Multifunctional Polyoxovanadate-Based Covalent Organic Polymer for Bacteria-Infected Wound Therapy DOI
Yinuo Li, Liyan Zhao,

Manli Liu

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

The special pathological microenvironment of infected wounds (pathology weakly acidic, hypoxic, and overexpressed H2O2) provides fertile soil for the development disease. Tailoring treatment based on specific characteristics infectious (IME) has emerged as a novel direction in antimicrobial therapies. Here, polyoxovanadate (POV)-based covalent organic polymer (POV-Fc-COP) with inherent photothermal activity was facilely prepared via copolymerization 1,1′-bi(3-dimethylamino-1-oxo-2-enyl-ferrocene) (BDOEF) tris-NH2-modified POV (tris-V6O9), which nanovanadium oxide (V2O3 V2O5) core shell were generated directly during Michael addition–elimination reaction. unique structure composition impart pH-responsive peroxidase-like (POD-like) catalase-like (CAT-like) activities, concurrently, to POV-Fc-COP. Specifically, acid-activated mimicking-POD could consume H2O2 microenvironment, producing toxic •OH combat bacteria biofilms. vanadium consumes excessive acid, resulting an increase pH. Meanwhile, CAT-like transform excess expression into O2 relieve hypoxia induced by damage blood vessels facilitate wound healing. Additionally, synergistic amplified therapeutic effect triggered application laser irradiation facilitates rapid eradication biofilm, minimizing detrimental impacts bacterial proliferation IME, thereby accelerating restoration IME return normal state. Therefore, POV-Fc-COP dual-enzyme functionality not only utilize but also regulate significantly expediting healing bacteria-infected wounds. This study demonstrates simple method preparation intelligent platform programmed antibacterial antibiofilm formation, thus promoting while utilizing improving IME.

Language: Английский

Ratiometric fluorescent probe and smartphone-based visual recognition for H2O2 and organophosphorus pesticide based on Ce3+/Ce4+ cascade enzyme reaction DOI

Yaxin Li,

Shiwen Wu, Hongzhi Lu

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 469, P. 142577 - 142577

Published: Dec. 18, 2024

Language: Английский

Citations

2
Porous reticular Co@Fe metal–organic gel: dual–function simulated peroxidase nanozyme for both colorimetric sensing and antibacterial applications DOI

Meng Wang,

Xiaoguang Zhu,

Yannan Yin

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(22), P. 5418 - 5430

Published: Jan. 1, 2024

The novel material Co@Fe MOG was designed to treat infected wounds in wound healing. ROS induced by electron transfer between Fe 3+ /Fe 2+ and Co /Co the basis for colorimetric sensing non-antibiotic antibacterial activity.

Language: Английский

Citations

1
Metal‐organic Framework (MOF)‐Based Sensors for Mercury (Hg) Detection: Design Strategies and Recent Progress DOI
W. F. Mader, Q Zhang, Dongshan Xiang

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 21, 2024

Abstract Monitoring mercury (Hg) is critical for environmental and public health. Metal‐organic framework (MOF)‐based sensors demonstrate the advantage of high sensitivity rapid response. We summarize advances MOF Hg 2+ detection from perspective type role in sensors. First, we introduce three MOFs used sensors‐UIO, ZIF, MIL‐that have demonstrated superior performance. Then, discuss specifics MOF‐based terms recognition signal elements. Currently, elements include T‐rich aptamers, noble metal nanoparticles, central ions, organic functional groups inherent to MOFs. Sensors with fluorescence colorimetric signals are two main types optical detection. Electrochemical also been fabricated, but these less frequently reported, potentially due limited conductivity cycling stability Notably, dual‐signal mitigate background interference enhance accuracy Furthermore, facilitate portability user‐friendliness, portable devices such as microfluidics, paper‐based devices, smartphones developed detection, showcasing potential applications. address challenges related future outlook.

Language: Английский

Citations

1
Heavy metal pollutant detection using nanozymes DOI
Hamada A. A. Noreldeen, Hao‐Hua Deng, Wei Chen

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 403 - 421

Published: Jan. 1, 2024

Language: Английский

Citations

0
Multifunctional Polyoxovanadate-Based Covalent Organic Polymer for Bacteria-Infected Wound Therapy DOI
Yinuo Li, Liyan Zhao,

Manli Liu

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

The special pathological microenvironment of infected wounds (pathology weakly acidic, hypoxic, and overexpressed H2O2) provides fertile soil for the development disease. Tailoring treatment based on specific characteristics infectious (IME) has emerged as a novel direction in antimicrobial therapies. Here, polyoxovanadate (POV)-based covalent organic polymer (POV-Fc-COP) with inherent photothermal activity was facilely prepared via copolymerization 1,1′-bi(3-dimethylamino-1-oxo-2-enyl-ferrocene) (BDOEF) tris-NH2-modified POV (tris-V6O9), which nanovanadium oxide (V2O3 V2O5) core shell were generated directly during Michael addition–elimination reaction. unique structure composition impart pH-responsive peroxidase-like (POD-like) catalase-like (CAT-like) activities, concurrently, to POV-Fc-COP. Specifically, acid-activated mimicking-POD could consume H2O2 microenvironment, producing toxic •OH combat bacteria biofilms. vanadium consumes excessive acid, resulting an increase pH. Meanwhile, CAT-like transform excess expression into O2 relieve hypoxia induced by damage blood vessels facilitate wound healing. Additionally, synergistic amplified therapeutic effect triggered application laser irradiation facilitates rapid eradication biofilm, minimizing detrimental impacts bacterial proliferation IME, thereby accelerating restoration IME return normal state. Therefore, POV-Fc-COP dual-enzyme functionality not only utilize but also regulate significantly expediting healing bacteria-infected wounds. This study demonstrates simple method preparation intelligent platform programmed antibacterial antibiofilm formation, thus promoting while utilizing improving IME.

Language: Английский

Citations

0