studies, but the results remained mixed. We comprehensively synthesized these studies performing systematic review following PRISMA guidelines. Comprehensive literature searches in three international databases (PubMed, Embase, Web Science) Chinese (China National Knowledge Infrastructure, Wanfang, China Biology Medicine disc) were conducted from inception to November 1, 2023. Observational that evaluated associations between at different anatomical sites included. Studies assessed using Toxicology Program's office Health Assessment Translation (OHAT) risk bias tool certainty evidence was Grading Recommendations, Assessment, Development Evaluation (GRADE) framework. Two authors independently performed study selection, data extraction, assessment, grading. Study descriptively. Twenty including 11 9 finally included into review. The gut (n = 13), skin 10), oral cavity 5), nasal 5) eyes 1). majority reported with increased diversity (e.g., richness Shannon index) and/or altered overall composition 12) 8), increases relative abundance probiotics Ruminococcaceae) decreases pathogens Streptococcus Escherichia/Shigella). Due limited concerning oral, nasal, ocular still inconclusive. current suggests may diversify alter their healthier profiles. These findings would be helpful uncovering potential mechanisms underlying health promoting profile microbiota.

Language: Английский

Citations

8
Fermented natural product targeting gut microbiota regulate immunity and anti-inflammatory activity: A possible way to prevent COVID-19 in daily diet DOI Creative Commons

Quancen Li,

Na Li,

Wenwen Cai

et al.

Journal of Functional Foods, Journal Year: 2022, Volume and Issue: 97, P. 105229 - 105229

Published: Aug. 22, 2022

Low immune function makes the body vulnerable to being invaded by external bacteria or viruses, causing influenza and inflammation of various organs, this trend is shifting young middle-aged group. It has been pointed out that natural products fermented probiotic have benign changes about their active ingredients in some studies, it shown strong nutritional value anti-oxidation, anti-aging, regulating lipid metabolism, anti-inflammatory improving immunity. In recent years, gut microbiota plays a key role extensively studied immunity anti-inflammation activity. By linking relationship between probiotic, microbiota, immunity, inflammation, review presents modulating effects probiotics on body, including immunity-enhancing activities discussed current understanding its molecular mechanisms. may become possible way prevent COVID-19 through consuming our daily diet.

Language: Английский

Citations

23
The Role of Biodiversity in the Development of Asthma and Allergic Sensitization: A State-of-the-Science Review DOI Creative Commons
Inês Paciência,

Needhi Sharma,

Timo T. Hugg

et al.

Environmental Health Perspectives, Journal Year: 2024, Volume and Issue: 132(6)

Published: June 1, 2024

Changes in land use and climate change have been reported to reduce biodiversity of both the environment human microbiota. These reductions may lead inadequate unbalanced stimulation immunoregulatory circuits and, ultimately, clinical diseases, such as asthma allergies.

Language: Английский

Citations

6
Gut microbiota and immunity in health and diseases: a review DOI

Michael Chukwuma Okolie,

Great Iruoghene Edo,

Irene Ebosereme Ainyanbhor

et al.

DELETED, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

Language: Английский

Citations

5
Urban indoor gardening enhances immune regulation and diversifies skin microbiota — A placebo-controlled double-blinded intervention study DOI Creative Commons
Mika Saarenpää, Marja I. Roslund, Noora Nurminen

et al.

Environment International, Journal Year: 2024, Volume and Issue: 187, P. 108705 - 108705

Published: April 26, 2024

According to the hygiene and biodiversity hypotheses, frequent exposure environmental microbiota, especially through soil contact, diversifies commensal enhances immune modulation, ultimately lowers risk of immune-mediated diseases. Here we test underlying assumption hypotheses by instructing volunteers grow edible plants indoors during winter season when natural microbiota is low. The one-month randomized, placebo-controlled double-blind trial consisted two treatments: participants received either microbially diverse growing medium or visually similar but poor medium. Skin a panel seven markers were analyzed in beginning after one month. diversity five bacterial phyla (Bacteroidetes, Planctomycetes, Proteobacteria, Cyanobacteria, Verrucomicrobia) class (Bacteroidia) increased on skin intervention group while no changes observed placebo group. number nodes edges co-occurrence networks bacteria average three times more than plasma levels immunomodulatory cytokine interleukin 10 (IL-10) compared with A trend was 17A (IL-17A) IL-10:IL-17A ratios. Participants both groups reported high satisfaction adherence trial. current study provides evidence support core Indoor urban gardening offers meaningful convenient approach for increasing year-round paving way other prophylactic practices that might help prevent

Language: Английский

Citations

4
Pathways Through Which Green Exposure Type Influences Cardiovascular Diseases Mortality in Shanghai, China DOI Creative Commons
Jianzhong Huang, Yang Xu, Lan Wang

et al.

Landscape Architecture, Journal Year: 2025, Volume and Issue: 32(2), P. 72 - 78

Published: Feb. 1, 2025

Language: Английский

Citations

0
A short history from Karelia study to biodiversity and public health interventions DOI Creative Commons
Tari Haahtela, Harri Alenius, Petri Auvinen

et al.

Frontiers in Allergy, Journal Year: 2023, Volume and Issue: 4

Published: March 14, 2023

Contact with natural environments enriches the human microbiome, promotes immune balance and protects against allergies inflammatory disorders. In Finland, allergy & asthma epidemic became slowly visible in mid 1960s. After World War II, Karelia was split into Finnish Soviet Union (now Russia) territories. This led to more marked environmental lifestyle changes compared Russian Karelia. The Allergy Study 2002–2022 showed that allergic conditions were much common on side. Russians had richer gene-microbe network interaction than Finns, which associated better balanced regulatory circuits lower prevalence. adolescents, a biodiverse environment around homes occurrence of allergies. Overall, plausible explanation disparity prominent change from 1940s 1980s. nationwide Programme 2008–2018 implemented biodiversity hypothesis practice by endorsing tolerance, nature contacts, health favorable results. A regional programme, Nature Step Health 2022–2032 , has been initiated City Lahti, EU Green Capital 2021. programme integrates prevention chronic diseases (asthma, diabetes, obesity, depression), loss, climate crisis spirit Planetary . Allergic exemplify inappropriate immunological responses environment. Successful management epidemics other non-communicable may pave way improve health.

Language: Английский

Citations

8
Suitability changes of Citrus medica L. var. sarcodactylis Swingle, a medicine-food plants affected by climate warming using the optimized MaxEnt model DOI Creative Commons
Yanli Xia, Muhammad Kazim,

Muhammad Nabeel Nasir

et al.

PLoS ONE, Journal Year: 2023, Volume and Issue: 18(3), P. e0282659 - e0282659

Published: March 31, 2023

Climatic variables are important conditions for plant growth, development and reproduction. Citrus medica L. var. sarcodactylis Swingle (Rutaceae: ) is one of the traditional bulk Chinese medicinal materials in China with effects bacteriostasis, anti-inflammatory, anti-oxidation, anti-cancer cells, regulating immun. Analyzing impact climate change on geographical distribution C . can provide strong support its production layout agricultural zoning. In our paper, MaxEnt ArcGIS were applied to simulate suitable areas from perspectives bioclimate, soil, topographic factors human activities, future scenarios generated by global models (GCMs) selected predict 2050s 2090s. Results showed that, 1) Under current condition, total, most, moderately poorly habitats 177.36×10 4 km 2 , 22.27×10 51.96×10 103.13×10 respectively. The range most habitat was narrowest, which located middle east Sichuan, western Chongqing upstream Yangtze River Basin, southern Guizhou Guangxi Pearl central Yunnan Southeast Tibet Middle-Lower reaches Southwest Basin Taiwan. 2) scenarios, total area a significant increase trend 2090s, no obvious law. 3) SSP1-2.6, SSP2-4.5 SSP5-8.5 centroid would move northwest, southeast southwest

Language: Английский

Citations

8