SARS-CoV-2 Antibody Level after Homologous and Heterologous Booster Vaccines: an 18-month Longitudinal Observational Cohort Study in Indonesia

The Open Public Health Journal, Journal Year: 2024, Volume and Issue: 17(1)

Published: July 31, 2024

Background Recently, there have been reports of the rise COVID-19 cases in several sites. The effectiveness vaccine was reported elsewhere. There are still questions on how kinetics antibody response during relatively long periods, need for additional doses, and effect homologous heterologous boosters. study conducted to analyze after primary dose third ChAdOx1 individuals previously receiving two doses [homologous] CoronaVac [heterologous] vaccines. Methods population comprised 52 men 98 women, divided into Recipients first according recommended schedule by Ministry Health Indonesia [MoH].Six months second dose, administered as a booster. levels were measured CMIA method before [time-point or TP1], weeks [TP2], [TP3], 1 month [TP4], 12 [TP5], 18 [TP6] administration. Six Along with these, epidemiological data collected from subjects TP1. Results A total 153 serum samples who had received measured. On TP1, reactivity [the level >50 AU/mL] detected 100 [66,67%] subjects, indicating possible previous exposure SARS-CoV-2. TP2, sharp increase documented group. However, following cohort, gap narrowing, TP6, showed no significant difference between groups [p>0.05]. Likewise, differences shown without history TP1 Considering characteristics, based sex, age groups, BMI level. Conclusion This provides deeper understanding longitudinally among those SARS CoV-2 infection, recipients different vaccines, It is necessary elucidate further next reflects neutralizing an indicator protection against infection risk.

Language: Английский

An integrative analysis of SARS-CoV 2 during the first and second waves of COVID-19 in Salta, Argentina

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 955, P. 176782 - 176782

Published: Oct. 6, 2024

Language: Английский