The honeybee microbiota and its impact on health and disease

Nature Reviews Microbiology, Journal Year: 2023, Volume and Issue: 22(3), P. 122 - 137

Published: Dec. 4, 2023

Language: Английский

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Pesticide exposure and the microbiota-gut-brain axis

The ISME Journal, Journal Year: 2023, Volume and Issue: 17(8), P. 1153 - 1166

Published: June 16, 2023

Abstract The gut microbiota exist within a dynamic ecosystem shaped by various factors that includes exposure to xenobiotics such as pesticides. It is widely regarded the plays an essential role in maintaining host health, including major influence on brain and behaviour. Given widespread use of pesticides modern agriculture practices, it important assess long-term collateral effects these xenobiotic exposures have composition function. Indeed, studies using animal models shown can induce negative impacts microbiota, physiology health. In tandem, there growing body literature showing pesticide be extended manifestation behavioural impairments host. With increasing appreciation microbiota-gut-brain axis, this review we whether pesticide-induced changes profiles functions could driving alterations. Currently, diversity type, dose variation experimental designs hinders direct comparisons presented. Although many insights presented, mechanistic connection between remains insufficiently explored. Future experiments should therefore focus causal mechanisms examine mediator observed following exposure.

Language: Английский

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Chronic Exposure to Polystyrene Microplastic Fragments Has No Effect on Honey Bee Survival, but Reduces Feeding Rate and Body Weight

Toxics, Journal Year: 2023, Volume and Issue: 11(2), P. 100 - 100

Published: Jan. 21, 2023

Microplastics (MPs), in the form of fragments and fibers, were recently found honey samples collected Ecuador as well bees from Denmark China. However, little is known about how MPs impact bee health. To fill this knowledge gap, we investigated potential toxicity irregularly shaped polystyrene (PS)-MP on In first experiment its kind with bees, chronically exposed a well-established gut microbiome to small (27 ± 17 µm) or large (93 25 PS-MP at varying concentrations (1, 10, 100 µg mL−1) for 14 days. Bee mortality, food consumption, body weight all studied. We that chronic exposure has no effect survival, but reduced feeding rate weight, particularly 10 per mL, which may have long-term consequences The findings study could assist risk assessment pollinator

Language: Английский

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The effects of glyphosate, pure or in herbicide formulation, on bumble bees and their gut microbial communities

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 872, P. 162102 - 162102

Published: Feb. 9, 2023

Language: Английский

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Bees just wanna have fungi: a review of bee associations with nonpathogenic fungi

FEMS Microbiology Ecology, Journal Year: 2023, Volume and Issue: 99(8)

Published: July 7, 2023

Abstract Bee–fungus associations are common, and while most studies focus on entomopathogens, emerging evidence suggests that bees associate with a variety of symbiotic fungi can influence bee behavior health. Here, we review nonpathogenic fungal taxa associated different species bee-related habitats. We synthesize results examining effects behavior, development, survival, fitness. find communities differ across habitats, some groups restricted mostly to flowers (Metschnikowia), others present almost exclusively in stored provisions (Zygosaccharomyces). Starmerella yeasts found multiple habitats association many species. Bee widely the abundance identity hosted. Functional suggest affect foraging, pathogen interactions, though few have been examined this context. Rarely, obligately beneficial symbionts bees, whereas facultative associates unknown or ecologically contextual effects. Fungicides reduce alter potentially disrupting bee–fungi associations. recommend future study non-honeybee examine life stages document composition, abundance, mechanistic bees.

Language: Английский

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Unravelling the microplastic menace: Different polymers additively increase bee vulnerability

Environmental Pollution, Journal Year: 2024, Volume and Issue: 352, P. 124087 - 124087

Published: May 2, 2024

Microplastics (MPs) are growing and ubiquitous environmental pollutants represent one of the greatest contemporary challenges caused by human activities. Current research has predominantly examined singular toxicological effects individual polymers, neglecting prevailing reality organisms confronted with complex contaminant mixtures potential synergistic effects. To fill this gap, we investigated lethal sublethal two common MPs, polystyrene (PS - 4.8-5.8 μm) poly(methyl methacrylate) (PMMA 1-40 μm), their combination (MIX), on pollinating insect Apis mellifera. For each treatment, evaluated oral toxicity ecologically relevant higher concentration (0.5, 5 50 mg/L) analysed immune system worker survival. As activation can alter cuticular hydrocarbon profile honey bees, used gas chromatography-mass spectrometry (GC-MS) to investigate whether MPs lead changes in chemical foragers behavioural assay test such affect patterns social recognition, undermining overall colony integrity. The results indicate an additive negative effect PS PMMA bee survival response, even at concentrations. Furthermore, alterations cuticle profiles were observed both highest intermediate concentrations, being mainly responsible. Both exposure resulted a reduction abundance several compounds. Hive entry guards did not show increased inspection or aggressive behaviour towards exposed foragers, allowing them enter without treated differently from uncontaminated foragers. These findings raise concerns only for health but also entire colony, which could be risk if contaminated nestmates undetected, spread throughout hive.

Language: Английский

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Vairimorpha (Nosema) ceranae can promote Serratia development in honeybee gut: an underrated threat for bees?

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: May 13, 2024

The genus Serratia harbors opportunistic pathogenic species, among which marcescens is for honeybees although little studied. Recently, virulent strains of S. colonizing the Varroa destructor mite’s mouth were found vectored into honeybee body, leading to septicemia and death. also occurs as an pathogen in honeybee’s gut with a low absolute abundance. population seems controlled by host immune system, but its presence may represent hidden threat, ready arise when are weakened biotic abiotic stressors. To shed light on pathogen, this research aims at studying ’s development dynamics body interactions co-occurring fungal Vairimorpha ceranae . Firstly, degree pathogenicity ability permeate epithelial barrier three strains, isolated from belonging different species ( , liquefaciens nematodiphila ), assessed artificial inoculation newborn doses (10 4 10 6 8 cells/mL). abundance hemocoel was qPCR primers targeting luxS gene. Moreover, infected V. stages supplied beneficial microorganisms fumagillin. Our results showed that all tested could pass through proliferate hemocoel, being most pathogenic. under cage conditions, better proliferates infection co-occurring, positive significant correlation. Finally, fumagillin some control both development. findings suggest correlation between two pathogens laboratory should be taken consideration researches testing antimicrobial compounds active against related survival rate. our environmental microorganism Apilactobacillus kunkeei vivo model, confirming potential specie bacteria honeybees.

Language: Английский

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Systemic pesticides in a solitary bee pollen food store affect larval development and increase pupal mortality

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 915, P. 170048 - 170048

Published: Jan. 12, 2024

Language: Английский

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Agrochemical pollution: a serious threat to environmental health

Current Opinion in Environmental Science & Health, Journal Year: 2025, Volume and Issue: unknown, P. 100597 - 100597

Published: Jan. 1, 2025

Language: Английский

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Co-exposure to a honeybee pathogen and an insecticide: synergistic effects in a new solitary bee host but not in Apis mellifera

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2025, Volume and Issue: 292(2042)

Published: March 1, 2025

Pesticides and pathogens are major drivers of bee declines. However, their potential interactions poorly understood, especially for non-Apis bees. This study assessed the combined effects infestation by honeybee pathogen Vairimorpha ceranae chronic exposure to insecticide flupyradifurone on Osmia bicornis Apis mellifera. We investigated whether V. could reproduce in a new solitary host (O. bicornis) sublethal lethal pesticide, alone combination. also analysed interactive proliferation survival two species. Newly emerged bees were orally infected with 100 000 spores then exposed ad libitum at field-realistic concentrations. showed, first time our knowledge, that can replicate midgut O. bicornis, causing histological damage, impaired phototactic response, reduced food consumption decreased longevity. The pathogen-pesticide combination caused synergistic effect leading an abrupt decline. In A. mellifera, showed antagonistic effects, but pesticide promoted proliferation. Our results warn against spillover multiple stressor

Language: Английский

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