Microplastics exposure: implications for human fertility, pregnancy and child health

Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 14

Published: Jan. 4, 2024

Plastics found in our everyday environment are becoming an increasing concern for individual and population-level health, the extent of exposure potential toxic effects these contaminants on numerous human organ systems clear. Microplastics (MPs), tiny plastic particles, appear to have many same biological as their precursors compounded effect accumulation different organs. Recently, microplastic was observed placenta, raising important questions related health pregnancies offspring. These concerns particularly heightened considering developmental origins disease (DOHaD) framework, which postulates that utero can programme lifelong The current review examines state knowledge this topic highlights avenues future investigation.

Language: Английский

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Beyond the cradle – Amidst microplastics and the ongoing peril during pregnancy and neonatal stages: A holistic review

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 469, P. 133963 - 133963

Published: March 6, 2024

Language: Английский

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Hemolytic Activity of Nanoparticles as a Marker of Their Hemocompatibility

Micromachines, Journal Year: 2022, Volume and Issue: 13(12), P. 2091 - 2091

Published: Nov. 27, 2022

The potential use of nanomaterials in medicine offers opportunities for novel therapeutic approaches to treating complex disorders. For that reason, a new branch science, named nanotoxicology, which aims study the dangerous effects on human health and environment, has recently emerged. However, toxicity risk associated with are unclear or not completely understood. development an adequate experimental strategy assessing may include rapid/express method will reliably, quickly, cheaply make initial assessment. One possibility is characterization hemocompatibility nanomaterials, includes their hemolytic activity as marker. In this review, we consider various factors affecting draw reader’s attention fact formation protein corona around nanoparticle can significantly change its interaction red cell. This leads us suggest nanomaterial buffer does reflect situation blood plasma. As recommendation, propose studying under more physiologically relevant conditions, presence plasma proteins medium mechanical stress.

Language: Английский

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Microplastic exposure induces muscle growth but reduces meat quality and muscle physiological function in chickens

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 882, P. 163305 - 163305

Published: April 11, 2023

Language: Английский

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Fate and environmental behaviors of microplastics through the lens of free radical

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 453, P. 131401 - 131401

Published: April 13, 2023

Language: Английский

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Polystyrene nanoparticle exposure accelerates ovarian cancer development in mice by altering the tumor microenvironment

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 906, P. 167592 - 167592

Published: Oct. 5, 2023

Language: Английский

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Nano- and Microplastics Migration from Plastic Food Packaging into Dairy Products: Impact on Nutrient Digestion, Absorption, and Metabolism

Foods, Journal Year: 2023, Volume and Issue: 12(16), P. 3043 - 3043

Published: Aug. 14, 2023

The ongoing use of plastic polymers to manufacture food packaging has raised concerns about the presence nano- and microplastics (NMPs) in a variety foods. This review provides most recent data on NMPs' migration from into dairy products. Also discussed are possible effects NMPs nutrient digestion, absorption, metabolism. Different kinds products, including skimmed milk, whole liquid powder infant formula have been found contain various sizes, shapes, concentrations. may interact with proteins, carbohydrates, fats detrimental impact how well these nutrients digested absorbed by body. gastrointestinal tract lipids, glucose, iron, energy metabolized, increasing risk developing health conditions. In addition NMPs, oligomers released material migrate foods simulants, though information regarding their effect human is limited. Viewpoints potential directions for future studies also presented this review.

Language: Английский

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Maternal exposure to polyethylene micro- and nanoplastics impairs umbilical blood flow but not fetal growth in pregnant mice

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Jan. 3, 2024

Abstract While microplastics have been recently detected in human blood and the placenta, their impact on health is not well understood. Using a mouse model of environmental exposure during pregnancy, our group has previously reported that to polystyrene micro- nanoplastics throughout gestation results fetal growth restriction. environmentally relevant, polyethylene most widely produced plastic amongst commonly microplastic drinking water blood. In this study, we investigated effect maternal placental function. Healthy, pregnant CD-1 dams were divided into three groups: 10 6 ng/L 740–4990 nm with surfactant ( n = 12), alone 12) or regular filtered 11). At embryonic day 17.5, high-frequency ultrasound was used investigate hemodynamic responses following exposure. did growth, there significant function 43% increase umbilical artery flow compared controls (p < 0.01). These suggest potential cause adverse pregnancy outcomes through abnormal

Language: Английский

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Maternal exposure to polystyrene nanoplastics causes defective retinal development and function in progeny mice by disturbing metabolic profiles

Chemosphere, Journal Year: 2024, Volume and Issue: 352, P. 141513 - 141513

Published: Feb. 20, 2024

Language: Английский

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Degradation of Polymer Materials in the Environment and Its Impact on the Health of Experimental Animals: A Review

Polymers, Journal Year: 2024, Volume and Issue: 16(19), P. 2807 - 2807

Published: Oct. 3, 2024

The extensive use of polymeric materials has resulted in significant environmental pollution, prompting the need for a deeper understanding their degradation processes and impacts. This review provides comprehensive analysis environment impact on health experimental animals. It identifies common polymers, delineates pathways, describes resulting products under different conditions. covers physical, chemical, biological mechanisms, highlighting complex interplay factors influencing these processes. Furthermore, it examines implications products, using animals as proxies assessing potential risks to human health. By synthesizing current research, focuses studies related small organisms (primarily rodents invertebrates, supplemented by fish mollusks) explore effects polymer living underscores urgency developing implementing effective waste management strategies. These strategies are crucial mitigating adverse impacts degradation, thus promoting more sustainable interaction between activities natural environment.

Language: Английский

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