Impact of urinary PAHs on psoriasis risk in U.S. adults: Insights from NHANES DOI Creative Commons

Jiang-Hui Li,

Xiaoning Yan, Jiaying Fu

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314964 - e0314964

Published: Dec. 5, 2024

Objective Exposure to environmental pollutants is increasingly recognized as a risk factor for the development of psoriasis. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in air and might induce reactions such oxidative stress. Nevertheless, it still unclear if PAHs have any influence on prevalence psoriasis over entire population United States. The objective this study was assess association between urine Methods research included 3,673 individuals aged 20 years or older who participated 2003–2006 2009–2012 National Health Nutrition Examination Surveys (NHANES). We employed logistic regression models evaluate relationship levels PAH metabolites smoothed curve fitting illustrate concentration-response relationship. Additionally, subgroup interaction analyses were conducted elucidate these associations. Furthermore, we weighted quartile sum (WQS) regressions examine distinct effects individual mixed However, important note that NHANES sample may be subject selectivity self-reporting bias, which data’ generalisability. Results observed highest tertiles 2-NAP 2-FLU had 63% (95% CI 1.02, 2.61) 83% 1.14, 2.96) higher odds with prevalence, respectively. Meanwhile, tertile 2 3 3-PHE also significantly associated psoriasis, 65% 1.01, 2.69) 14% 1.17, 3.00), revealed significant correlation specific groups, including males, 40–60 years, BMI > 30, those hyperlipidemia. In WQS model, positive found combination (OR 1.43, 95% 1.11, 1.84), being most prevalent component across all mixtures (0.297). Conclusions Our findings indicate adults. Among metabolites, demonstrated prominent impact. Controlling exposure, an strategy minimizing exposure contaminants lowering critical raising public knowledge about health preserving health.

Language: Английский

Occurrence and distribution of PAHs in the Yangtze River and urban river waters of Nanjing, China: insights from in situ DGT measurements DOI Creative Commons

Qiuyu Rong,

Hao Zhang, Yanying Li

et al.

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 125921 - 125921

Published: Feb. 1, 2025

Language: Английский

Citations

1
Distribution, levels, sources and risk assessment of polycyclic aromatic hydrocarbons in the bottom sediments of a Mediterranean river under multiple anthropopressures (Soummam River), Algeria DOI
Lydia Bensadi,

Moufok Azzoug,

Abdelhakim Benslimane

et al.

Marine Pollution Bulletin, Journal Year: 2024, Volume and Issue: 202, P. 116416 - 116416

Published: April 25, 2024

Language: Английский

Citations

3
Human Exposure Estimation of Polycyclic Aromatic Hydrocarbons (PAHs) Resulting from Bucharest Landfill Leakages DOI Open Access

Alexandru Balint,

Ecaterina Matei, Maria Râpă

et al.

Sustainability, Journal Year: 2025, Volume and Issue: 17(4), P. 1356 - 1356

Published: Feb. 7, 2025

This paper focuses on identifying the human health risks as a result of presence polycyclic aromatic hydrocarbons (PAHs) in groundwater due to Bucharest landfill leakages. The main subjects were neighboring areas receptors. functional located near capital Romania was selected case study. Fluorene (Pf), phenanthrene (Phe), anthracene (Ant), fluoranthene (Flu) and pyrene (Pyr) detected using gas chromatography-tandem mass spectrometry (GC-MS/MS) analysis. for receptors via ingestion dermal exposure scenarios developed considering contact once per day during showering 20 min regular most contaminated with PAHs at rate 2 L day. concentration ranges wer <0.0010–0.0037 μg L−1 Pf, 0.0014–0.0065 Phe, <0.0010–0.0013 Ant, <0.0010–0.0011 Flu, 0.0030–0.0032 Pyr. rest under limit detection. Both cumulative hazard risk quotient are well below value 1, which indicates significant low PAH-contaminated groundwater. However, daily consumption skin is minimal.

Language: Английский

Citations

0
PAH Contamination, Sources and Health Risks in Black Soil Region of Jilin Province, China DOI Creative Commons

Guzailinuer Aihemaitijiang,

Lujuan Zhang,

Mingtang Li

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(12), P. 937 - 937

Published: Dec. 23, 2024

Soils in the Black Soil Zone of northeast China are experiencing pollution from polycyclic aromatic hydrocarbons (PAHs) as region undergoes urbanization. In this study, 119 topsoil samples were collected black soil agricultural area Jilin Province, to investigate characteristics and spatial distribution 16 PAHs. The total concentration ∑16 PAHs soils ranged 2.546 33.993 mg/kg, with a mean value 9.99 mg/kg. Positive matrix factorization (PMF) analysis indicated that vehicle exhaust oil combustion identified main contributors traffic- energy-related pollution. inherited lifetime carcinogenicity risk (ILCR) was found be relatively low, indicating low potential region, adults (1.34 × 10-5) exhibiting higher than adolescents (8.62 10-6) children (7.49 10-6). highest values for intake, skin contact, inhalation routes observed adult group, suggesting residents certain areas may at increased health risk. This study enhances our understanding pathways through which enter Province provides insights could aid addressing PAH soil, ultimately contributing more sustainable practices region.

Language: Английский

Citations

1
Impact of urinary PAHs on psoriasis risk in U.S. adults: Insights from NHANES DOI Creative Commons

Jiang-Hui Li,

Xiaoning Yan, Jiaying Fu

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314964 - e0314964

Published: Dec. 5, 2024

Objective Exposure to environmental pollutants is increasingly recognized as a risk factor for the development of psoriasis. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in air and might induce reactions such oxidative stress. Nevertheless, it still unclear if PAHs have any influence on prevalence psoriasis over entire population United States. The objective this study was assess association between urine Methods research included 3,673 individuals aged 20 years or older who participated 2003–2006 2009–2012 National Health Nutrition Examination Surveys (NHANES). We employed logistic regression models evaluate relationship levels PAH metabolites smoothed curve fitting illustrate concentration-response relationship. Additionally, subgroup interaction analyses were conducted elucidate these associations. Furthermore, we weighted quartile sum (WQS) regressions examine distinct effects individual mixed However, important note that NHANES sample may be subject selectivity self-reporting bias, which data’ generalisability. Results observed highest tertiles 2-NAP 2-FLU had 63% (95% CI 1.02, 2.61) 83% 1.14, 2.96) higher odds with prevalence, respectively. Meanwhile, tertile 2 3 3-PHE also significantly associated psoriasis, 65% 1.01, 2.69) 14% 1.17, 3.00), revealed significant correlation specific groups, including males, 40–60 years, BMI > 30, those hyperlipidemia. In WQS model, positive found combination (OR 1.43, 95% 1.11, 1.84), being most prevalent component across all mixtures (0.297). Conclusions Our findings indicate adults. Among metabolites, demonstrated prominent impact. Controlling exposure, an strategy minimizing exposure contaminants lowering critical raising public knowledge about health preserving health.

Language: Английский

Citations

0