Glycolipid Metabolic Disorders, Metainflammation, Oxidative Stress, and Cardiovascular Diseases: Unraveling Pathways

Biology, Journal Year: 2024, Volume and Issue: 13(7), P. 519 - 519

Published: July 12, 2024

Glycolipid metabolic disorders (GLMDs) are various resulting from dysregulation in glycolipid levels, consequently leading to an increased risk of obesity, diabetes, liver dysfunction, neuromuscular complications, and cardiorenal vascular diseases (CRVDs). In patients with GLMDs, excess caloric intake a lack physical activity may contribute oxidative stress (OxS) systemic inflammation. This study aimed review the connection between GLMD, OxS, metainflammation, onset CRVD. GLMD is due causing dysfunction synthesis, breakdown, absorption glucose lipids body, excessive ectopic accumulation these molecules. mainly neuroendocrine dysregulation, insulin resistance, metainflammation. many inflammatory markers defense cells play vital role related tissues organs, such as blood vessels, pancreatic islets, liver, muscle, kidneys, adipocytes, promoting lesions that affect interconnected organs through their signaling pathways. Advanced glycation end products, ATP-binding cassette transporter 1, Glucagon-like peptide-1, Toll-like receptor-4, sphingosine-1-phosphate (S1P) crucial since they glucolipid metabolism. The consequences this system organ damage morbidity mortality.

Language: Английский

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An AI-driven strategy for active compounds discovery and non-destructive quality control in traditional Chinese medicine: a case of Xuefu Zhuyu Oral Liquid

Talanta, Journal Year: 2025, Volume and Issue: unknown, P. 127627 - 127627

Published: Jan. 1, 2025

Language: Английский

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Developmental and neurotoxic effects of dimethyl phthalate on zebrafish embryos and larvae

Aquatic Toxicology, Journal Year: 2025, Volume and Issue: 279, P. 107241 - 107241

Published: Jan. 6, 2025

Language: Английский

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Innovative N-butyryl-L-homoserine lactones-assisted strategy for phytoremediation: Improving soybean growth and soil quality in dimethyl phthalate remediation

Process Safety and Environmental Protection, Journal Year: 2025, Volume and Issue: unknown, P. 106882 - 106882

Published: Feb. 1, 2025

Language: Английский

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Climate change versus Mediterranean diet: A hazardous struggle for the women's heart

American Heart Journal Plus Cardiology Research and Practice, Journal Year: 2024, Volume and Issue: 45, P. 100431 - 100431

Published: July 29, 2024

Climate change impacts food systems, causing nutritional deficiencies and increasing cardiovascular diseases (CVD). Regulatory frameworks like the European Farm-to-Fork Strategy aim to mitigate these effects, but current EU safety regulations inadequately address health risks from poor diet quality contaminants. adversely affects quality, such as nutrient depletion in crops due higher CO

Language: Английский

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Unravelling the developmental toxicity of heavy metals using zebrafish as a model: a narrative review

BioMetals, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

Language: Английский

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A comprehensive review of the calcium dynamics of environmental pollutants in human health: insights from zebrafish models

Molecular & Cellular Toxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Language: Английский

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ADB-FUBINACA-induced developmental toxicity, neurotoxicity, and cardiotoxicity in embryonic zebrafish (Danio rerio)

Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 121517 - 121517

Published: April 1, 2025

Language: Английский

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Environmental endocrine disrupting chemical 4-tert-butylphenol induced calcium overload and subsequent autophagy impairment via miRNA-363/CACNA1D Axis in epithelioma papulosum cyprini cells

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2024, Volume and Issue: 283, P. 109968 - 109968

Published: June 28, 2024

Language: Английский

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