Assessment of selected pharmaceuticals in Riyadh wastewater treatment plants, Saudi Arabia: Mass loadings, seasonal variations, removal efficiency and environmental risk

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 882, P. 163284 - 163284

Published: April 7, 2023

Language: Английский

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Wastewater-based epidemiology to monitor 68 NPS/conventional drug use in Taipei metropolitan area in Taiwan during and after COVID-19 pandemic

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 476, P. 135020 - 135020

Published: June 29, 2024

Language: Английский

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Consumption of illicit drugs and benzodiazepines in six Spanish cities during different periods of the COVID-19 pandemic

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 935, P. 173356 - 173356

Published: May 19, 2024

Wastewater-based epidemiology (WBE) can provide objective and real time information about the use of addictive substances. A national study was conducted by measuring most consumed illicit drugs, other drugs whose consumption is not so widespread but has increased significantly in recent years, benzodiazepines untreated wastewater from seven treatment plants (WWTPs) six Spanish cities. Raw composite samples were collected December 2020 to 2021, a period which regional governments adopted different restriction measures contain spread COVID-19 pandemic. Samples analyzed using validated analytical methodology for simultaneous determination 18 substances, based on solid-phase extraction liquid-chromatography tandem mass spectrometry. Except heroin, fentanyl, 6-acetylmorphine alprazolam, all compounds found at least one city 9 out samples. In general, particularly high cities monitored 2020, when restrictions more severe, especially cannabis cocaine with values up 46 6.9 g/day/1000 inhabitants (g/day/1000 inh), respectively. The MDMA, methamphetamine mephedrone notably higher June after end state alarm, biggest population investigated this study. Regarding benzodiazepines, highest loads corresponded lorazepam. This demonstrates that WBE suitable complementing epidemiological studies prevalence during pandemic restrictions.

Language: Английский

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Tracking methamphetamine and amphetamine consumption patterns in South Korea via enantiomeric analysis of wastewater

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 905, P. 166910 - 166910

Published: Sept. 7, 2023

Language: Английский

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Do the lockdown-imposed changes in a wastewater treatment plant catchment's socio-demographics impact longitudinal temporal trends in psychoactive pharmaceutical use?

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 876, P. 162342 - 162342

Published: Feb. 25, 2023

Language: Английский

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Investigation of Common Analysis Methods for Detecting Illicit Drugs in Wastewater

Published: April 30, 2025

In this study, research was carried out using analytical devices used to detect illicit drugs that threaten public health. Articles on detecting worldwide were reviewed in the last five years. 2022, one 18 people, or approximately 292 million had past year, and number has increased by more than 20% considering decade. Approximately 30 people amphetamines, 60 opioids year. Drug use, especially opioid remained largest global burden of disease. Wastewater-based epidemiology is an innovative promising discipline recently been for individual biomonitoring estimating amount type drug use population. Many disciplines, including chemistry, physiology, biochemistry, sewage engineering, spatial epidemiology, statistics, pharmaceutical/public health are estimate prevalence their metabolic products wastewater. This study aimed review articles detection wastewater, determine most between 2017-2023, present a summary detection, provide quick overview literature.

Language: Английский

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Assessment of restriction measures implemented during COVID pandemics on community lifestyle choices via wastewater-based epidemiology

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 471, P. 134264 - 134264

Published: April 12, 2024

SARS-CoV-2 pandemic affected lifestyle habits, and the mental health wellbeing of people around world. In this manuscript, two towns (Paulton Radstock) cities (Bath Bristol) in Southwest England (> 1 million people) were monitored for years using Wastewater-Based Epidemiology to assess impacts COVID (including management measures such as lockdowns movement restrictions) on community choices: illicit drugs, legal stimulants, abused pharmaceuticals pain pharma usage. Results triangulated with key dates captured during (national lockdowns, restrictions social distancing measures, etc.). This highlighted a reduction cocaine intake (as benzoylecgonine) (community average: -36 %) first lockdown an increase drugs usage after 3rd national averages amphetamine: +8 %, cocaine/benzoylecgonine: +39 ketamine:+70 when removed, interaction recreational activities increased. There was caffeine 1,7-dimethylxanthine) average:-39 coinciding pubs reopening while nicotine (via cotinine) remained stable indicating lack impact smoking habits. Pain often used resulting from injuries linked sport (naproxen diclofenac) showed decrease due physical exercise access gyms/sport facilities.

Language: Английский

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Preparation of amphiphilic poly(divinylbenzene-co-N-vinylpyrrolidone)-functionalized polydopamine magnetic nanoadsorbents for enrichment of synthetic cannabinoids in wastewater

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(24), P. 3968 - 3982

Published: Jan. 1, 2024

Novel magnetic nanoadsorbents were synthesized and employed as adsorbents for solid-phase extraction of SCs from wastewater matrix within 20 min. Coupled with UHPLC-MS/MS method, nine quantified at trace levels in real wastewater.

Language: Английский

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A magnetic solid phase extraction based on DES/ZIF-MGO coupled with UPLC-MS/MS for the simultaneous detection and consumption evaluation of four illicit drugs

Microchemical Journal, Journal Year: 2024, Volume and Issue: 200, P. 110448 - 110448

Published: March 29, 2024

Language: Английский

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Assessing daily patterns in stimulant use during the COVID-19 pandemic in Melbourne, Australia using wastewater analysis

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 476, P. 135130 - 135130

Published: July 7, 2024

During the COVID-19 pandemic, one of Australia's biggest cities, Melbourne, experienced three major isolation ("lockdown") periods in 2020 (160 days) and 2021 (111 which makes it most locked down cities world-wide. This study assessed how pandemic affected temporal trends methamphetamine, MDMA cocaine consumption using wastewater-based epidemiology. Daily samples were collected for (n = 660 days). Concentrations measured direct-injection LC-MS/MS back-calculated to estimates. Results indicate that methamphetamine use was increasing before first lockdown decreased after end 2020. Methamphetamine appeared have remained steady throughout second period steeply ended. For 2020, steady, with an increase lockdown. start 2021. In comparison less variable stimulant did not appear be as associated restrictions. Overall, this able show impact related social restrictions on illicit use. ENVIRONMENTAL IMPLICATION: Illicit drugs are hazardous chemicals, concern both humans environment. While studies been undertaken understand their trends, work utilizes epidemiology daily sampling provide a comprehensive understanding locked-down world. Understanding consequences significant intervention drug could valuable insights into its potential environmental impact.

Language: Английский

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