Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 65 - 77
Published: Jan. 1, 2024
Language: Английский
Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 65 - 77
Published: Jan. 1, 2024
Language: Английский
Heliyon, Journal Year: 2024, Volume and Issue: 10(6), P. e27974 - e27974
Published: March 1, 2024
Traditionally, public health surveillance relied on individual-level data but recently wastewater-based epidemiology (WBE) for the detection of infectious diseases including COVID-19 became a valuable tool in arsenal. Here, we use WBE to follow course pandemic Rochester, Minnesota (population 121,395 at 2020 census), from February 2021 December 2022. We monitored impact SARS-CoV-2 infections by comparing three sets data: quantitative measurements viral RNA wastewater as an unbiased reporter virus level community, positive results or antigen tests nasal swabs reflecting community reporting, and hospitalization data. From August 2022 levels were closely correlated with oscillating case numbers. However, September cases remained low numbers dropped, whereas continued oscillate. The reported may reflect virulence reduction combined abated inclination report, divergence shifting endemic. WBE, which also detects asymptomatic infections, can provide early warning impending cases, offers crucial insights during waves transition endemic phase.
Language: Английский
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0Published: Jan. 1, 2024
Language: Английский
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0Published: Jan. 1, 2024
Language: Английский
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0Published: Jan. 1, 2024
Language: Английский
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0Published: Jan. 1, 2024
Language: Английский
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0Published: Jan. 1, 2024
Language: Английский
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0Published: Jan. 1, 2024
Language: Английский
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0medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 16, 2024
Abstract The COVID-19 pandemic highlighted shortcomings in forecasting models, such as unreliable inputs/outputs and poor performance at critical points. As remains a threat, it is imperative to improve current approaches by incorporating reliable data alternative targets better inform decision-makers. Wastewater-based epidemiology (WBE) has emerged viable method track transmission, offering more metric than reported cases for outcomes like hospitalizations. Recognizing the natural alignment of wastewater systems with city structures, ideal leveraging WBE data, this study introduces multi-city, wastewater-based model categorically predict Using hospitalization six US cities, accompanied other epidemiological variables, we develop Generalized Additive Model (GAM) generate two categorization types. Hospitalization Capacity Risk Categorization (HCR) predicts burden on healthcare system based number available hospital beds city. Rate Trend (HRT) trajectory growth rate these categorical thresholds, create probabilistic forecasts retrospectively risk trend category cities over 20-month period 1, 2, 3 week windows. We also propose new methodology measure change points, or time periods where sudden changes outbreak dynamics occurred. explore influence predictor hospitalizations, showing its inclusion positively impacts model’s performance. With study, are able capacity disease trends novel useful way, giving decision-makers tool
Language: Английский
Citations
0Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 65 - 77
Published: Jan. 1, 2024
Language: Английский
Citations
0