Bio‐fabrication and characterization of nano‐silver using Kickxia elatine plant and its anti‐diabetic effect on alloxan‐induced Sprague Dawley rats — An in vivo approach DOI
Noor Ul Huda, Mushtaq Ahmed, Nadia Mushtaq

et al.

Applied Organometallic Chemistry, Journal Year: 2023, Volume and Issue: 38(1)

Published: Nov. 7, 2023

Diabetes mellitus (DM) is one of the most prevalent, fatal, and non‐contagious diseases. Therefore, researchers are making attempts to develop novel anti‐diabetic drugs using various organic compounds biomolecules. The idea nano‐materials as agents seems interesting. current study aims Kickxia elatine (KE) extract‐based nano‐silver (KE‐AgNPs) evaluate their in vivo potency female Sprague Dawley rats. KE‐AgNPs were characterized UV spectroscopy, X‐ray diffractometer (XRD), scanning electron microscopy (SEM), Electron Diffraction Spectroscopy (EDX), Fourier transforms infrared (FTIR) techniques. crystalline nature with a size 42.47 nm confirmed by XRD screening. Spherical‐shaped mono‐dispersed mean 50 validated SEM examination. different phyto‐compounds (tannins, alkaloids, flavonoids, proteins, saponins, phenols, carbohydrates, quinones, sterols, fats, oils) that contribute stabilization reduction FTIR analysis. EDX showed strong peak (3.2 keV) identified Ag main component 61.67% contribution. use Alloxan induce diabetes resulted elevated levels blood sugar, HbA1c, liver, lipid profile, well drastic body weight, organ Hemoglobin. These modifications switched following 21 days treatment diabetic rats, dosage range 150–450 mg kg −1 BW KE extract demonstrated significant inhibition compared untreated group. phytochemical analysis plant was also assessed examine involved potential KE‐AgNPs. findings suggested that, comparison extract, have promising action.

Language: Английский

Larvicidal effects of biofabricated iron nanoparticles made from the aqueous extracts of Eupatorium adenophorum and Artocarpus hirsutus, with their effect on the predatory efficiency of mosquito fish DOI

C.T. Sunila,

V. P. Sylas,

Neethu Cyril

et al.

Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 41, P. 101430 - 101430

Published: Dec. 30, 2024

Language: Английский

Citations

0

Green Synthesis: An Eco-Friendly Route for the Synthesis of Silver and Palladium Nanoparticles Using Laureliopsis Philippiana and Their Toxicity in Mosquitoes and Zebrafish Larvae DOI
Chinnaperumal Kamaraj, Selvam Naveenkumar,

Pradisha Prem

et al.

Published: Jan. 1, 2023

The increasing number of deaths caused by mosquito-borne diseases highlights the need to produce efficient and environmentally sustainable alternatives. aim present investigation we have utilized leaf from Laureliopsis philippiana (LP) synthesize silver (Ag) palladium (Pd) nanoparticles (NPs) studied toxicity on deadly disease vectors larvae Aedes aegypti Anopheles stephensi. Biosynthesized Ag Pd NPs were investigated UV-Vis spectroscopy, Fourier transform infrared (FT-IR), X-Ray Diffraction (XRD), Transmission electron microscopy (TEM), Zeta potential analysis. GC-MS analysis L. assisted in identifying secondary metabolites extract's total flavonoid phenolic compounds, which are reactants bio-reduction process during production nanoparticles. in-silico was conducted mosquito sterol carrier protein-2 (1PZ4) odorant binding protein (2L2C). XRD results revealed crystalline structure NPs. At same time, TEM representation, biosynthesized spherical, clustered, exhibited a noticeable UV peak at 417 370 nm (average size AgNPs: 13.25± 2.53 PdNPs: 4.07± 1.64 nm). biogenic concentration-dependent larvicidal effect with LC50 values 29.596, 17.804, 23.915, 14.878 µg/mL Ae. 23.946, 13.938, 19.457, 12.876 against An. stephensi, correspondingly. In-silico studies proved that Laureliopsine A (-7.6 -8.4 kcal/mol) isoterpinolene (-7.0 -6.7 showed significant docking scores comparison permethrin (-5.3 -8.0 kcal/mol), proteins (1PZ4 2L2C). Besides, LP-Ag non-toxicity carried out Zebrafish embryos 72h post-fertilization. Overall, findings clearly demonstrated green synthesized develop secure safe larvicides.

Language: Английский

Citations

0

Bio‐fabrication and characterization of nano‐silver using Kickxia elatine plant and its anti‐diabetic effect on alloxan‐induced Sprague Dawley rats — An in vivo approach DOI
Noor Ul Huda, Mushtaq Ahmed, Nadia Mushtaq

et al.

Applied Organometallic Chemistry, Journal Year: 2023, Volume and Issue: 38(1)

Published: Nov. 7, 2023

Diabetes mellitus (DM) is one of the most prevalent, fatal, and non‐contagious diseases. Therefore, researchers are making attempts to develop novel anti‐diabetic drugs using various organic compounds biomolecules. The idea nano‐materials as agents seems interesting. current study aims Kickxia elatine (KE) extract‐based nano‐silver (KE‐AgNPs) evaluate their in vivo potency female Sprague Dawley rats. KE‐AgNPs were characterized UV spectroscopy, X‐ray diffractometer (XRD), scanning electron microscopy (SEM), Electron Diffraction Spectroscopy (EDX), Fourier transforms infrared (FTIR) techniques. crystalline nature with a size 42.47 nm confirmed by XRD screening. Spherical‐shaped mono‐dispersed mean 50 validated SEM examination. different phyto‐compounds (tannins, alkaloids, flavonoids, proteins, saponins, phenols, carbohydrates, quinones, sterols, fats, oils) that contribute stabilization reduction FTIR analysis. EDX showed strong peak (3.2 keV) identified Ag main component 61.67% contribution. use Alloxan induce diabetes resulted elevated levels blood sugar, HbA1c, liver, lipid profile, well drastic body weight, organ Hemoglobin. These modifications switched following 21 days treatment diabetic rats, dosage range 150–450 mg kg −1 BW KE extract demonstrated significant inhibition compared untreated group. phytochemical analysis plant was also assessed examine involved potential KE‐AgNPs. findings suggested that, comparison extract, have promising action.

Language: Английский

Citations

0