Serum 25(OH)D levels and obstructive sleep apnea syndrome severity in patients without comorbidities: a systematic review and meta-analysis DOI Creative Commons
Marco Serafin,

Martina Vaninetti,

Ismahan Mohamed

et al.

Sleep And Breathing, Journal Year: 2024, Volume and Issue: 29(1)

Published: Dec. 9, 2024

The aim of the present systematic review was to corroborate existing evidence on how serum25(OH)D levels affect obstructive sleep apnea syndrome (OSAS) severity in absence comorbidities. From inception May 2024, PubMed, Scopus, and Embase electronic databases were systematically screened identify randomized controlled trials (RCTs), quasi-RCTs, prospective, retrospective studies. A strict search protocol applied following application PROSPERO, under registration number CRD42023468744. formulated question based PICO process was: "how do OSAS or result enhanced function?". Collected results finally reviewed for meta-analysis quality assessment according ROBINS-I tool. Data from 24 studies pooled divided into 15 case-control 9 cross-sectional All involved a total 2640 subjects 933 healthy subjects. underwent qualitative analysis whereas only 20 collected meta-analysis. Mild showed 25(OH)D non-statistically significant (P = 0.12) than patients moderate 0.004) severe < 0.001) differed significantly control groups. Meta-regression suggested that correlated inversely deficiency serum levels. Qualitative Egger's test revealed an elevated risk bias but low presence publication bias, respectively. Serum observed be proportional without coexisting morbidities. mild not different non-OSAS patients, suggesting vitamin supplementation improve potential disorders.

Language: Английский

The Associations of Vitamin D Status and Lifestyle Behaviors with General Obesity and Metabolically Unhealthy Obesity in Chinese Children and Adolescents DOI Open Access

Fangqu Liu,

Li Yan,

Chanhua Liang

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(4), P. 666 - 666

Published: Feb. 13, 2025

Vitamin D and lifestyle behaviors are closely related to children's health. However, current research on the combined influences of vitamin adherence 24-Hour Movement Guidelines (24-HMG) childhood obesity remains scarce. Our study aimed examine individual joint associations status number recommendations for adhering 24-HMG with among Chinese children adolescents. In this cross-sectional study, a total 4625 participants from Shenzhen, China, were recruited. was classified into two categories: adequacy inadequacy. The obtained validated questionnaire, including moderate-to-vigorous physical activity, screen time, sleep duration. General metabolically unhealthy (MUO) outcomes study. logistic regression model performed between status, guidelines met, obesity. inadequacy associated increased odds general MUO, adjusted ratios (95% CIs) 1.551 (1.080-2.226) 2.205 (1.319-3.686). Meeting 2-3 decreased obesity, 0.777 (0.626-0.965). Compared adequacy/meeting group, inadequacy/meeting 0-1 guideline group positively (adjusted odd ratio, 1.826 [95% CI: 1.167-2.857]) MUO (2.160, 1.175-3.972). addition, population-attributable fractions or/and meeting 28.4% 2.5-54.4%) 42.3% 11.5-73.1%) MUO. findings displayed that linked high respectively. Understanding these relationships could provide theoretical basis effective preventive strategies interventions

Language: Английский

Citations

0
Association of serum 25-hydroxyvitamin D with sleep disorders in individuals with prediabetes and diabetes: a prospective cohort study DOI Creative Commons
Guodong Liu, Haodong Li, Yi‐Cheng Ma

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: April 1, 2025

Sleep disorders are common globally and linked to various adverse health outcomes, including cardiovascular disease, type 2 diabetes, mental conditions. Emerging evidence suggests a potential role of serum 25-hydroxyvitamin D (25(OH)D) in regulating sleep. Individuals with prediabetes diabetes at an increased risk both vitamin deficiency sleep disorders, yet the relationship between these factors remains insufficiently studied. Utilizing data from UK Biobank, this study aims investigate association 25(OH)D concentrations individuals diabetes. We conducted cross-sectional 81,533 participants (mean age 59.6 [SD 7.1] years, comprising 41,275 males [50.6%] 40,278 females [49.4%]) followed by prospective 80,546 40,513 [50.3%] 40,033 [49.7%]) within same cohort, focusing on Baseline were categorized into four groups: severe (<25.0 nmol/L), moderate (25.0-50.0 insufficiency (50.0-75.0 sufficiency (≥75.0 nmol/L). Multivariable logistic regression Cox proportional hazards models used, adjusting for demographic, lifestyle, health-related confounders. Over average follow-up 12.8 we documented 2,704 cases found that higher significantly associated reduced disorder risk. In fully adjusted models, sufficient 48% (HR = 0.52; 95% CI: 0.41-0.65) 52% 0.48; 0.34-0.67). Subgroup analysis adequate improved especially people ≤60 years age, women, BMI≥30kg/m², those who had never smoked. This provides strong These findings suggest maintaining may offer strategy improve population.

Language: Английский

Citations

0
Higher dietary vitamin D intake influences brain and mental function in elderly Americans: a cross-sectional analysis DOI Creative Commons

Huizhen Chen,

Xing Pang,

Yuelong Huang

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: April 9, 2025

Vitamin D is known to have a potential impact on cognitive function and mental health. This study aims assess the association between dietary vitamin intake performance, as well depression, in an elderly U.S. population. Data from National Health Nutrition Examination Survey (NHANES) 2013-2014 were analyzed. A total of 1,344 participants categorized into three tertiles based their (D2 + D3). Cognitive was measured using Consortium Establish Registry for Alzheimer's Disease (CERAD) test, Digit Symbol Substitution Test (DSST), Animal Fluency Test, while depression assessed through Patient Questionnaire-9 (PHQ-9). Adjustments made confounding variables, including age, sex, race, education, physical activity level, other factors. After adjustment confounders, individuals 3rd tertile (≥4.9 mcg/day) had significantly reduced odds low performance CERAD test (OR: 0.77, 95% CI: 0.57-0.98; p = 0.031) 0.63, 0.49-0.85; 0.013) compared 1st (≤2.4 mcg/day). Similarly, lower (PHQ-9 score > 4) after 0.68, 0.48-0.99; 0.046). Our findings suggest that associated with improved depressive symptoms individuals. However, further longitudinal studies are needed establish causality explore underlying mechanisms.

Language: Английский

Citations

0
Serum 25(OH)D levels and obstructive sleep apnea syndrome severity in patients without comorbidities: a systematic review and meta-analysis DOI Creative Commons
Marco Serafin,

Martina Vaninetti,

Ismahan Mohamed

et al.

Sleep And Breathing, Journal Year: 2024, Volume and Issue: 29(1)

Published: Dec. 9, 2024

The aim of the present systematic review was to corroborate existing evidence on how serum25(OH)D levels affect obstructive sleep apnea syndrome (OSAS) severity in absence comorbidities. From inception May 2024, PubMed, Scopus, and Embase electronic databases were systematically screened identify randomized controlled trials (RCTs), quasi-RCTs, prospective, retrospective studies. A strict search protocol applied following application PROSPERO, under registration number CRD42023468744. formulated question based PICO process was: "how do OSAS or result enhanced function?". Collected results finally reviewed for meta-analysis quality assessment according ROBINS-I tool. Data from 24 studies pooled divided into 15 case-control 9 cross-sectional All involved a total 2640 subjects 933 healthy subjects. underwent qualitative analysis whereas only 20 collected meta-analysis. Mild showed 25(OH)D non-statistically significant (P = 0.12) than patients moderate 0.004) severe < 0.001) differed significantly control groups. Meta-regression suggested that correlated inversely deficiency serum levels. Qualitative Egger's test revealed an elevated risk bias but low presence publication bias, respectively. Serum observed be proportional without coexisting morbidities. mild not different non-OSAS patients, suggesting vitamin supplementation improve potential disorders.

Language: Английский

Citations

0