Published: Jan. 1, 2025
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(6), P. 3080 - 3080
Published: March 7, 2024
This paper sheds light on the alarming issue of antibiotic resistance (ABR) in aquatic environments, exploring its detrimental effects ecosystems and public health. It examines multifaceted role use aquaculture, agricultural runoff, industrial waste fostering development dissemination resistant bacteria. The intricate interplay between various environmental factors, horizontal gene transfer, bacterial extracellular vesicles (BEVs) accelerating spread ABR is comprehensively discussed. Various BEVs carrying genes like blaCTX-M, tetA, floR, sul/I, as well their contribution to dominance multidrug-resistant bacteria, are highlighted. potential both a threat tool combating explored, with promising strategies targeted antimicrobial delivery systems probiotic-derived EVs holding significant promise. underscores urgency understanding environments. By unraveling these unseen weapons, we pave way for developing effective mitigate ABR, advocating multidisciplinary approach that includes stringent regulations, enhanced wastewater treatment, adoption sustainable practices aquaculture.
Language: Английский
Citations
16
Foods, Journal Year: 2024, Volume and Issue: 13(15), P. 2448 - 2448
Published: Aug. 2, 2024
The application of antimicrobials in aquaculture primarily aims to prevent and treat bacterial infections fish, but their inappropriate use may result the emergence zoonotic antibiotic-resistant bacteria subsequent transmission resistant strains humans via food consumption. aquatic environment serves as a potential reservoir for bacteria, providing an ideal breeding ground development antimicrobial resistance (AMR). mutual inter-connection intensive fish-farming systems with terrestrial environments, processing industry human population creates pathways exacerbating problem further. aim this study was provide overview most effective available risk mitigation strategies tackle AMR aquaculture, based on One Health (OH) concept. stringent guidelines, promoting disease control methods like enhanced farm biosecurity measures vaccinations, alternatives antibiotics (ABs) (prebiotics, probiotics, immunostimulants, essential oils (EOs), peptides phage therapy), feeding practices, genetics, monitoring water quality, improving wastewater treatment, rather than applying excessive antimicrobials, can effectively release into food. contribution traditionally receives less attention, and, therefore, environmental aspects should be included more prominently OH efforts predict, detect risks health. This is particular importance low middle-income countries lack integration national action plans (NAPs) aquaculture-producing environment. Integrated fisheries approach contribute substantial decrease resistance, such case Asia, where percentage compounds exceeding 50% (P50) decreased from 52% 22% within period previous two decades.
Language: Английский
Citations
12
Marine Drugs, Journal Year: 2024, Volume and Issue: 22(4), P. 150 - 150
Published: March 28, 2024
Chitosan (CH) shows great potential as an immunostimulatory feed additive in aquaculture. This study evaluates the effects of varying dietary CH levels on growth, immunity, intestinal morphology, and antioxidant status Nile tilapia (Oreochromis niloticus) reared a biofloc system. Tilapia fingerlings (mean weight 13.54 ± 0.05 g) were fed diets supplemented with 0 (CH0), 5 (CH5), 10 (CH10), 20 (CH20), 40 (CH40) mL·kg−1 for 8 weeks. Parameters assessed after 4 Their final was not affected by supplementation, but at significantly improved gain (WG) specific growth rate (SGR) compared to control (p < 0.05) Skin mucus lysozyme peroxidase activities lower chitosan-treated groups weeks 8. Intestinal villi length width enhanced control. However, caused detrimental impacts muscular layer. especially 5–10 mL·kg−1, increased liver expressions interleukin 1 (IL-1), (IL-8), LPS-binding protein (LBP), glutathione reductase (GSR), (GPX), S-transferase (GST-α) group. Overall, can effectively promote innate capacity systems.
Language: Английский
Citations
10
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159683 - 159683
Published: Jan. 1, 2025
Language: Английский
Citations
1
International Journal of Food Microbiology, Journal Year: 2025, Volume and Issue: 432, P. 111098 - 111098
Published: Feb. 14, 2025
Language: Английский
Citations
1
Aquaculture, Journal Year: 2024, Volume and Issue: 594, P. 741346 - 741346
Published: July 15, 2024
Language: Английский
Citations
8
Aquaculture, Journal Year: 2024, Volume and Issue: 588, P. 740943 - 740943
Published: April 9, 2024
Language: Английский
Citations
6
Reviews in Aquaculture, Journal Year: 2024, Volume and Issue: 16(4), P. 1996 - 2009
Published: June 25, 2024
Abstract This study aimed to conduct a systematic review and meta‐analysis evaluating the inclusion of β‐glucan in aquaculture animal diets its impact on their health outcomes. Relevant studies were identified from Scopus Web Science databases. A total 82 primary published between 1996 2024 reviewed, which 70 included meta‐analysis. The results revealed that application animal's significantly enhanced specific growth rate (SGR; mean effect, g = 2.71; p < 0.001), feed conversion ratio (FCR; −3.88; 0.0001) lowered mortality after exposure pathogens. Likewise, had positive influence ( innate immune parameters (lysozyme phagocyte activity, NBT, ACH50, IgM). found effects β‐glucans varied among marine freshwater fish where fishes 2.05–6.57) exhibit better performance. also negative correlation fish's response trophic level, suggesting with higher levels may be less efficient at absorbing this bio‐stimulant. Even though there high heterogeneity I 2 73%–97%, 0.05) due diversity tested organisms publication bias, our model findings are valid. suggest dietary can have beneficial responses especially for species. validity these observations needs confirmed by further prospective studies.
Language: Английский
Citations
5
Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 64, P. 105642 - 105642
Published: June 15, 2024
Language: Английский
Citations
4
eLife, Journal Year: 2025, Volume and Issue: 13
Published: Jan. 2, 2025
Non-inheritable antibiotic or phenotypic resistance ensures bacterial survival during treatment. However, exogenous factors promoting are poorly defined. Here, we demonstrate that Vibrio alginolyticus recalcitrant to killing by a broad spectrum of antibiotics under high magnesium. Functional metabolomics demonstrated magnesium modulates fatty acid biosynthesis increasing saturated while decreasing unsaturated production. Exogenous supplementation and acids increased decreased susceptibility antibiotics, respectively, confirming the role in resistance. lipidomics revealed glycerophospholipid metabolism is major metabolic pathway remodeled magnesium, where phosphatidylethanolamine reduced phosphatidylglycerol production increased. This process alters membrane composition, polarization, permeability fluidity, thereby reducing uptake V. . These findings suggest presence previously unrecognized mechanism which bacteria escape through use an environmental factor.
Language: Английский
Citations
0