Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 251 - 285
Published: Nov. 15, 2024
The
encapsulation
of
active
pharmaceutical
ingredients
(APIs)
in
microbeads
is
an
essential
step
drug
delivery;
however,
it
also
inherently
associated
with
the
need
to
control
particle
size
and
release
profiles.
Nevertheless,
most
conventional
methods
microencapsulation
fail
provide
consistent
results.
A
new
method
called
vibration-assisted
microbead
coating
a
novel
unified
technique
utilizing
mechanical
vibrations
enable
controlled,
uniform
on
APIs.
This
chapter
discusses
technology
performed
by
authors
through
formation
physical
activity
focuses
achieving
final
coated
surface
API,
shape,
size,
loading
vibration
parameters.
Additionally,
this
biocompatibility
stability
surface.
means
has
high
potential
for
delivery.
reduces
traditional
challenges
encapsulation,
if
not
eliminates
them,
more
reliable.
Based
abovementioned
findings,
propose
following
main
areas
their
further
work:
optimisation
parameters
various
APIs,
research
into
long-term
loading–release
profile,
possible
use
targeted
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(13)
Published: April 1, 2025
Abstract
The
growing
presence
of
pharmaceutical
pollutants
in
aquatic
environments
poses
significant
threats
to
both
human
health
and
ecosystems.
Despite
their
crucial
role
healthcare,
pharmaceuticals
enter
water
systems
through
various
sources,
making
them
some
the
most
critical
environmental
contaminants.
Traditional
wastewater
treatments,
which
are
classified
into
physical,
chemical,
biological
techniques,
often
struggle
effectively
remove
pharmaceuticals.
Among
these
methods,
adsorption
stands
out
as
a
reliable
versatile
approach
for
removing
organic
enhancing
efficiency
treatment
processes.
Biopolymers,
particularly
chitosan,
gaining
attention
due
numerous
advantages,
including
biocompatibility,
biodegradability,
affordability,
high
capability,
non‐toxicity,
availability
from
diverse
natural
sources.
Chitosan,
hydrophilic
biopolymer,
can
be
chemically
modified
by
incorporating
nanoparticles
(e.g.,
metal
oxides,
carbon‐based
materials,
magnetic
particles)
boost
its
efficiency.
These
advancements
enable
chitosan‐based
nanocomposites
range
pharmaceuticals,
antibiotics,
analgesics,
hormones,
water.
This
review
examines
latest
developments
nanocomposite
adsorbents,
emphasizing
fundamental
mechanisms,
optimization
conditions,
kinetic
behaviors,
isotherm
models.
factors
collectively
determine
capturing
pollutants.
Moreover,
underscores
potential
materials
remediation,
offering
valuable
insights
application
future
research
directions.
Ultimately,
aim
this
is
provide
insight
offer
an
innovative
effective
solution
challenge
contamination
By
addressing
key
challenges
utilizing
advanced
material
designs,
adsorbents
hold
great
promise
sustainable
efficient
removal
systems.
