Analytical Chemistry,
Journal Year:
2022,
Volume and Issue:
94(48), P. 16847 - 16854
Published: Nov. 16, 2022
Several
groups
have
recently
explored
the
idea
of
developing
electrochemical
paper-based
wearable
devices,
specifically
targeting
metabolites
in
sweat.
While
these
sensors
potential
to
provide
a
breadth
analytical
information,
there
are
several
key
challenges
address
before
can
be
widely
adopted
for
clinical
interventions.
Toward
this
goal,
we
describe
development
sensor
detection
Staphylococcus
aureus.
Enabling
application,
report
describes
use
paper-derived
carbon
electrodes,
which
were
modified
with
thin
layer
sputtered
gold
(that
minimizes
lateral
resistivity
and
significantly
improves
electron
transfer
process)
chitosan
(used
as
binder,
offer
flexibility).
The
resulting
material
was
laser-patterned
applied
an
biosensor
controlled
(via
wireless
connection)
by
custom-built,
portable
potentiostat.
As
no
interference
observed
when
exposed
other
bacteria
or
common
metabolites,
system
(paper-derived
electrodes
+
potentiostat)
has
detect
presence
S.
aureus
skin,
commonly
misdiagnosed
mistreated
infection.
Biosensors,
Journal Year:
2022,
Volume and Issue:
12(8), P. 583 - 583
Published: July 29, 2022
Many
emerging
technologies
have
the
potential
to
improve
health
care
by
providing
more
personalized
approaches
or
early
diagnostic
methods.
In
this
review,
we
cover
smartphone-based
multiplexed
sensors
as
affordable
and
portable
sensing
platforms
for
point-of-care
devices.
Multiplexing
has
been
gaining
attention
recently
clinical
diagnosis
considering
certain
diseases
require
analysis
of
complex
biological
networks
instead
single-marker
analysis.
Smartphones
offer
tremendous
possibilities
on-site
detection
due
their
portability,
high
accessibility,
fast
sample
processing,
robust
imaging
capabilities.
Straightforward
digital
convenient
user
interfaces
support
networked
systems
individualized
monitoring.
Detailed
biomarker
profiling
provides
accurate
disease
limited
volume
collection.
Here,
assays
with
optical
electrochemical
components
are
covered.
Possible
wireless
wired
communication
actuators
wearable
integration
various
applications
discussed.
The
crucial
features
weaknesses
these
devices
critically
evaluated.
ACS Applied Materials & Interfaces,
Journal Year:
2022,
Volume and Issue:
14(3), P. 3838 - 3848
Published: Jan. 13, 2022
Wearable
electronic
medical
devices
measuring
continuous
biological
signals
for
early
disease
diagnosis
should
be
small
and
lightweight
consecutive
usability.
As
a
result,
there
has
been
an
increasing
need
new
energy
supply
systems
that
provide
power
without
any
interruption
to
the
operation
of
associated
with
use
conventional
batteries.
In
this
work,
we
developed
patch-type
self-charging
supercapacitor
can
measure
The
glucose
oxidase
coated
on
surface
microneedle-type
sensor
encounters
in
interstitial
fluids
human
body.
Electrons
created
by
oxidation
operate
self-powered
system
which
charging
begins
generation
potential
differences
electrodes.
11
mM
solution,
solid-state
supercapacitors
(SPSCs)
showed
density
0.62
mW/cm2,
resulted
supercapacitor.
produced
each
SPSC
drop
solution
was
higher
than
glucose-based
biofuel
cells.
Consequently,
all-in-one
sensor,
aid
Arduino
Uno
board
appropriate
programming,
effectively
distinguished
normal,
prediabetic,
diabetic
levels
from
0.5
mL
solutions
absorbed
laboratory
skin
model.
ACS Sensors,
Journal Year:
2022,
Volume and Issue:
7(10), P. 3169 - 3180
Published: Oct. 17, 2022
Easy
sample
collection,
physiological
relevance,
and
ability
to
noninvasively
longitudinally
monitor
the
human
body
are
some
of
key
attributes
wearable
sweat
sensors.
Examples
typically
include
reversible
sensors
or
an
array
single-use
embedded
in
specialized
microfluidics
for
temporal
analysis
sweat.
However,
evolving
this
field
a
level
that
truly
represents
"lab-on-skin"
technology
will
require
incorporation
advanced
functionalities
give
user
freedom
(1)
choose
precise
time
performing
(2)
select
from
within
device
condition-specific
analysis.
Here,
we
introduce
new
concepts
microfluidic
platforms
offer
such
capabilities.
The
described
involves
series
finger-actuated
pumps,
valves,
incorporated
soft,
microfluidics.
incoming
collects
inlet
chamber
can
be
analyzed
by
at
their
choosing.
On-demand
analyte
assessment
is
achieved
pulling
thin
tab
activate
pump
which
opens
valve
allows
pooled
enter
with
desired
analytes.
article
describes
thorough
characterization
platform
demonstrates
robustness
pumping,
valving,
sensing
aspects
under
conditions
mimicking
real-life
scenarios.
A
two-day-long
pilot
study
validates
system
illustrates
device's
on-demand,
longitudinal,
multianalyte
sensing.
Our
work
first
example
on-demand
capabilities
exciting
avenues
acquiring
insights
into
physiology.
Analytical Chemistry,
Journal Year:
2022,
Volume and Issue:
94(48), P. 16847 - 16854
Published: Nov. 16, 2022
Several
groups
have
recently
explored
the
idea
of
developing
electrochemical
paper-based
wearable
devices,
specifically
targeting
metabolites
in
sweat.
While
these
sensors
potential
to
provide
a
breadth
analytical
information,
there
are
several
key
challenges
address
before
can
be
widely
adopted
for
clinical
interventions.
Toward
this
goal,
we
describe
development
sensor
detection
Staphylococcus
aureus.
Enabling
application,
report
describes
use
paper-derived
carbon
electrodes,
which
were
modified
with
thin
layer
sputtered
gold
(that
minimizes
lateral
resistivity
and
significantly
improves
electron
transfer
process)
chitosan
(used
as
binder,
offer
flexibility).
The
resulting
material
was
laser-patterned
applied
an
biosensor
controlled
(via
wireless
connection)
by
custom-built,
portable
potentiostat.
As
no
interference
observed
when
exposed
other
bacteria
or
common
metabolites,
system
(paper-derived
electrodes
+
potentiostat)
has
detect
presence
S.
aureus
skin,
commonly
misdiagnosed
mistreated
infection.
