
Respiratory Research, Journal Year: 2025, Volume and Issue: 26(1)
Published: April 13, 2025
Chronic insomnia and obstructive sleep apnea commonly co-occur. Few studies have explored the neurophysiological neurocognitive characteristics of COMISA, which could help guide improving treatment diagnostic tools determining novel therapeutic targets. This study aims to explore COMISA using electroencephalographic (EEG) spectral analysis subjective objective measurements. Participants were from our community recruited OSA-insomnia-COMISA cohort with 206 included for current including 74 chronic insomniacs (CIs), 55 OSA patients 77 patients. Standard polysomnography (PSG) multiple latency tests (MSLTs) recorded used obtain relative EEG power in each stage during PSG session MSLTs. A series conducted evaluate executive function, attention, retrospective prospective memory meta-cognition. In MSLTs, showed combined both CIs OSA. Specifically, exhibited similar CIs, decreased delta increased alpha beta NREM stages, REM Similar profile OSA, Compared patients, worse subjectively measured attention meta-cognition related negative beliefs about uncontrollability danger worry (NEG), positively associated ISI scores. The overnight daytime MSLT appear be manifestation elements However, features NEG primarily affected by insomnia.
Language: Английский