Genotoxic and neurotoxic potential of intracellular nanoplastics: A review

Journal of Applied Toxicology, Journal Year: 2024, Volume and Issue: 44(11), P. 1657 - 1678

Published: March 17, 2024

Abstract Plastic waste comprises polymers of different chemicals that disintegrate into nanoplastic particles (NPLs) 1–100‐nm size, thereby littering the environment and posing a threat to wildlife human health. Research on NPL contamination has up now focused ecotoxicology effects pollution rather than health risks. This review aimed speculate about possible properties carcinogenic neurotoxic as pollutants. Given their low‐dimensional size high surface ratio, NPLs can easily penetrate biological membranes cause functional structural damage in cells. Once inside cell, interrupt autophagy flux cellular debris, alter proteostasis, provoke mitochondrial dysfunctions, induce endoplasmic reticulum stress. Harmful metabolic processes induced by include oxidative stress (OS), ROS generation, pro‐inflammatory reactions. Depending cell cycle status, may direct DNA damage, tumorigenesis, lately carcinogenesis tissues with self‐renewal capabilities like epithelia. In cells able live longest neurons, could trigger neurodegeneration promoting toxic proteinaceous aggregates, OS, chronic inflammation. genotoxicity neurotoxicity are discussed based gathered evidence, when available, within context intracellular uptake these newcomer nanoparticles. summary, this explains how risk evaluation for benefit from accurately monitoring toxicokinetics toxicodynamics at resolution level.

Language: Английский

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Feasibility of waste-to-hydrogen generation system based on gasification/pyrolysis: a comprehensive review of experimental studies

Journal of Thermal Analysis and Calorimetry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 19, 2024

Language: Английский

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Pollution characterization and multi-index ecological risk assessment of microplastics in urban rivers from a Chinese megacity

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136145 - 136145

Published: Oct. 11, 2024

Language: Английский

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Microbiological Characterization of the Biofilms Colonizing Bioplastics in Natural Marine Conditions: A Comparison between PHBV and PLA

Microorganisms, Journal Year: 2023, Volume and Issue: 11(6), P. 1461 - 1461

Published: May 31, 2023

Biodegradable polymers offer a potential solution to marine pollution caused by plastic waste. The biofilms that formed on the surfaces of poly(lactide acid) (PLA) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) were studied. Bioplastics exposed for 6 months conditions in Mediterranean Sea, their assessed. presence specific PLA PHBV degraders was also showed extensive areas with microbial accumulations this led higher surface densities than (4.75 vs. 5.16 log CFU/cm2). Both polymers' wide variety structures, including bacteria, fungi, unicellular algae choanoflagellates. A high bacterial diversity observed, differences between two polymers, particularly at phylum level, over 70% bacteria affiliated three phyla. Differences metagenome functions detected, revealing proteins involved biodegradation biofilms. Four isolates belonging Proteobacteria class identified as degraders, demonstrating species polymer seawater. No confirming its low biodegradability environments. This pilot study establish baseline further studies aimed comprehending biopolymers.

Language: Английский

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Assessing the Plastisphere from Floating Plastics in the Northwestern Mediterranean Sea, with Emphasis on Viruses

Microorganisms, Journal Year: 2024, Volume and Issue: 12(3), P. 444 - 444

Published: Feb. 22, 2024

Plastics in the ocean create "plastisphere", a diverse habitat hosting various life forms. Other than pollution induced by plastics, co-occurrence of primary producers, symbiotic organisms, decomposers, and pathogens within plastisphere raises questions about how they influence dynamics marine ecosystems. Here, we used shotgun DNA-sequencing approach to describe species thriving on floating plastics collected two Mediterranean sites. Our findings revealed many bacteria, eukaryotes, viruses, archaea each plastic. Proteobacteria was dominant (70% reads entire dataset), with other groups such as Ascomycota fungi (11%) Bacteroidetes (9%) also being represented. The community structure not affected polymeric composition or plastic shape. Notably, pathogenic Vibrio species, including V. campbelli, alginolyticus, coralliilyticus, were among most abundant species. Viruses, despite showing lower relative abundances, occurred all samples, especially Herpesvirales, Caudovirales, Poxviridae groups. A significant finding presence White Spot Syndrome virus (WSSV). This pathogen, responsible for devastating outbreaks aquaculture systems, had been previously reported plastisphere. study emphasizes need further investigation into ecological economic impacts organisms ocean.

Language: Английский

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Culturing the Plastisphere: comparing methods to isolate culturable bacteria colonising microplastics

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Oct. 3, 2023

Microplastics quickly become colonised by diverse microbial communities, known as the Plastisphere. There is growing concern that microplastics may support enrichment and spread of pathogenic or antimicrobial resistant microorganisms, although research to unique role in comparison control particles remains inconclusive. Limitations this include microbiological methods available for isolating adhered microbes. Culture-based provide some most established, accessible cost-effective protocols, which could be extremely useful helping address remaining key questions Plastisphere research. Previous works have successfully cultured bacteria from plastics, but these not yet been reviewed, nor compared efficiency. In study, we four common biofilm extraction (swabbing, sonication, vortexing, sonication followed vortexing) extract culture a mixed community both microplastic (polyethylene, polypropylene polystyrene) (wood glass) particles. Biofilm efficiency viability bacterial suspension was determined comparing CFU/mL different groups bacteria. This verified against optical density 16S rRNA qPCR. Overall, found all tested were able remove biofilms, varying efficiencies. Sonicating with glass beads 15 min, vortexing further minute, generated highest yield therefore greatest removal culturable, biofilm-forming

Language: Английский

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Microplastic biodegradability dependent responses of plastisphere antibiotic resistance to simulated freshwater-seawater shift in onshore marine aquaculture zones

Environmental Pollution, Journal Year: 2023, Volume and Issue: 331, P. 121828 - 121828

Published: May 15, 2023

Language: Английский

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Interactions between nanoplastics and Tetrahymena thermophila: Low toxicity vs. potential biodegradation

Chemosphere, Journal Year: 2025, Volume and Issue: 373, P. 144166 - 144166

Published: Feb. 5, 2025

Language: Английский

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Nanoplastics in Wastewater: Monitoring, Ecotoxicity, and Remediation

Published: Jan. 1, 2025

Language: Английский

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Integrated Multimethod Approach for Size-Specific Assessment of Potentially Toxic Element Adsorption onto Micro‐ and Nanoplastics: Implications for Environmental Risk

Nanoscale, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

AF4-MALS-ICP-MS enables size-resolved characterisation of potentially toxic elements (PTEs) adsorption onto COOH-functionalised polystyrene nanoplastics (COOH-PSNPs), revealing the distribution PTEs across distinct size fractions.

Language: Английский

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