سپیدهدم., Journal Year: 2024, Volume and Issue: 6(1), P. 32 - 42
Published: June 1, 2024
Language: Английский
ACS Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 10, 2025
Yam (Dioscorea opposita Thunb.) is cultivated as one of the staple food crops, and its edible tubers are found to contain various bioactive substances, especially so-called soluble nondigestible yam polysaccharides (YPs). However, whether covalent Se-grafting YP could lead changed antioxidant hypoglycemic activities remains unknown. YPs were thus separated from fresh Chinese using water extraction enzymatic treatment then chemically selenized yield two products, namely, YPSe-I YPSe-II. These products acquired in form selenite had different Se contents (0.795 1.48 versus 0.035 g/kg) or selenization extents. The results obtained determination capacity indicated that Se-grafted possessed a higher activity compared because they more effective scavenging both OH ABTS radicals reducing Fe3+ Fe2+. Meanwhile, YPSe-II, than inhibit digestive enzymes, α-amylase α-glucosidase. derived cell experiments YP, YPSe-I, YPSe-II not cytotoxic normal BRL-3A liver cells established insulin-resistant cells. particularly exhibited effect model was resulting increased glucose consumption enhanced oxidase superoxide dismutase, catalase, glutathione peroxidase. Data comparison also manifested consistently demonstrated YPSe-I. It concluded high extent endowed with beneficial functions, such effect. this potentially serve suitable chemical approach modify functions natural polysaccharides.
Language: Английский
Citations
1
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137143 - 137143
Published: Nov. 3, 2024
Language: Английский
Citations
7
Food & medicine homology., Journal Year: 2024, Volume and Issue: 1(2), P. 9420017 - 9420017
Published: Aug. 12, 2024
Emilia prenanthoidea DC. (EP) is a medicinal plant that belongs to the tribe Emilia Cass in family Asteraceae. Although it has long history of use, there are few research reports on this herb. In study, for first time, ultrasound-assisted extraction (UAE) conditions were optimized by response surface methodology (RSM) extract total flavonoids from EP. An method was used determine flavonoid content (TFC) and antioxidant activity EP extracts 12 regions Guizhou, China. Combining environmental factors regions, effects different growth environments TFC analyzed. work, proven optimal solvent concentration 45%, an ultrasonication time 25 min, liquid-solid ratio 46.25 mL/g. Under condition, highest (41.182 mg/g) found Daping, while lowest (28.865 Liping. Evaluation showed capacity followed Tuan Shan, Yaobai Green Lake. Ecological affected both Annual sunshine hours had significant effect (r = −0.841, P < 0.01). conclusion, study established effective EP, natural antioxidant. The environment also It provides experimental basis extensive utilization
Language: Английский
Citations
5
Marine Drugs, Journal Year: 2024, Volume and Issue: 22(8), P. 356 - 356
Published: Aug. 2, 2024
Chlamydomonas reinhardtii polysaccharides (CRPs) are bioactive compounds derived from C. reinhardtii, yet their potential in cancer therapy remains largely unexplored. This study optimized the ultrasound-assisted extraction conditions using response surface methodology and proceeded with isolation purification of these polysaccharides. The optimal were identified as a sodium hydroxide concentration 1.5%, ultrasonic power 200 W, solid-to-liquid ratio 1:25 g/mL, an treatment time 10 min, water bath duration 2.5 h, yielding actual rate 5.71 ± 0.001%, which closely aligns predicted value 5.639%. Infrared analysis revealed that CRP-1 CRP-2 α-pyranose structures containing furoic acid, while CRP-3 CRP-4 β-pyranose acid. Experimental results demonstrated all four purified inhibited proliferation cervical (HeLa) hepatoma (HepG-2) colon (HCT-116) cells, showing most significant inhibitory effect on cancer, achieving inhibition rates 60.58 0.88% 40.44 1.44%, respectively, significantly reducing migration HeLa cells. DAPI staining confirmed inhibit cell by inducing apoptosis has liver not only elucidates application but also provides scientific basis for further development utilization.
Language: Английский
Citations
4
Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100713 - 100713
Published: Feb. 1, 2025
Language: Английский
Citations
0
Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)
Published: March 9, 2025
Language: Английский
Citations
0
Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16
Published: March 13, 2025
Zanthoxylum bungeanum residue has attracted increasing attention owing to its antibacterial effect, which presents potential as novel antimicrobial agents for the management of algal blooms. In this study, ability Z. extract control blooms been firstly verified. Then, response surface methodology was employed optimize flavonoids yield, primary component in extract, and underlying photosynthetic inhibition mechanisms on Tetrodesmus obliquus investigated. Results showed that highest yield total increased 4.08% when extraction conditions were a liquid-to-solid ratio 10:1, ethanol concentration 60%, temperature 80°C, time 30 min. Meanwhile, treatment with at doses 40.0 mg/L significantly decreased Fv/Fm PIabs values T. by 24.36 88.87% 50 h, respectively. The added induced damage multiple levels physiological biochemical processes cells, including reduced electron transport capability, disrupted energy transfer photosystem II, disruption OEC structure, altered distribution PSII reaction center. To our knowledge, study first verification residue’s algicidal potential, these findings contribute deeper understanding allelopathic offer valuable insights
Language: Английский
Citations
0
Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 760 - 760
Published: March 27, 2025
Zanthoxylum bungeanum leaves were regarded as a waste byproduct for long period of time, yet their functional components presented potential novel antimicrobial agents. However, effectiveness in controlling algal blooms remains unexplored. In this study, the inhibition effect Z. leaf extracts on was firstly demonstrated, and flavonoid profiles extract identified using non-targeted metabolomics analysis. Then, response surface methodology performed extraction to further evaluate feasibility industrial application. Specifically, effects cell density, photosynthetic efficiency, antioxidant activity Tetrodesmus obliquus investigated. The results showed that yield flavonoids from reached 6.85% under optimized conditions an ultrasonic power 600 W, LSR 20:1 mL/g, ethanol concentration 77.5%, duration 18 min, temperature 80 °C, which significantly decreased Fv/Fm PIabs values by 54.60% 98.22%, respectively, after exposure T. 40.0 mg/L 66 h. Meanwhile, treatment with at dose generated T-AOC 4.0 times higher than control without addition extracts. These suggest could be used development potentially effective biological algicides. Our study provides data support algicides realizes resource application waste, achieving synergistic outcome both economic ecological benefits.
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142708 - 142708
Published: March 1, 2025
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143417 - 143417
Published: April 1, 2025
Language: Английский
Citations
0