The micro(nano)plastics perspective: exploring cancer development and therapy

Molecular Cancer, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 24, 2025

Microplastics, as an emerging environmental pollutant, have received widespread attention for their potential impact on ecosystems and human health. Microplastics are defined plastic particles less than 5 millimeters in diameter can be categorized primary secondary microplastics. Primary microplastics usually originate directly from industrial production, while formed by the degradation of larger items. capable triggering cytotoxicity chronic inflammation, may promote cancer through mechanisms such pro-inflammatory responses, oxidative stress endocrine disruption. In addition, improved bring new perspectives to therapy, studies drug carriers underway, showing high targeting bioavailability. Although current suggest association between certain cancers (e.g., lung, liver, breast cancers), long-term effects specific still need studied. This review aimed at exploring carcinogenicity promising applications therapy provides important directions future research emphasizes multidisciplinary collaboration address this global health challenge.

Language: Английский

---

Terrestrial characterization factors for bio- and fossil-based plastics: microplastics ingestion and additives release

Waste Management, Journal Year: 2025, Volume and Issue: 196, P. 106 - 114

Published: Feb. 25, 2025

Language: Английский

---

Photodegradation Controls of Potential Toxicity of Secondary Sunscreen-Derived Microplastics and Associated Leachates

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

The escalating environmental concern over secondary microplastics (SMPs) stems from their physicochemical evolution primary (PMPs), yet the contribution of varying transformations to ultimate risks remains unknown. In this study, a photomechanical degradation process was employed convert sunscreen-derived (SDMPs) into SDMPs. While mechanical caused physical fragmentation, photodegradation induced both and chemical alterations, introducing surface oxidation, bond scission, cross-linking Employing combination alkaline digestion pyrolysis GC-MS techniques, it observed that fragmentation photooxidation led heightened intracellular sequestration MPs. Although bioaccumulated SDMPs could be indicated by enlarged lysosomes fragmented mitochondria, toxicity at cellular level primarily driven post-photodegradation. A nontargeted analysis employing high-resolution mass spectrometry identified 46 plastic-associated compounds in leachate, with photodegradation-induced playing crucial role dissociation hydrophobic additives oxidative conversion leached compounds. leachate exacerbated photodegradation, mitochondrial serving as subcellular biomarker, indicative toxicity. This study elucidates pivotal augmenting cytotoxicity SDMPs, shedding light on intricate interplay between risks.

Language: Английский

---

Characteristics and spatial distribution of marine litter on the Moroccan Mediterranean coasts: Insights from Al Hoceima region in the central southern Alboran Sea

Marine Pollution Bulletin, Journal Year: 2025, Volume and Issue: 215, P. 117864 - 117864

Published: March 23, 2025

Language: Английский

---

Hormonal disruption from plastic ingestion in northern fulmars: activation and inhibition of estrogen receptors

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 126145 - 126145

Published: March 1, 2025

Language: Английский

---

Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications

AIMS environmental science, Journal Year: 2025, Volume and Issue: 12(2), P. 321 - 351

Published: Jan. 1, 2025

Language: Английский

---

A comprehensive review on exposure to toxins and health risks from plastic waste: Challenges, mitigation measures, and policy interventions

Waste Management Bulletin, Journal Year: 2025, Volume and Issue: unknown, P. 100204 - 100204

Published: April 1, 2025

Language: Английский

---

Polyvinyl chloride applications along with methods for managing its end-of-life items: A review

Progress in Rubber Plastics and Recycling Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

Owing to its unique blend of properties, polyvinyl chloride (PVC) has become one the most important polymers that have been used in everyday life for many years. Its short- and long-term applications span multiple key industries such as building, electrical/electronic insulation, packaging, healthcare. These produce high volumes PVC solid items require responsible management when they reach their end-of-life because are not biodegradable. Simple affordable methods diverting this waste from landfills would contribute positively towards combating environmental problems. However, approaches reported literature there is a need collate easier comparison. For example, some alternative highly effective transforming into range valuable products but still associated with secondary pollution. This overview covers different facets virgin (rigid, semi-rigid, flexible), focusing mainly on importance, global increase use, waste’s recyclability. In addition pros cons recycling strategies, influence specific factors expanding market also considered albeit briefly. Notably, [Formula: see text]50 % world’s annual production utilization capacity accounted by meant building applications; these drive growth market.

Language: Английский

---

Efficient magnetic adsorption of polystyrene nanoplastic from aqueous solutions by eco-friendly Fe3O4 nanoparticles: Removal, kinetic and isotherm modeling studies

Journal of Environmental Health Science and Engineering, Journal Year: 2024, Volume and Issue: 23(1)

Published: Dec. 23, 2024

Language: Английский

---