Journal of Biosciences and Medicines,
Journal Year:
2023,
Volume and Issue:
11(09), P. 90 - 113
Published: Jan. 1, 2023
Long
COVID
has
been
studied
as
different
sequelae
that
some
individuals
can
develop
after
the
acute
phase
of
disease.
Persistent
symptoms
such
dry
cough,
fatigue,
and
dyspnea
remain
six
months
COVID-19
cure.
Others
lung
fibrosis,
kidney
injury,
thrombotic
risk
also
are
observed.
Here,
a
deep
review
each
human
organ
system
infected
by
virus
was
performed
aiming
to
show
how
molecules
expression
cell
signaling
induce
organism
cure
or
injuries
and,
subsequently
sequelae.
The
suggests
importance
public
health
surveillance
for
these
cases
including
more
comprehensive
analysis
molecular
biology
tools
clarify
assist
in
prognosis,
treatment,
preventive
methods
potentially
serious
disorders
post-COVID-19
patients.
Frontiers in Veterinary Science,
Journal Year:
2023,
Volume and Issue:
10
Published: Feb. 2, 2023
Stress
and
general
anesthesia
have
an
impact
on
the
functional
response
of
organism
due
to
detrimental
effects
cardiovascular,
immunological,
metabolic
function,
which
could
limit
organism's
infectious
event.
Animal
studies
formed
essential
step
in
understanding
mitigating
diseases,
as
complexities
physiology
immunity
cannot
yet
be
replicated
vivo
.
Using
animals
research
continues
come
under
increasing
societal
scrutiny,
it
is
therefore
crucial
that
welfare
used
disease
optimized
meet
both
expectations
improve
scientific
outcomes.
Everyday
management
procedures
animal
are
known
cause
stress,
can
not
only
poorer
outcomes,
but
also
introduces
variables
studies.
Whilst
necessary
at
times
reduce
stress
enhance
research,
evidence
physiological
immunological
disruption
caused
by
increasing.
To
better
understand
quantify
study
utilizing
most
appropriate
monitoring
strategies
imperative.
This
article
aims
analyze
recent
about
uncontrolled
variables,
well
reviewing
technologies
models
during
diseases.
Viruses,
Journal Year:
2021,
Volume and Issue:
13(7), P. 1346 - 1346
Published: July 12, 2021
The
SARS-CoV-2
virus
causing
COVID-19
disease
has
emerged
expeditiously
in
the
world
and
been
declared
pandemic
since
March
2020,
by
World
Health
Organization
(WHO).
destructive
effects
of
infection
are
increased
among
patients
with
pre-existing
chronic
conditions
and,
particular,
this
review
focuses
on
underlying
cardiovascular
complications.
expression
pattern
potential
functions
binding
receptors
attributes
tropism
a
physio-pathological
state
heart
blood
vessel
precisely
described.
Of
note,
atheroprotective
role
ACE2
is
reviewed.
A
detailed
description
possible
detrimental
terms
vascular
leakage,
including
endothelial
glycocalyx
dysfunction
bradykinin
1
receptor
stimulation
concisely
stated.
Furthermore,
molecular
mechanisms
induced
clot
formation
association
host
defense
components,
activation
FXIIa,
complements
platelets,
dysfunction,
immune
cell
responses
cytokine-mediated
action
well
elaborated.
Moreover,
brief
clinical
update
patient
complications
those
who
had
new
onset
post-COVID-19
was
also
discussed.
Taken
together,
provides
an
overview
mechanistic
aspects
devastating
effects,
vital
organs
such
as
vessels.
International Journal of Molecular Medicine,
Journal Year:
2024,
Volume and Issue:
53(4)
Published: Feb. 22, 2024
Heart
disease
remains
a
global
health
challenge,
contributing
notably
to
morbidity
and
mortality.
The
lymphatic
vasculature,
an
integral
component
of
the
cardiovascular
system,
plays
crucial
role
in
regulating
essential
physiological
processes,
including
fluid
balance,
transportation
extravasated
proteins
immune
cell
trafficking,
all
which
are
important
for
heart
function.
Through
thorough
scientometric
analysis
extensive
research,
present
review
identified
lymphangiogenesis
as
hotspot
mechanisms
underlying
impaired
cardiac
inadequate
lymph
drainage
various
diseases
discussed.
Furthermore,
way
used
improve
effectively
regulate
variety
associated
signaling
pathways
was
investigated.
Notably,
current
also
highlights
impact
Traditional
Chinese
Medicine
(TCM)
on
lymphangiogenesis,
aiming
establish
clinical
basis
potential
TCM
by
promoting
lymphangiogenesis.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2022,
Volume and Issue:
unknown
Published: March 31, 2022
Abstract
The
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
is
known
to
present
with
pulmonary
and
extra-pulmonary
organ
complications.
In
comparison
the
2009
pandemic
(pH1N1),
SARS-CoV-2
infection
likely
lead
more
disease,
multi-organ
effects,
including
cardiovascular
disease.
has
been
associated
long-term
but
molecular
changes
govern
this
remain
unknown.
study,
we
investigated
landscape
of
cardiac
tissues
collected
at
rapid
autopsy
from
SARS-CoV-2,
pH1N1,
control
patients
using
targeted
spatial
transcriptomics
approaches.
Although
was
not
detected
in
tissue,
host
showed
upregulation
genes
DNA
damage
repair,
heat
shock,
M1-like
macrophage
infiltration
COVID-19
patients.
patient
samples,
were
further
confirmed
by
γ−H2Ax
immunohistochemistry.
comparison,
pH1N1
Interferon-stimulated
(ISGs),
particular
interferon
complement
pathways,
when
compared
These
data
demonstrate
emergence
distinct
transcriptomic
profiles
influenza
supporting
need
for
a
greater
understanding
effects
on
organs,
system
patients,
delineate
immunopathobiology
infection,
long
term
impact
health.
Cureus,
Journal Year:
2021,
Volume and Issue:
unknown
Published: Oct. 11, 2021
Severe
acute
respiratory
syndrome
coronavirus
(SARS-CoV-2)
emerged
from
Wuhan,
China,
in
2019,
causing
disease
19
(COVID-19)
and
creating
a
global
pandemic
affecting
millions
of
people
worldwide.
Though
COVID-19
primarily
affects
the
pulmonary
structures,
deleterious
effects
can
also
occur
cardiac
system.
We
present
case
patient
with
recurrent
pericardial
effusions
secondary
to
infection,
an
unusual
cardiovascular
manifestation
this
disease.
A
47-year-old
man
presented
altered
mental
status
tested
positive
for
COVID-19.
He
left
against
medical
advice
later
two
weeks
pleuritic
chest
pain
associated
shortness
breath.
His
symptoms
were
attributed
moderate-
large-sized
effusion,
without
evidence
tamponade,
as
confirmed
by
echocardiography.
The
fluid
was
removed
pericardiocentesis;
analysis
negative
malignant
cells,
inflammatory
markers,
or
microbiologic
studies.
Reaccumulation
necessitated
placement
window,
resulting
resolution
his
symptoms.
There
are
limited
reports
demonstrating
association
effusion
infection.
is
likely
response
leading
capillary
leakage,
traversing
serous
pericardium.
In
addition
other
demonstrated
effects,
appears
be
effusion.
Due
rise
cases,
it
essential
consider
rare
but
potential
complication
virus.
primary
clinical
manifestation,
nature,
potentially
result
tamponade
physiology.
Pensar en Movimiento Revista de Ciencias del Ejercicio y la Salud,
Journal Year:
2023,
Volume and Issue:
21(1), P. e53531 - e53531
Published: April 28, 2023
El
propósito
del
estudio
fue
cuantificar
el
tamaño
de
efecto
(TE)
ejercicio
aeróbico
sobre
la
capacidad
cardiorrespiratoria
en
sobrevivientes
enfermedad
COVID-19,
producida
por
virus
SARS-CoV
2.
Se
revisaron
dos
bases
datos
(EBSCO
host
y
PubMed)
entre
los
meses
agosto
a
noviembre
año
2021.
encontraron
142,656
posibles
artículos
luego
varios
filtros,
se
incluyeron
9
estudios
que
cumplían
requisitos
inclusión.
usó
modelo
efectos
aleatorios.
obtuvieron
12
TE
un
primer
metaanálisis
tuvo
sesgo
(según
prueba
Egger).
Tras
identificar
eliminar
grupos
con
extremo,
obtuvo
corregido
sin
7
TE,
donde
encontró
tiene
significativo,
positivo
magnitud
grande,
condición
COVID-19
(TE=0.849;
IC95%:
0.715
-
0.982;
Q=7.13;
p=0.522;
I2=0.87%;
Egger
p=0.205).
Las
intervenciones
favorecen
mejora
cardiorrespiratoria,
pacientes
COVID-19.
Dos
aplicaron
solo
aeróbico,
mientras
otros
siete,
combinaban
fuerza
otras
modalidades.
En
todos
casos
significativo.
Finalmente,
estos
resultados
fueron
relativamente
homogéneos,
evidenciar
influencia
variables
moderadoras.
Cureus,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Aug. 16, 2023
With
the
rapid
emergence
and
prevalence
of
SARS-CoV-2
worldwide,
cases
COVID-19-associated
nephropathy
(COVAN)
from
collapsing
focal
segmental
glomerulosclerosis
(cFSGS)
have
been
reported,
associations
between
two
are
actively
being
studied.
Creating
appropriate
treatment
guidelines
for
COVAN
requires
further
understanding
pathophysiology
this
type
kidney
injury.
This
case
report
outlines
a
77-year-old
patient
admitted
to
hospital
COVID-19
infection
with
subsequent
renal
biopsy
indicating
cFSGS,
adding
data
exploring
relationship
infections,
cFSGS
associated
risk
factors.
Current
on
similar
those
other
causes
but
continue
poor
outcomes
resistance
treatments.
Further
research
needs
be
done
both
clinical
assessment
provide
timely
life-saving
interventions.
