Unveiling the Hidden Threat: Per- and Polyfluoroalkyl Substance Pollution’s Distinct Traits and Crucial Impacts on Lung Function in Chinese Plateau Populations
Li He,
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Ce Liu,
No information about this author
Hao Zhao
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et al.
Environment & Health,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 14, 2025
Language: Английский
Supramolecular solvent extraction of drugs and pharmaceuticals in indoor dust from public buildings
The Science of The Total Environment,
Journal Year:
2025,
Volume and Issue:
968, P. 178859 - 178859
Published: Feb. 18, 2025
Language: Английский
Family-based exposure assessment of legacy and alternative poly- and perfluoroalkyl substances (PFASs) by multiple pathways
Hye Kyung Jeon,
No information about this author
Mi-Yeon Shin,
No information about this author
Won‐Young Kim
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et al.
The Science of The Total Environment,
Journal Year:
2025,
Volume and Issue:
969, P. 178735 - 178735
Published: Feb. 27, 2025
Language: Английский
A randomized controlled trial of a housing intervention to reduce endocrine disrupting chemical exposures in children
Environment International,
Journal Year:
2024,
Volume and Issue:
191, P. 108994 - 108994
Published: Aug. 30, 2024
Few
studies
have
considered
household
interventions
for
reducing
endocrine
disrupting
chemical
(EDC)
exposures.
We
conducted
a
secondary
analysis
of
randomized
controlled
trial,
originally
designed
to
reduce
lead
exposure,
evaluate
if
the
intervention
lowered
EDC
exposures
in
young
children.
Study
participants
were
children
from
Cincinnati,
Ohio
area
(n
=
250,
HOME
Study).
Prenatally,
families
received
housing
that
included
paint
stabilization
and
dust
mitigation,
or
as
control,
injury
prevention
measures.
At
24-months,
we
measured
organophosphate
esters
(OPEs)
phthalates
their
metabolites
urine.
perfluoroalkyl
substances
(PFAS)
serum
at
24-
36-months,
respectively.
assessed
associations
between
biomarker
EDCs
using
Spearman
correlations,
characterized
mixtures
via
principal
components
analysis,
investigated
treatment
effects
linear
regression.
To
mitigate
selection
bias,
fit
statistical
models
inverse
probability
retention
weights.
Correlations
analogous
biomarkers
weak-to-moderate
(ρ's
≤
0.3).
The
was
associated
with
23
%
(95
CI:
-38,
-3)
lower
urinary
DEHP
and,
per-protocol
34
-55,
-2)
MBZP.
Additionally,
among
Black
African
American
children,
concentrations
several
PFAS
(e.g.,
-42
%;
95
-63,
-8
PFNA).
Household
include
mitigation
may
childhood
some
Blacks/African
Americans.
These
findings
highlight
need
larger
tailored
sustained
interventions.
Language: Английский
Analysis of oral and inhalation toxicity of per- and polyfluoroalkylated organic compounds in rats and mice using multivariate QSAR
SAR and QSAR in environmental research,
Journal Year:
2024,
Volume and Issue:
35(10), P. 877 - 897
Published: Oct. 2, 2024
Per-
and
polyfluoroalkylated
organic
compounds
(PFAs)
are
versatile
extensively
used
in
global
industries.
However,
they
also
persistent
pollutants
(POPs).
This
study
aimed
to
develop
new
models
for
assessing
oral
inhalation
toxicity
rat
mice
models.
A
set
of
407
PFAs
from
the
literature
was
divided
into
four
groups
based
on
endpoints
interest.
The
were
constructed
using
only
2D
structure
descriptors
derived
SMILES
strings.
resulting
showed
a
strong
statistical
quality
all
endpoints.
They
present
an
applicability
domain
(AD)
that
ensures
good
reliability,
provided
meaningful
interpretation,
which
partially
supported
by
existing
literature.
Consequently,
these
valuable
understanding
how
exert
their
toxic
effect
mammals
predicting
risk
associated
with
significant
industrial
chemical
agents.
Language: Английский
PFOA, PFOS and PFHxS toxicokinetic considerations for the development of an in vivo approach for assessing PFAS relative bioavailability in soil
Environment International,
Journal Year:
2024,
Volume and Issue:
195, P. 109232 - 109232
Published: Dec. 20, 2024
Language: Английский