The impact of COVID-19 pandemic on the incidence of acute gastroenteritis outbreaks in Catalonia (Spain) DOI Creative Commons
Ignasi Parrón,

Mónica Carol,

Núria Bes

et al.

Epidemiology and Infection, Journal Year: 2023, Volume and Issue: 152

Published: Dec. 11, 2023

We carried out a retrospective study of acute gastroenteritis (AGE) outbreaks reported between 1 January 2015 and 31 December 2021 in Catalonia (Spain) to compare the incidence from 2019 with that observed 2020 2021. higher rate during prepandemic period (16.89 outbreaks/1,000,000 person-years) than pandemic (6.96 (rate ratio (RR) 0.41; 95% confidence interval (CI) 0.34 0.51). According aetiology outbreak, those viral decreased 7.82 3.38 person-years (RR 2.31; CI 1.72 3.12), bacterial 5.01 2.78 1.80; 1.29 2.52). There was great reduction AGE Catalonia. This may have been due effect nonpharmaceutical measures applied reduce transmission severe respiratory syndrome coronavirus 2 (SARS-CoV-2), but collapse healthcare system epidemiological surveillance services also had strong influence.

Language: Английский

Beyond COVID-19: Wastewater-based epidemiology for multipathogen surveillance and normalization strategies DOI Creative Commons
Bikash Malla, Sadhana Shrestha, Niva Sthapit

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 174419 - 174419

Published: July 2, 2024

Wastewater-based epidemiology (WBE) is a critical tool for monitoring community health. Although much attention has focused on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative agent of disease 2019 (COVID-19), other pathogens also pose significant health risks. This study quantified the presence SARS-CoV-2, influenza A virus (Inf-A), and noroviruses genogroups I (NoV-GI) II (NoV-GII) in wastewater samples collected weekly (n = 170) from July 2023 to February 2024 five treatment plants (WWTPs) Yamanashi Prefecture, Japan, by quantitative PCR. Inf-A RNA exhibited localized prevalence with positive ratios 59 %–82 % different WWTPs, suggesting regional outbreaks within specific areas. NoV-GI (94 %, 160/170) NoV-GII (100 170/170) were highly prevalent, (6.1 ± 0.8 log10 copies/L) consistently exceeding (5.4 0.7 concentrations. SARS-CoV-2 was detected 100 samples, mean concentrations 5.3 0.5 copies/L WWTP E 5.8 0.4 each WWTPs. Seasonal variability evident, higher all pathogenic viruses during winter. Non-normalized normalized fecal indicator bacteria (Escherichia coli total coliforms), an (pepper mild mottle (PMMoV)), turbidity revealed associations reported cases. + GII showed strong correlations gastroenteritis cases, particularly when E. (Spearman's ρ 0.70–0.81) coliforms (ρ 0.70–0.81), respectively. For non-normalized correlation 0.61, decreasing 0.31 PMMoV, that PMMoV unsuitable. Turbidity normalization yielded suboptimal results. underscored importance selecting suitable parameters tailored accurate trend using WBE, demonstrating its utility beyond COVID-19 surveillance.

Language: Английский

Citations

5
Epidemics and diversity of norovirus variants with acute gastroenteritis outbreak in Hongshan District, Wuhan City, China, 2021-2023 DOI Creative Commons

Dandan Xu,

Jing Li,

Han Ling-yan

et al.

Journal of Infection and Public Health, Journal Year: 2024, Volume and Issue: 17(9), P. 102499 - 102499

Published: July 14, 2024

Norovirus is the predominant pathogen causing foodborne illnesses and acute gastroenteritis (AGE) outbreaks worldwide, imposing a significant disease burden. This study aimed to investigate epidemiological characteristics genotypic diversity of norovirus in Hongshan District, Wuhan City.

Language: Английский

Citations

0
Wastewater-based effective reproduction number and prediction under the absence of shedding information DOI Creative Commons
Hiroki Ando, Kelly A. Reynolds

Environment International, Journal Year: 2024, Volume and Issue: 194, P. 109128 - 109128

Published: Nov. 14, 2024

Estimating effective reproduction number (R

Language: Английский

Citations

0
Viral concentration method biases in the detection of viral profiles in wastewater DOI Creative Commons

Naeema Cheshomi,

Absar Alum,

Matthew F. Smith

et al.

Applied and Environmental Microbiology, Journal Year: 2024, Volume and Issue: 91(1)

Published: Dec. 6, 2024

Viral detection methodologies used for wastewater-based epidemiology (WBE) studies have a broad range of efficacies. The complex matrix and low viral particle load in wastewater emphasize the importance concentration method. This study focused on comparing three commonly virus methods: polyethylene glycol precipitation (PEG), immuno-magnetic nanoparticles (IMNP), electronegative membrane filtration (EMF). Influent effluent samples were processed by methods analyzed DNA/RNA quantification sequencing human viruses. SARS-COV-2, Astrovirus, Hepatitis C detected all both sample types. PEG resulted 20 types viruses influent 16 samples. corresponding number was 21 11 IMNP, 8 EMF. Certain unique to only one For example, six compared which seven type However, EMF method appeared be least effective, detecting none Rotavirus using IMNP method, whereas failed yield similar outcome. Consequently, potential false negative results pose risk credibility WBE applications. Therefore, implementation proper technique is critical minimize biases ensure accurate profiling studies.IMPORTANCEIn recent years, significant research efforts been development methodology studies, showing variability A essential an appropriate evaluation disease prevalence community health such necessitates designing based target pathogenic virus. There remains need comparative performance evaluations context efficiencies. highlights impact matrix, structure, nucleic acid composition efficacy methods. Assessing techniques understanding presence within revealing profiles municipality

Language: Английский

Citations

0
The impact of COVID-19 pandemic on the incidence of acute gastroenteritis outbreaks in Catalonia (Spain) DOI Creative Commons
Ignasi Parrón,

Mónica Carol,

Núria Bes

et al.

Epidemiology and Infection, Journal Year: 2023, Volume and Issue: 152

Published: Dec. 11, 2023

We carried out a retrospective study of acute gastroenteritis (AGE) outbreaks reported between 1 January 2015 and 31 December 2021 in Catalonia (Spain) to compare the incidence from 2019 with that observed 2020 2021. higher rate during prepandemic period (16.89 outbreaks/1,000,000 person-years) than pandemic (6.96 (rate ratio (RR) 0.41; 95% confidence interval (CI) 0.34 0.51). According aetiology outbreak, those viral decreased 7.82 3.38 person-years (RR 2.31; CI 1.72 3.12), bacterial 5.01 2.78 1.80; 1.29 2.52). There was great reduction AGE Catalonia. This may have been due effect nonpharmaceutical measures applied reduce transmission severe respiratory syndrome coronavirus 2 (SARS-CoV-2), but collapse healthcare system epidemiological surveillance services also had strong influence.

Language: Английский

Citations

1