IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 2, 2024
Multidimensional separation systems offer several advantages over traditional one-dimensional systems, particularly their ability to separate molecules from complex mixtures. Two-dimensional liquid chromatography (2D-LC) significantly enhances the analyze mixtures by providing greater power, sensitivity, and flexibility, making it an invaluable tool for metabolomics research. The 2D-LC is exciting mode when pursuing untargeted analysis, as allows high-resolution subsequent identification quantification of more analytes. This chapter summarizes current applications in setups different modes that are being employed, presenting most suitable combinations chromatographic methods targeted applications.
Language: Английский