Beyond Traditional Lateral Flow Assays: Enhancing Performance Through Multianalytical Strategies

Biosensors, Journal Year: 2025, Volume and Issue: 15(2), P. 68 - 68

Published: Jan. 23, 2025

Multiplex lateral flow assays are one of the greatest advancements in world rapid diagnostics, achieving performance several tests one. These meet basic requirements increasing ease use, low detection limit, and high specificity, as they combine use novel strategies, such exploitation multiple labels, a variety amplification methods. have proven their usefulness many different areas, including clinical food, environmental monitoring. In this review paper, we attempt to highlight discuss predominant changes multianalyte LFAs, related principle, development, combination with other Attention is paid flexibility challenges associated LFA arrays, strategies improve detectability, sensitivity, reliability assays. Therefore, emphasizes current advances field underline possible impact multiplex LFAs on future diagnostics analytical sciences.

Language: Английский

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Incorporating deep learning into smartphone-assisted sensing platform based on N, B-CDs for quantitative visual detection of silver ion

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 112782 - 112782

Published: Jan. 1, 2025

Language: Английский

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Immunochromatographic food control tools: New developments and practical prospects

Theory and practice of meat processing, Journal Year: 2025, Volume and Issue: 9(4), P. 280 - 295

Published: Jan. 20, 2025

In the modern food production technologies, tools and means of simple rapid testing raw materials, intermediate products final ready-to-consume are in high demand. This monitoring allows determining content toxic pathogenic contaminants confirms compliance objects being tested with established regulatory requirements. Mobile tests (so called test systems) provide opportunity wide range without involving specialized laboratories highly qualified specialists. Thus, systems for detection serve as useful addition to confirming instrumental analytical methods. An actively developing approach this field is using immunochromatographic strips, which strips all necessary reagents applied membrane components system. Contact strip sample tested, initiates further interactions generates recordable or visually assessable optical signal. The market based on analysis constantly growing, thus offering permanently widening choice solutions. However, recent years there has been a real boom new developments immunochromatography field, various options sensitive information capacitive systems. study systematizes these provides their comparative assessment terms prospects technological implementation practical application coming years. opportunities designing antibodies alternative receptor molecules controlling affinity selectivity recognition compounds monitored considered. advantages limitations nanodispersed markers non-optical methods registration discussed. quantitative via characterized. developed design multiplex control — simultaneous several presented. Examples integration automatic registration, processing, transfer, storage results numerous represented.

Language: Английский

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Dual-responsive ratiometric luminescent assay for visual recognition of tetracyclines based on in situ encapsulation of Eu(III) and carbon dots into metal-organic frameworks

Bulletin of the Chemical Society of Japan, Journal Year: 2025, Volume and Issue: 98(2)

Published: Feb. 1, 2025

Abstract An efficient method of in situ self-assembly was utilized to encapsulate Eu3+ and carbon dots (CDs) within ZIF-8, creating a Eu3+/CDs@ZIF-8 dual-emissive ratiometric luminescent assay specifically designed for the recognition tetracyclines (TCs). As concentration TCs rises, blue luminescence from CDs diminishes while red intensifies. This mechanism, balancing 2 emissions, allows high-sensitivity detection water milk. quench emission via inner filter effect coordinate with enhance emission, causing visible color shift. Consequently, can be visually observed shift red. Furthermore, developed test strip offers portable convenient solution detection, making it suitable on-site analysis. The dual-emission self-calibration platform introduces novel approach identification food samples, providing robust reliable monitoring ensuring environmental safety.

Language: Английский

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Smartphone-assisted sensing platform based on dual-responsive nitrogen-doped carbon dots for enzyme-free and visual quantitative detection of Cu2+ and glyphosate

Microchemical Journal, Journal Year: 2024, Volume and Issue: 207, P. 112166 - 112166

Published: Nov. 14, 2024

Language: Английский

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