Association between exposure to per- and polyfluoroalkyl substances (PFAS) and chronic cough in American adults: Results from NHANES 2003–2012

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117901 - 117901

Published: Feb. 1, 2025

Chronic cough, which affects approximately 10 % of the global population, is recognized as a significant health issue, especially among females. Recent research suggests that chronic cough may be an independent disease rather than merely symptom other conditions. This study focuses on potential role exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS) in development noting PFAS has been linked various adverse outcomes. We aimed explore association between risk U.S. analyzing data from National Health Nutrition Examination Survey (NHANES) 2003 2012 examining sex-based differences. Our findings reveal several factors independently associated with increased incidence including elevated levels serum perfluorobutane sulfonic acid (PFBS) perfluoroheptanoic (PFHP). The multi-pollutant models consistently demonstrated positive correlation higher adult males, PFBS PFHP primary contributors. However, due cross-sectional design NHANES study, further necessary elucidate precise mechanisms by contribute cough.

Language: Английский

New insights into the effects of PFOS exposure on rat lung development: morphological, functional, and single-cell sequencing analysis

Archives of Toxicology, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Language: Английский