The
increasing
number
of
deaths
caused
by
mosquito-borne
diseases
highlights
the
need
to
produce
efficient
and
environmentally
sustainable
alternatives.
aim
present
investigation
we
have
utilized
leaf
from
Laureliopsis
philippiana
(LP)
synthesize
silver
(Ag)
palladium
(Pd)
nanoparticles
(NPs)
studied
toxicity
on
deadly
disease
vectors
larvae
Aedes
aegypti
Anopheles
stephensi.
Biosynthesized
Ag
Pd
NPs
were
investigated
UV-Vis
spectroscopy,
Fourier
transform
infrared
(FT-IR),
X-Ray
Diffraction
(XRD),
Transmission
electron
microscopy
(TEM),
Zeta
potential
analysis.
GC-MS
analysis
L.
assisted
in
identifying
secondary
metabolites
extract's
total
flavonoid
phenolic
compounds,
which
are
reactants
bio-reduction
process
during
production
nanoparticles.
in-silico
was
conducted
mosquito
sterol
carrier
protein-2
(1PZ4)
odorant
binding
protein
(2L2C).
XRD
results
revealed
crystalline
structure
NPs.
At
same
time,
TEM
representation,
biosynthesized
spherical,
clustered,
exhibited
a
noticeable
UV
peak
at
417
370
nm
(average
size
AgNPs:
13.25±
2.53
PdNPs:
4.07±
1.64
nm).
biogenic
concentration-dependent
larvicidal
effect
with
LC50
values
29.596,
17.804,
23.915,
14.878
µg/mL
Ae.
23.946,
13.938,
19.457,
12.876
against
An.
stephensi,
correspondingly.
In-silico
studies
proved
that
Laureliopsine
A
(-7.6
-8.4
kcal/mol)
isoterpinolene
(-7.0
-6.7
showed
significant
docking
scores
comparison
permethrin
(-5.3
-8.0
kcal/mol),
proteins
(1PZ4
2L2C).
Besides,
LP-Ag
non-toxicity
carried
out
Zebrafish
embryos
72h
post-fertilization.
Overall,
findings
clearly
demonstrated
green
synthesized
develop
secure
safe
larvicides.
Indian Journal of Entomology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 21, 2025
The
global
vector
borne
diseases
(VBDs)
that
cause
public
health
problems
such
as
malaria,
dengue,
ZIKA,
Chikungunya,
and
Japanese
Encephalitis.
These
are
not
transmitted
from
human
to
directly
they
require
a
be
transmitted.
When
the
suitable
conditions
met
between
vector,
host
environment
these
effectively.
Vector
disease
very
much
spreading
faster
in
world
recent
years
due
climate
change,
international
trade,
urbanization,
cutting
of
trees
etc.
become
threat
health.
WHO
has
reported
2020
there
were
6,27,000
malaria
deaths
worldwide
241
million
cases.
No
effective
vaccines
or
drugs
available
for
most
example
case
parasite
change
morphology
many
times
with
different
antigens
life
cycle.
As
is
no
treatment
VBDs
only
option
implementation
control
measures.
2017
published
Africa
alone
measures
was
VBDS
663
cases
averted.
For
controlling
pesticides
insect
growth
regulators
use.
Frontiers in Pharmacology,
Journal Year:
2024,
Volume and Issue:
15
Published: Aug. 9, 2024
Malaria
is
one
of
the
most
devastating
diseases
across
globe,
particularly
in
low-income
countries
Sub-Saharan
Africa.
The
increasing
incidence
malaria
morbidity
mainly
due
to
shortcomings
preventative
measures
such
as
lack
vaccines
and
inappropriate
control
over
parasite
vector.
Additionally,
high
mortality
rates
arise
from
therapeutic
failures
poor
patient
adherence
drug
resistance
development.
Although
causative
pathogen
(
Chemistry & Biodiversity,
Journal Year:
2024,
Volume and Issue:
21(4)
Published: Feb. 22, 2024
This
study
is
primarily
focused
on
the
synthesis
of
silver
and
copper
oxide
nanoparticles
utilizing
extract
Ipomoea
staphylina
plant
their
larvicidal
activity
against
specific
larvae.
Notably,
Anopheles
stephensi
Aedes
aegypti
are
significant
disease
vectors
responsible
for
transmitting
diseases
such
as
malaria,
dengue
fever,
Zika
virus,
chikungunya
(Anopheles
stephensi),
(Aedes
aegypti).
These
mosquitoes
have
a
substantial
impact
urban
areas,
influencing
transmission
dynamics.
In
an
effort
to
control
these
larvae,
we
pursued
herbal-based
nanomedicine
derived
from
I.
staphylina,
valuable
herb
in
traditional
medicine.
Our
successful
CuO
followed
environmentally
sustainable
green
chemistry
methodologies.
The
played
dual
role
reducing
agent
dopant,
aligning
with
principles
sustainability.
We
employed
X-ray
diffraction
(XRD)
analysis
validate
nanoparticle
structure
size,
while
field-emission
scanning
electron
microscopy
(FE-SEM)
revealed
well-defined
nanostructures.
Elemental
composition
was
determined
through
energy-dispersive
(EDX)
analysis,
UV-visible
spectroscopy
provided
insights
into
bandgap
energy
(3.15
eV
silver,
1.2
nanoparticles).
exhibited
robust
activity,
surpassing
terms
LC
Journal of Baltic Science Education,
Journal Year:
2024,
Volume and Issue:
23(2), P. 377 - 389
Published: April 20, 2024
Environmental
literacy
related
to
the
utilization
of
medicinal
plants
in
community
provides
a
foundation
for
younger
generation
take
an
active
role
and
form
attitude
care
responsibility
environmental
sustainability.
The
current
research
aims
introduce
Inquiry-Etnobotany
(IEb)
learning
model
enhance
students'
literacy.
design
applied
pretest-posttest
control
group
assess
effectiveness
IEb
intervention,
comparing
it
with
inquiry
discovery
models.
Upon
analysis,
notable
differences
emerged
between
pre-test
post-test
results
across
various
Specifically,
exhibited
substantial
difference,
indicating
significant
progress
student
outcomes.
Similarly,
showcased
improvement,
while
displayed
slightly
smaller
change.
Furthermore,
disparities
outcomes
were
evident
different
schools
involved
study.
has
impact
on
enhancing
However,
each
school
also
demonstrate
that
models
understanding
issues
despite
levels
effect.
Keywords:
model,
ethnobotany,
literacy,
plants,
live
laboratory