Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 251 - 285
Published: Nov. 15, 2024
The
encapsulation
of
active
pharmaceutical
ingredients
(APIs)
in
microbeads
is
an
essential
step
drug
delivery;
however,
it
also
inherently
associated
with
the
need
to
control
particle
size
and
release
profiles.
Nevertheless,
most
conventional
methods
microencapsulation
fail
provide
consistent
results.
A
new
method
called
vibration-assisted
microbead
coating
a
novel
unified
technique
utilizing
mechanical
vibrations
enable
controlled,
uniform
on
APIs.
This
chapter
discusses
technology
performed
by
authors
through
formation
physical
activity
focuses
achieving
final
coated
surface
API,
shape,
size,
loading
vibration
parameters.
Additionally,
this
biocompatibility
stability
surface.
means
has
high
potential
for
delivery.
reduces
traditional
challenges
encapsulation,
if
not
eliminates
them,
more
reliable.
Based
abovementioned
findings,
propose
following
main
areas
their
further
work:
optimisation
parameters
various
APIs,
research
into
long-term
loading–release
profile,
possible
use
targeted
To
address
the
challenges
of
high
energy
consumption
and
low
efficiency
issues
in
recovery
phenols
oils
from
coal
chemical
wastewater
(CCW),
a
MOFs/SCP
adsorbent
with
large
adsorption
capacity
easy
desorption
was
designed
synthesized
this
study.
Based
on
this,
construction
new
full-process
treatment
mode,
known
as
"Adsorption-Desorption-Regeneration-Recovery"
(ADRR),
which
is
aimed
to
efficiently
recover
CCW.
The
results
showed
that
ADRR
mode
exhibited
persistent
stability,
adsorption-desorption
consistently
surpassing
95
%.
Meanwhile,
regeneration
methanol
achieved
around
90
%
83
respectively.
analysis
behavior
model
indicated
by
predominantly
comprised
monolayer
characterized
spontaneity,
heat
absorption,
disorder.
dynamic
shows
strong
correlation
predicting
assessing
capacity,
rate,
equilibrium,
operating
parameters.
Finally,
set
structural
analyses
paired
molecular
dynamics
simulations
illustrated
micro-interaction
mechanisms
between
depend
their
distinctive
hydrophobic
nature
porous
capabilities.
This
interaction
primarily
propelled
electrostatic
interactions,
π-π
hydrogen
bonding.
study's
findings
hold
significant
practical
importance
for
achieving
high-value
CCW,
promoting
clean
sustainable
growth
industry.
Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 251 - 285
Published: Nov. 15, 2024
The
encapsulation
of
active
pharmaceutical
ingredients
(APIs)
in
microbeads
is
an
essential
step
drug
delivery;
however,
it
also
inherently
associated
with
the
need
to
control
particle
size
and
release
profiles.
Nevertheless,
most
conventional
methods
microencapsulation
fail
provide
consistent
results.
A
new
method
called
vibration-assisted
microbead
coating
a
novel
unified
technique
utilizing
mechanical
vibrations
enable
controlled,
uniform
on
APIs.
This
chapter
discusses
technology
performed
by
authors
through
formation
physical
activity
focuses
achieving
final
coated
surface
API,
shape,
size,
loading
vibration
parameters.
Additionally,
this
biocompatibility
stability
surface.
means
has
high
potential
for
delivery.
reduces
traditional
challenges
encapsulation,
if
not
eliminates
them,
more
reliable.
Based
abovementioned
findings,
propose
following
main
areas
their
further
work:
optimisation
parameters
various
APIs,
research
into
long-term
loading–release
profile,
possible
use
targeted
