New Strategies for the Extraction of Antioxidants from Fruits and Their By-Products: A Systematic Review

Plants, Journal Year: 2025, Volume and Issue: 14(5), P. 755 - 755

Published: March 1, 2025

This review highlights the recent advancements in extraction techniques for bioactive compounds from natural sources, focusing on methodologies that enhance both efficiency and sustainability. Techniques such as pressurized hot water (PHWE), solid-state fermentation (SSF), ionic liquids (ILs), electrohydrodynamic (EHD) methods have shown significant potential improving yields while preserving bioactivity of target compounds. These innovative approaches offer advantages over traditional methods, including reduced energy consumption, minimal environmental impact, ability to extract thermosensitive PHWE EHD are particularly effective extracting antioxidants compounds, whereas SSF provides an environmentally friendly alternative by valorizing agro-industrial waste. Ionic liquids, although promising complex phytochemicals, face challenges related scalability economic feasibility. The adoption these advanced represents a shift toward more sustainable cost-effective processes, promoting discovery utilization high-value also contribute development eco-friendly, strategies align with green chemistry principles regulatory standards. However, further research technological required address existing limitations ensure widespread application industrial pharmaceutical sectors.

Language: Английский

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High-Pressure Extraction Techniques for Efficient Recovery of Flavonoids and Coumarins from Flower Seeds

Processes, Journal Year: 2025, Volume and Issue: 13(2), P. 300 - 300

Published: Jan. 22, 2025

The extraction of bioactive compounds, such as flavonoids and coumarins, from natural sources has gained significant attention due to their potential health benefits. This review aims explore the application high-pressure processes, particularly supercritical fluid (SFE) pressurized liquid (PLE), for obtaining coumarins flower seeds. These techniques offer a greener, more efficient alternative conventional methods, minimizing use harmful solvents improving yield purity target compounds. Flower seeds, rich source molecules, are an underutilized reservoir these valuable For example, seeds plants Calendula officinalis (calendula) Helianthus annuus (sunflower) in coumarins. proposed will examine influence parameters—such temperature, pressure, solvent choice, time—on quality provide comprehensive understanding methods optimize protocols efficient, sustainable

Language: Английский

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Optimization of Ultrasonic-Enzyme Synergistic Extraction of Proanthocyanidins from Jujube: Purification, Characterization, and Bioactivity Study

Molecules, Journal Year: 2025, Volume and Issue: 30(3), P. 619 - 619

Published: Jan. 31, 2025

Proanthocyanidins have received extensive attention due to their high functional value, but sources are limited. Therefore, this experiment studied the preparation, biological activities, and characterization of proanthocyanidins from Chinese jujube (Ziziphus jujuba Mill. cv. Muzao) at different periods, aiming explore a new source enhance utilization value. Through ultrasonic-assisted enzymatic extraction, optimal extraction conditions for PC Muzao were determined, yielding proanthocyanidin content 2.01%. Purification using AB-8 macroporous resin increased by 11 times. The bioactivity results indicated that demonstrated significant in vitro antioxidant activity (scavenging rate ≥ 83.4%) blood glucose-lowering (inhibition 84.7%). Both activities decreased with maturity, while degree polymerization also exhibited positive effect. Mass spectrometry identified total 102 compounds, cyanidin-based compounds being most abundant, comprising 28 species. comprehensive research indicate oligomeric extracted, purified, isolated during young fruit stage exhibit diverse abundant content. They can be utilized purification proanthocyanidins, offering reference expansion natural development foods.

Language: Английский

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Optimization of Quercetin Extraction from Schisandra Chinensis by an Ultrasound‐Assisted Ionic Liquid‐Enzyme Composite System and Its Antioxidant Research Analysis

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(16)

Published: April 1, 2025

Abstract In this study, the effects of enzyme addition, ionic liquid concentration, and sonication time on yield quercetin in Schisandra chinensis ( S. ) were investigated by one‐way experiments their interactions with concentration as independent variables. The results showed that when addition was 16.413%, 1‐butyl‐3‐methylimidazolium chloride salt 0.390 mol/L, ultrasonication 43.770 min, 0.539 mg/g, which 8.694 times higher than traditional reflux extraction method. By network pharmacological analysis, 1867 antioxidant targets screened out.GO KEGG enrichment analyses indicated function might be related to chemical carcinogenesis‐reactive oxygen species pathway, PI3K‐Akt signalling pathway. activity also determining scavenging ability DPPH hydroxyl radicals. rates both 94.510% 64.922% quality 0.06 0.4 mg/mL, respectively, basically remained unchanged increase concentration.

Language: Английский

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Green extraction of bioactives from Vitis vinifera L. cv. Tannat pomace and chemical characterization by comprehensive two-dimensional liquid chromatography (LC × LC)

Journal of Chromatography A, Journal Year: 2025, Volume and Issue: 1754, P. 466030 - 466030

Published: May 8, 2025

Grape pomace is an important by-product generated during winemaking that still possesses relevant concentrations of interesting bioactive compounds. As the production this very high, developing strategies to produce its valorization in effort provide means for generation high-added value products desired. Tannat grapes are particularly rich phenolic compounds and, consequently, derived from them may be those components. The use compressed fluids-based extraction techniques, such as supercritical fluid (SFE) and pressurized liquids (PLE) retains good potential isolation natural matrices. In work, PLE explored obtain extracts grape presenting high antioxidant anticholinergic activities. After optimization, best conditions implied 55 % ethanol a solvent at 141 °C 20 min. Moreover, correlate observed bioactivities with particular chemical composition extracts, new two-dimensional comprehensive liquid chromatography (LC × LC) method coupled mass spectrometry (MS) was developed separate identify components present extract. LC analysis optimum extract separated >70 different analytes. Among them, proanthocyanidins were most abundant compounds, although others flavonols anthocyanins could also identified. Overall, obtained results demonstrate strong valorized, retaining excellent possibilities application fields.

Language: Английский

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Design of experiment for a sustainable extraction of phenolic compounds from pomegranate peels and proof of antioxidant and antimicrobial properties

Sustainable Chemistry and Pharmacy, Journal Year: 2024, Volume and Issue: 42, P. 101860 - 101860

Published: Nov. 28, 2024

Language: Английский

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