Dynamic Impacts of Sleep Disruption on Ecologically Assessed Affective, Behavioral, and Cognitive Risk Factors for Suicide: A Study Protocol

SLEEP Advances, Journal Year: 2025, Volume and Issue: 6(2)

Published: Feb. 12, 2025

Abstract Diminished sleep health is a known warning sign for suicide. However, the contexts and time periods within which diminished elevates suicide risk are unknown. Modeling complex process by impacts daily functioning establishing proximal factors can aid in addressing these important knowledge gaps. This paper describes methods research protocol study that aims to elucidate nature of sleep–suicide relationship develop an integrated model risk. Participants will be 200 adults at high recruited from psychiatric inpatient unit. They complete baseline assessment including clinical interviews self-reports, laboratory tasks with concurrent electroencephalography phenotype-relevant processes. followed 4 weeks ecological momentary digital phenotyping, coupled assessments via wearable used generate minute-by-minute metric cognitive effectiveness using Sleep Activity, Fatigue, Task Effectiveness algorithm index. Follow-up conducted 1-, 3-, 6-months post-hospital discharge determine how developed prospectively predicts suicidal ideation behavior. The results this have potential greatly enhance understanding why related real-world fluctuations risk, inform efforts better prevent, intervene reduce suicides.

Language: Английский

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Wearable Artificial Intelligence for Sleep Disorders: Scoping Review

Journal of Medical Internet Research, Journal Year: 2025, Volume and Issue: 27, P. e65272 - e65272

Published: May 6, 2025

Background Worldwide, 30%-45% of adults have sleep disorders, which are linked to major health issues such as diabetes and cardiovascular disease. Long-term monitoring with traditional in-lab testing is impractical due high costs. Wearable artificial intelligence (AI)–powered solutions offer accessible, scalable, continuous monitoring, improving the identification treatment problems. Objective This scoping review aims provide an overview AI-powered wearable devices used for focusing on study characteristics, technology features, AI methodologies detection analysis. Methods Seven electronic databases (MEDLINE, PsycINFO, Embase, IEEE Xplore, ACM Digital Library, Google Scholar, Scopus) were searched peer-reviewed literature published before March 2024. Keywords selected based 3 domains: AI, devices. The primary selection criterion was inclusion studies that utilized algorithms detect or predict various disorders using data from Study conducted in 2 steps: first, by reviewing titles abstracts, followed full-text screening. Two reviewers independently extraction, resolving discrepancies consensus. extracted synthesized a narrative approach. Results initial search yielded 615 articles, 46 met eligibility criteria included final majority focused apnea. widely deployed diagnosing screening disorders; however, none it treatment. Commercial most commonly type technology, appearing 30 out (65%) studies. Among these, brands rather than single large, well-known brand; 19 (41%) wrist-worn Respiratory 25 (54%) model development, heart rate (22/46, 48%) body movement (17/46, 37%). popular algorithm convolutional neural network, adopted 17 (37%) studies, random forest (14/46, 30%) support vector machines (12/46, 26%). Conclusions offers promising disorders. These can be diagnosis; research other apnea remains limited. To statistically synthesize performance efficacy results, more reviews needed. Technology companies should prioritize advancements deep learning invest treating given its potential. Further necessary validate machine techniques clinical develop useful analytics collection, prediction, classification, recommendation context

Language: Английский

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Sleep Disturbances and Suicidality in Posttraumatic Stress Disorder: An Overview of the Literature

Frontiers in Psychiatry, Journal Year: 2020, Volume and Issue: 11

Published: March 10, 2020

A causal relationship between sleep disturbances and suicidal behavior has been previously reported. Insomnia nightmares are considered as hallmarks of posttraumatic stress disorder (PTSD). In addition, patients with PTSD have an increased risk for suicidality. The present article gives overview about the existing literature on suicidality in context PTSD. It aims to demonstrate that diagnosing treating problems still underestimated target symptoms may provide preventive strategies respect However, heterogeneous study designs, different samples diverse outcome parameters hinder a direct comparison studies cannot be shown. More research is necessary clarify this complex tackle value treatment suicide prevention

Language: Английский

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Hypnotic medication use among inpatients with schizophrenia and major depressive disorder: results of a nationwide study

Sleep Medicine, Journal Year: 2021, Volume and Issue: 89, P. 23 - 30

Published: Nov. 22, 2021

Language: Английский

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Association between hospital-diagnosed sleep disorders and suicide: a nationwide cohort study

SLEEP, Journal Year: 2022, Volume and Issue: 45(5)

Published: March 18, 2022

Sleep disorders are related to mental disorders. Yet few studies have examined their association with suicide. We whether males and females diagnosed sleep had higher rates of suicide than individuals not In a cohort study, nationwide data on all aged 15+ years living in Denmark during 1980-2016 were analysed. identified through diagnoses recorded contacts somatic hospitals. Incidence Rate Ratios (IRR) estimated using Poisson regression models adjusted for covariates. all, 3,674,563 3,688,164 included, whom 82,223 (2.2%, mean age: 50.2, SD: 17.5) 40,003 (1.1%, 50.6, 19.9) disorder diagnoses. Compared those no disorders, the IRRs 1.6 (95% CI, 1.4-1.7) 2.2 1.8-2.6) respectively. Excess narcolepsy found (IRR:1.2, 95% 1.0-1.5) (IRR:3.3, 3.0-4.1), apnea (IRR:1.8, 1.5-2.2). A difference respect age sex was observed (P<0.001) between females. Males 4.1 3.1-5.5) 7.0 4.8-10.1), first 6 months after being disorder. associated even adjusting pre-existing Our findings suggest attention towards suicidality patients is warranted.

Language: Английский

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Functional changes in sleep-related arousal after ketamine administration in individuals with treatment-resistant depression

Translational Psychiatry, Journal Year: 2024, Volume and Issue: 14(1)

Published: June 4, 2024

Abstract The glutamatergic modulator ketamine is associated with changes in sleep, depression, and suicidal ideation (SI). This study sought to evaluate differences arousal-related sleep metrics between 36 individuals treatment-resistant major depression (TRD) 25 healthy volunteers (HVs). It also determine whether normalizes arousal TRD ketamine’s effects on mediate its antidepressant anti-SI effects. was a secondary analysis of biomarker-focused, randomized, double-blind, crossover trial (0.5 mg/kg) compared saline placebo. Polysomnography (PSG) studies were conducted one day before after ketamine/placebo infusions. Sleep measured using spectral power functions over time including alpha (quiet wakefulness), beta (alert delta (deep sleep) power, as well macroarchitecture variables, wakefulness onset (WASO), total (TST), rapid eye movement (REM) latency, Post-Sleep Onset Efficiency (PSOSE). At baseline, diagnostic included lower TST ( p = 0.006) shorter REM latency 0.04) the versus HV group. Ketamine’s temporal dynamic (relative placebo) increased earlier night later night. However, there no significant patterns alpha, beta, or metrics, mediation variables These results highlight role sleep-related part systemic neurobiological initiated administration. Clinical Trials Identifier: NCT00088699.

Language: Английский

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Analysis of Smartphone Triaxial Accelerometry for Monitoring Sleep-Disordered Breathing and Sleep Position at Home

IEEE Access, Journal Year: 2020, Volume and Issue: 8, P. 71231 - 71244

Published: Jan. 1, 2020

Obstructive sleep apnea (OSA) is a disorder in which repetitive upper airway obstructive events occur during sleep. These can induce hypoxia, risk factor for multiple cardiovascular and cerebrovascular diseases. OSA also known to be position-dependent some patients, referred as positional (pOSA). Screening pOSA necessary order design more personalized effective treatment strategies. In this article, we propose analyzing accelerometry signals, recorded with smartphone, detect monitor at home. Our objectives were to: (1) develop an algorithm detecting thoracic movement associated disordered breathing events; (2) compare the performance of smartphones monitoring tools type 3 portable monitor; (3) explore feasibility using smartphone retrieve reliable patient position data assess pOSA. Accelerometry signals collected through simultaneous overnight acquisition both devices 13 subjects. The tool showed high degree concordance compared device succeeded estimating apnea-hypopnea index (AHI) classifying severity level most To agreement between two systems, event-by-event comparison was performed, found sensitivity 90% positive predictive value 80%. It possible identify by determining ratio occurring specific versus time spent that night. novel results suggest are promising mHealth

Language: Английский

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The association between chronotype and suicidality among students of the medicine and psychology faculties – the mediating role of general mental health indices

Chronobiology International, Journal Year: 2021, Volume and Issue: 38(4), P. 509 - 517

Published: Jan. 4, 2021

The aim of the present study was to evaluate whether anxiety and insomnia symptoms, somatic social dysfunction mediate link between chronotype suicidality, as depressive symptoms are known do, among students faculties Medicine Psychology. Data from a total 289 were eligible for analysis. completed Suicide Behaviors Questionnaire – Revised, Composite Scale Morningness, General Health Questionnaire. Single-predictor linear regression models created predict with subsequent mediation A preference toward eveningness associated an increase in suicidality Somatic anxiety/insomnia, fully mediated relationship suicidality. Depressive found strongest effect size mediation. Social both but did not play mediating role. There might be need nonpsychotic mental health indices other than when assessing

Language: Английский

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Treatment of insomnia based on the mechanism of pathophysiology by acupuncture combined with herbal medicine: A review

Medicine, Journal Year: 2023, Volume and Issue: 102(11), P. e33213 - e33213

Published: March 17, 2023

Insomnia is a sleep disorder which severely affects patients mood, quality of life and social functioning, serves as trigger or risk factor to variety diseases such depression, cardiovascular cerebrovascular diseases, obesity diabetes, even increases the suicide, has become an increasingly widespread concern worldwide. Considerable research on insomnia been conducted in modern medicine recent years encouraging results have achieved fields genetics neurobiology. Unfortunately, however, pathogenesis remains elusive medicine, pharmacological treatment regarded conventional. However, course treatment, itself being questioned due potential dependence drug resistance now replaced by cognitive behavior therapy first-line treatment. As important component complementary alternative traditional Chinese especially non-pharmacological methods acupuncture, gaining increasing attention In this article, we discuss combination treat based neurobiology context medicine.

Language: Английский

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Effects of sleep quality on suicide risk in COVID-19 patients: The chain mediating of anxiety and depressive symptoms

Heliyon, Journal Year: 2023, Volume and Issue: 9(4), P. e15051 - e15051

Published: March 30, 2023

Although current studies have identified sleep disorders as an independent risk factor for suicide, the relationship between and suicide has not been well established. This study explored whether anxiety depressive symptoms are used mediators to participate in impact of quality on risk.This is a cross-sectional study. We administered psychological questionnaire participants, using combination self-assessment psychiatrist assessment.Sleep quality, risk, level were assessed by PSQI, NGASR, SAS SDS.The subjects 391 hospitalized COVID-19 patients from Wuhan hospitals. model 6 PROCESS (version 3.5) plug-in SPSS software conduct mediation test with variable, dependent intermediate variables.The severity disorder group (63.15 ± 13.71, 59.85 13.38, 6.52 3.67) higher than those non-sleep (49.83 13.14, 44.87 10.19, 2.87 3.26) (P < 0.001). The works well, total indirect effect was 0.22 (95%CI = [0.17, 0.28]), direct 0.16 [0.08, 0.24]).This scale.Anxiety played chain mediating role risk.

Language: Английский

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