Oropouche Virus (OROV) in Pregnancy: An Emerging Cause of Placental and Fetal Infection Associated with Stillbirth and Microcephaly following Vertical Transmission

Viruses, Journal Year: 2024, Volume and Issue: 16(9), P. 1435 - 1435

Published: Sept. 9, 2024

Oropouche virus (OROV) is an emerging arbovirus endemic in Latin America and the Caribbean that causes fever, a febrile illness clinically resembles some other arboviral infections. It currently spreading through Brazil surrounding countries, where, from 1 January to August 2024, more than 8000 cases have been identified Bolivia, Brazil, Columbia, Peru for first time Cuba. Travelers with fever United States Europe. A significant occurrence during this epidemic has report of pregnant women infected OROV who had miscarriages stillborn fetuses placental, umbilical blood fetal somatic organ samples were RT-PCR positive negative arboviruses. In addition, there four newborn infants having microcephaly, which cerebrospinal fluid tested IgM antibodies This communication examines biology, epidemiology, clinical features OROV, summarizes 2023–2024 epidemic, describes reported vertical transmission congenital infection, death, microcephaly addresses experimental animal infections potential placental pathology findings reviews bunyavirus agents can cause transmission. Recommendations are made travelling regions affected by epidemic.

Language: Английский

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Risk of neonatal SARS-CoV-2 infection: a retrospective cohort study based on infected mothers with gestational diabetes mellitus

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 30, 2025

Background The COVID-19 pandemic has posed unprecedented challenges to global public health, especially for pregnant women and their offspring. However, little is known about the impact of maternal SARS-CoV-2 infection on neonatal outcomes, particularly in context coexisting gestational diabetes mellitus (GDM). Methods Hospitalized with were retrospectively enrolled between November 2022 January 2023, matched subjects free based propensity scores. All tested upon admission as part routine procedures, then divided into groups GDM (SARS2+GDM), but without (SARS2+noGDM), or (Normal group). A logistic regression model was used study risk GDM, perinatal infection, interaction infection. Results Of 378 rate higher group compared only group, both rates lower than that normal control group. Logistic analysis identified an where (odds ratio [OR] = 0.31, 95%CI: 0.22-0.44) vaccination anti-SARS-CoV-2 (OR 0.70, 0.50-0.98) associated odds while pre-pregnancy body mass index (BMI) 1.06, 95% CI: 1.02-1.10) 1.97, 1.21-3.21) Conclusions We demonstrate coexistence increased probability

Language: Английский

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Controversies in chronic histiocytic intervillositis

Journal of Gynecology Obstetrics and Human Reproduction, Journal Year: 2025, Volume and Issue: unknown, P. 102931 - 102931

Published: Feb. 1, 2025

Language: Английский

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Clinical Manifestations and Outcomes of SARS-CoV-2 Infection in Children and Adolescents

Infectious Disease Clinics of North America, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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