Comprehensive review of patients with hypercoagulable state in rheumatoid arthritis and strategies to reduce readmission rates: A retrospective cohort study based on protective exploration of traditional Chinese medicine DOI Creative Commons
Yang Li, Jian Liu, Yuedi Hu

et al.

Medicine, Journal Year: 2024, Volume and Issue: 103(50), P. e40890 - e40890

Published: Dec. 13, 2024

This study aimed to investigate the effect of traditional Chinese medicine (TCM) intervention on risk readmission and laboratory indicators in patients with rheumatoid arthritis hypercoagulable state. In retrospective cohort design, RA hospitalized between June 2013 2021 at First Affiliated Hospital Anhui University Medicine were followed up by telephone. Propensity score matching (PSM) was used balance deviations baseline information (HC) non-hypercoagulable (Non-HC) groups, exposure defined as receiving TCM treatment for ≥ 1 month. Cox proportional hazards model Kaplan–Meier survival curves employed determine factors influencing RA-HC patients. Mantel test association rule analysis explore relationship included indicators. A total 1169 cases successfully up, including 831 1:2 PSM yielded 311 non-HC group versus 535 HC group. We observed that incidence surgical significantly higher than group, while readmission, treatment, all-cause mortality much lower exposed non-exposed (all P < .05). Based model, we identified age above 60 years, Sjogren’s syndrome, neutrophil count, neutrophil-lymphocyte ratio (NLR) playing a protective role. The further showed high-exposure subgroup markedly low-exposure subgroup. Furthermore, highlights an intrinsic correlation coagulation markers other such erythrocyte sedimentation rate (ESR) hypersensitive c-reactive protein (hs-CRP), which are dramatically influenced gender, age, etc. addition, revealed strong non-readmission, well improvement factor, hs-CRP, ESR, platelet NLR As promising therapeutic strategy, sufficient intensity duration interventions can effectively reduce relieve

Language: Английский

Urbanization alters the diversity, assembly, and complexity in microbial communities of a subtropical river system DOI
Teng Zhao, Yuting Deng,

Ling Zhou

et al.

Hydrobiologia, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Language: Английский

Citations

0
The shifts in microbial interactions and gene expression caused by temperature and nutrient loading influence Raphidiopsis raciborskii blooms DOI
Baohai Zheng,

Ling Zhou,

Jinna Wang

et al.

Water Research, Journal Year: 2024, Volume and Issue: 268, P. 122725 - 122725

Published: Oct. 31, 2024

Language: Английский

Citations

3
Insights into cyanobacterial blooms through the lens of omics DOI Creative Commons
Ve Van Le, Quynh-Giao Tran, So-Ra Ko

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 934, P. 173028 - 173028

Published: May 7, 2024

Cyanobacteria are oxygen-producing photosynthetic bacteria that convert carbon dioxide into biomass upon exposure to sunlight. However, favorable conditions cause harmful cyanobacterial blooms (HCBs), which the dense accumulation of at water surface or subsurface, posing threats freshwater ecosystems and human health. Understanding mechanisms underlying bloom formation is crucial for effective management. In this regard, recent advancements in omics technologies have provided valuable insights HCBs, raised expectations develop more control methods near future. This systematic literature review aims present genomic architecture, adaptive mechanisms, microbial interactions, ecological impacts HCBs through lens omics. Genomic analysis indicates genome plasticity cyanobacteria has enabled their resilience adaptation environmental changes. Transcriptomic investigations revealed use various strategies adapting stress. Additionally, metagenomic metatranscriptomic analyses emphasized significant role community regulating HCBs. Finally, we offer perspectives on potential opportunities further research field.

Language: Английский

Citations

2
Urbanization alters the diversity, assembly and complexity in microbial generalist and specialist community of a subtropical river system DOI Creative Commons
Teng Zhao, Yuting Deng,

Ling Zhou

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: June 17, 2024

Abstract Urbanization-induced environmental changes are becoming a major threat to river systems. However, little is known about how urbanization affects aquatic microbial communities despite their critical role in maintaining ecological processes and nutrient cycling. Here, we investigated assembly of habitat generalists specialists different stages subtropical rivers. The results highlight that nitrogen compounds can influence the composition community. Proteobacteria Bacteroidetes, as well Cyanobacteria were identified dominant phyla Both total diversity species richness significantly higher than specialists, while beta was low-level rivers (LUS) high-level (HUS). For generalist, heterogeneous selection most important process for HUS winter, but dispersal limitation, drift other nondominated mainly establishment LUS whether summer or winter. Similarly, stochastic main HUS, In winter LUS, more complex network found stronger complexity robustness co-occurrence compared HUS. Overall, these suggest play key shaping urbanization-induced homogenization communities. insights gained from this study may be helpful understanding mechanisms.

Language: Английский

Citations

1
Bacterial and Archaeal Communities in Erhai Lake Sediments: Abundance and Metabolic Insight into a Plateau Lake at the Edge of Eutrophication DOI Creative Commons
Zhen Xie,

Wei Li,

Kaiwen Yang

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(8), P. 1617 - 1617

Published: Aug. 8, 2024

The littoral zones of lakes are potential hotspots for local algal blooms and biogeochemical cycles; however, the microbial communities within sediments eutrophic plateau remain poorly understood. Here, we investigated taxonomic composition, co-occurrence networks, functional roles both abundant rare taxa bacterial archaeal communities, as well physicochemical parameters, in from Erhai Lake, a mesotrophic lake transitioning towards eutrophy located Yunnan-Guizhou Plateau. 16S rRNA gene sequencing revealed that were dominated by Proteobacteria, Bacteroidetes, Chloroflexi, while Euryarchaeota was main phylum. Co-occurrence network analysis keystone mainly belonged to species domain, but over half species, demonstrating their fundamental persistence. contributed substantially overall abundance (81.52%), whereas smaller subset accounted up 82.70% abundance. Functional predictions highlighted divergence metabolic potentials, with sub-communities enriched pathways nitrogen cycling, sulfur chlorate reduction, linked carbon cycling processes such methanotrophy. Abundant exhibited high methanogenesis, chemoheterotrophy, dark hydrogen oxidation. Spearman correlation showed genera

Language: Английский

Citations

0
Benthic Microbes on the Shore of Southern Lake Taihu Exhibit Ecological Significance and Toxin-Producing Potential Through Comparison with Planktonic Microbes DOI Open Access

Qihang Zhao,

Bin Wu, Jun Zuo

et al.

Water, Journal Year: 2024, Volume and Issue: 16(21), P. 3155 - 3155

Published: Nov. 4, 2024

Water quality and aquatic ecosystems along lakeshores are vital for ecological balance human well-being. However, research has primarily focused on plankton, with benthic niches being largely overlooked. To enhance understanding of microbial communities, we utilized 16S 18S rRNA sequencing alongside multivariate statistical methods to analyze samples from the shoreline Lake Taihu in Huzhou City, Zhejiang Province. Our results reveal a marked difference species composition between planktonic microorganisms, cyanobacteria predominantly comprising filamentous genera like Tychonema, while 95% were Cyanobium. The β-diversity microorganisms was notably higher than that counterparts. neutral community model indicated stochastic processes dominated assembly, deterministic prevailed communities. Null models showed homogeneous selection influenced whereas communities affected by undominated dispersal limitation. Network analysis networks more stable networks. Importantly, dominant cyanobacterial posed potential toxin risks, highlighting need enhanced monitoring risk assessment. Overall, these findings our offer valuable insights assessment management eutrophicated environments.

Language: Английский

Citations

0
Impact of turbidity, temperature, and total nitrogen on cyanobacterial blooms in Lake Ypacaraí (Paraguay) DOI Creative Commons

Claudia Raquel Ávalos,

Gabriela Gutiérrez Sosa,

Gustavo René Brozón

et al.

Case Studies in Chemical and Environmental Engineering, Journal Year: 2024, Volume and Issue: unknown, P. 101027 - 101027

Published: Nov. 1, 2024

Language: Английский

Citations

0
Comprehensive review of patients with hypercoagulable state in rheumatoid arthritis and strategies to reduce readmission rates: A retrospective cohort study based on protective exploration of traditional Chinese medicine DOI Creative Commons
Yang Li, Jian Liu, Yuedi Hu

et al.

Medicine, Journal Year: 2024, Volume and Issue: 103(50), P. e40890 - e40890

Published: Dec. 13, 2024

This study aimed to investigate the effect of traditional Chinese medicine (TCM) intervention on risk readmission and laboratory indicators in patients with rheumatoid arthritis hypercoagulable state. In retrospective cohort design, RA hospitalized between June 2013 2021 at First Affiliated Hospital Anhui University Medicine were followed up by telephone. Propensity score matching (PSM) was used balance deviations baseline information (HC) non-hypercoagulable (Non-HC) groups, exposure defined as receiving TCM treatment for ≥ 1 month. Cox proportional hazards model Kaplan–Meier survival curves employed determine factors influencing RA-HC patients. Mantel test association rule analysis explore relationship included indicators. A total 1169 cases successfully up, including 831 1:2 PSM yielded 311 non-HC group versus 535 HC group. We observed that incidence surgical significantly higher than group, while readmission, treatment, all-cause mortality much lower exposed non-exposed (all P < .05). Based model, we identified age above 60 years, Sjogren’s syndrome, neutrophil count, neutrophil-lymphocyte ratio (NLR) playing a protective role. The further showed high-exposure subgroup markedly low-exposure subgroup. Furthermore, highlights an intrinsic correlation coagulation markers other such erythrocyte sedimentation rate (ESR) hypersensitive c-reactive protein (hs-CRP), which are dramatically influenced gender, age, etc. addition, revealed strong non-readmission, well improvement factor, hs-CRP, ESR, platelet NLR As promising therapeutic strategy, sufficient intensity duration interventions can effectively reduce relieve

Language: Английский

Citations

0