EEG spectral analysis of nighttime sleep and daytime MSLTs and neurocognitive evaluations in subjects with co-morbid insomnia and OSA DOI Creative Commons
Yuan Shi,

Yuru Nie,

Fengyi Hao

et al.

Respiratory Research, Journal Year: 2025, Volume and Issue: 26(1)

Published: April 13, 2025

Chronic insomnia and obstructive sleep apnea commonly co-occur. Few studies have explored the neurophysiological neurocognitive characteristics of COMISA, which could help guide improving treatment diagnostic tools determining novel therapeutic targets. This study aims to explore COMISA using electroencephalographic (EEG) spectral analysis subjective objective measurements. Participants were from our community recruited OSA-insomnia-COMISA cohort with 206 included for current including 74 chronic insomniacs (CIs), 55 OSA patients 77 patients. Standard polysomnography (PSG) multiple latency tests (MSLTs) recorded used obtain relative EEG power in each stage during PSG session MSLTs. A series conducted evaluate executive function, attention, retrospective prospective memory meta-cognition. In MSLTs, showed combined both CIs OSA. Specifically, exhibited similar CIs, decreased delta increased alpha beta NREM stages, REM Similar profile OSA, Compared patients, worse subjectively measured attention meta-cognition related negative beliefs about uncontrollability danger worry (NEG), positively associated ISI scores. The overnight daytime MSLT appear be manifestation elements However, features NEG primarily affected by insomnia.

Language: Английский

Comorbid Insomnia and Sleep Apnea DOI
Alexander Sweetman, Leon Lack, Megan Crawford

et al.

Sleep Medicine Clinics, Journal Year: 2022, Volume and Issue: 17(4), P. 597 - 617

Published: Oct. 9, 2022

Language: Английский

Citations

21
Prevalence and clinical aspects of obstructive sleep apnea in Parkinson disease: A meta‐analysis DOI Creative Commons
Gianpaolo Maggi, Chiara Giacobbe, Federica Iannotta

et al.

European Journal of Neurology, Journal Year: 2023, Volume and Issue: 31(2)

Published: Nov. 3, 2023

Abstract Background and Purpose Obstructive sleep apnea (OSA) frequently occurs in Parkinson Disease (PD), probably caused by upper airway dysfunctions or shared pathogenetic mechanisms. OSA may precede PD diagnosis worsen throughout its course, but relationship with clinical features dopaminergic medication remains unclear. This meta‐analysis aimed to provide a reliable estimate of prevalence the population (PD‐OSA) clarify associated factors help clinicians understanding underlying pathophysiological Methods A systematic literature search was performed up April 2023 using PubMed, Scopus, PsycINFO databases. Articles were included if they provided data on patients without OSA. Pooled for PD‐OSA calculated proportions participants diagnosed Demographic explored comparing Results Seventeen studies meta‐analysis. 45% total sample 1448 older age, male sex, higher body mass index (BMI), more severe motor disturbances periodic limb movements, reduced risk rapid eye movement behavior disorder, intake dopamine agonists, worse excessive daytime sleepiness. No emerged cognitive functioning neuropsychiatric manifestations. Conclusions affects nearly half as secondary outcome predisposing such age BMI addition PD‐related impairment. Future should focus determining impact both development PD‐OSA.

Language: Английский

Citations

12
A Scoping Review of Sleep Apnea: Where Do We Stand? DOI Creative Commons
Rahim Hirani, Abbas Smiley

Life, Journal Year: 2023, Volume and Issue: 13(2), P. 387 - 387

Published: Jan. 31, 2023

Obstructive sleep apnea (OSA), a condition in which there is recurrent collapse of the upper airway while sleeping, widespread disease affecting 5% to 10% people worldwide. Despite several advances treatment modalities for OSA, morbidity and mortality remain concern. Common symptoms include loud snoring, gasping air during sleep, morning headache, insomnia, hypersomnia, attention deficits, irritability. Obese individuals, male gender, older age (65+), family history, smoking, alcohol consumption are well recognized risk factors OSA. This holds ability increase inflammatory cytokines, cause metabolic dysfunction, sympathetic output, all exacerbate OSA due their effect on cardiovascular system. In this review, we discuss its brief factors, complications, modalities, role clinicians curbing risk.

Language: Английский

Citations

11
Symptom content analysis of OSA questionnaires: time to identify and improve relevance of diversity of OSA symptoms? DOI
Christophe Gauld, Sébastien Baillieul, Vincent Martin

et al.

Journal of Clinical Sleep Medicine, Journal Year: 2024, Volume and Issue: 20(7), P. 1105 - 1117

Published: Feb. 29, 2024

Obstructive sleep apnea (OSA) is a heterogeneous condition covering many clinical phenotypes in terms of the diversity symptoms. Patient-based OSA screening questionnaires used routine practice contain significantly varying contents that can impact reliability and validity screening. We investigated to what extent common patient-based differ or overlap their item content by conducting rigorous, methodical, quantified analysis.

Language: Английский

Citations

4
Association of co-morbid insomnia and sleep apnoea symptoms with all-cause mortality: Analysis of the NHANES 2005-2008 data. DOI
Alexander Sweetman, Bastien Lechat, Sarah Appleton

et al.

Sleep Epidemiology, Journal Year: 2022, Volume and Issue: 2, P. 100043 - 100043

Published: Aug. 11, 2022

Language: Английский

Citations

18
Factors Associated With Residual Apnea-Hypopnea Index Variability During CPAP Treatment DOI Creative Commons

Anaïs Rossetto,

Alphanie Midelet, Sébastien Baillieul

et al.

CHEST Journal, Journal Year: 2023, Volume and Issue: 163(5), P. 1258 - 1265

Published: Jan. 13, 2023

Language: Английский

Citations

11
Impact of Preoperative Daytime Sleepiness and Insomnia on Therapy Adherence and Neurostimulation Amplitude in Unilateral Hypoglossal Nerve Stimulation DOI Creative Commons
Johannes Pordzik, Katharina Ludwig, Christian Ruckes

et al.

Nature and Science of Sleep, Journal Year: 2025, Volume and Issue: Volume 17, P. 251 - 259

Published: Feb. 1, 2025

Introduction: Average adherence to hypoglossal nerve stimulation (HGNS) therapy is more than 5 h/night. Reported data on HGNS often based studies that performed in-lab titration of the neurostimulation parameters and may therefore not represent real-world outcomes. Adherence a major determinant success this kind therapy. Factors with potential influence should be further elucidated. The aims study were investigate 1) details regarding under 2) possible association between age, insomnia, daytime sleepiness, polysomnography (PSG)-based metrics, HGNS-therapy adherence. Methods: Forty-three consecutive patients detailed information about time included. About 225 ± 191 days after implantation, PSG without any was performed. assessed by interrogating impulse generator's at time. Patient-reported insomnia using severity index (ISI) Epworth Sleepiness scale (ESS) used assess sleepiness before treatment. Results: An increased in setting 48.72 14.74 hours per week (6.96 night) found. A strong negative correlation preoperative ESS score (r = - 0.43; p< 0.005) Neither pre-operative nor had impact amplitude. positive age therapeutic amplitude levels could shown. Discussion: In cohort, average much higher previously reported. We provide evidence excessive seriously impair Keywords: obstructive sleep apnea, stimulation, adherence, airway pressure

Language: Английский

Citations

0
Insomnia features and patient-reported daytime sleepiness in patients with obstructive sleep apnea DOI Creative Commons
Haralampos Gouveris,

Alica Deiß,

Berit Hackenberg

et al.

Sleep Medicine, Journal Year: 2025, Volume and Issue: 129, P. 292 - 296

Published: Feb. 27, 2025

Language: Английский

Citations

0
Performance of Four Screening Tools for Identifying Obstructive Sleep Apnea Among Patients with Insomnia DOI Creative Commons
Chuan Shi, Yuxin Wang, Jinmei Luo

et al.

Nature and Science of Sleep, Journal Year: 2025, Volume and Issue: Volume 17, P. 379 - 390

Published: March 1, 2025

Co-morbid insomnia and sleep apnea are common in clinical practice. The existing OSA screening tools have not been fully validated populations, items measuring daytime function may be interfered with the presence of insomnia. This study aims to validate performance four commonly used among individuals without A cross-sectional survey was conducted suspected referred for studies from December 2021 2023. All participants completed Insomnia Severity Index (ISI) scale, STOP-Bang, Epworth Sleepiness Scale (ESS), Berlin questionnaire, NoSAS score. Clinical defined as an ISI 15 or more. Performance primarily assessed by sensitivity, specificity, receiver operating characteristic (ROC) curve. total 1266 (26% females, age 46.4 ± 12.4 years) were included study. prevalence apnea-hypopnea index (AHI) ≥15/h 48% 52% (n=313) non-insomnia (n=953) group, respectively (P>0.05). In insomnia, ESS, questionnaire demonstrated higher sensitivity but lower specificity. Using conventional cutoffs, STOP-Bang had highest level (93.2%, 95% CI 87.6-96.5%), while specificity (67.7%, 59.9-74.6%) identifying AHI ≥15/h. outperformed ESS areas under ROC curve >0.7 at all levels severity. Youden's maximized score 4 7 NoSAS. incorporating evaluation is altered Under preferred tool due its high sensitivity.

Language: Английский

Citations

0
Research Progress on Insomnia and OSA in Patients with Type 2 Diabetes Mellitus DOI

靖威 郑

Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(03), P. 1145 - 1154

Published: Jan. 1, 2025

Language: Английский

Citations

0