Tuning Atomically Dispersed Metal Sites in Nanozymes for Sensing Applications

Angewandte Chemie International Edition, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Abstract Nanozymes with atomically dispersed metal sites (ADzymes), especially single‐atom nanozymes, have attracted widespread attention in recent years due to their unique advantages mimicking the active of natural enzymes. These nanozymes not only maximize exposure catalytic but also possess superior activity performance, achieving challenging reactions. position ADzymes as highly promising candidates field sensing and biosensing. This review summarizes classification properties ADzymes, systematically highlighting some typical regulation strategies involving central metal, coordination environment, etc., achieve catalytical activity, specificity, multifunctionality. Then, we present advances different fields, including colorimetry, fluorescence, electrochemistry, chemiluminescence, photoelectrochemistry, electrochemiluminescence. Taking advantage resultant show great potential goal sensitivity, selectivity accuracy for detection various targets. Specifically, underlying mechanisms terms signal amplification were discussed detail. Finally, current challenges perspectives on development advanced are discussed.

Language: Английский

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Biofunctional photoelectrochemical/electrochemical immunosensor based on BiVO4/BiOI-MWCNTs and Au@PdPt for alpha-fetoprotein detection

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 160, P. 108773 - 108773

Published: July 3, 2024

Language: Английский

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Target-regulated Ag2S/FeOOH heterojunction activity: a direct label-free photoelectrochemical immunosensor

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(2)

Published: Jan. 18, 2025

Language: Английский

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Tuning Atomically Dispersed Metal Sites in Nanozymes for Sensing Applications

Angewandte Chemie, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Abstract Nanozymes with atomically dispersed metal sites (ADzymes), especially single‐atom nanozymes, have attracted widespread attention in recent years due to their unique advantages mimicking the active of natural enzymes. These nanozymes not only maximize exposure catalytic but also possess superior activity performance, achieving challenging reactions. position ADzymes as highly promising candidates field sensing and biosensing. This review summarizes classification properties ADzymes, systematically highlighting some typical regulation strategies involving central metal, coordination environment, etc., achieve catalytical activity, specificity, multifunctionality. Then, we present advances different fields, including colorimetry, fluorescence, electrochemistry, chemiluminescence, photoelectrochemistry, electrochemiluminescence. Taking advantage resultant show great potential goal sensitivity, selectivity accuracy for detection various targets. Specifically, underlying mechanisms terms signal amplification were discussed detail. Finally, current challenges perspectives on development advanced are discussed.

Language: Английский

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Photoelectrochemical Biosensor Based on TiO₂/P5FIn with a Cascade Amplification Strategy for Simultaneous Detection of GSH and E2 Analytes of Ovarian Cancer

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

In this work, a photoelectrochemical (PEC) sensor for ovarian cancer detection was constructed based on TiO2/poly(5-formylindole) (P5FIn)heterojunction using cascade amplification. The combined of multiple markers instead single mode can improve diagnostic accuracy. photoelectron conversion efficiency and photocurrent response were significantly improved by the reaction detector glutathione (GSH) with cystine. 17β-Estradiol (E2) had negative effect PEC response, reducing signal, ultimately realizing sensitive GSH E2. good performance E2, linear range (LDR) 0.5–1000 μM, limits (LOD) 0.167 μM 0.1224 pM, respectively, 0.0003671–36.71 nM. Meanwhile, also has analytical capability, signal amplification strategy potential development prospect in disease detection.

Language: Английский

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Recent advances in MOF-modified electrochemical sensor for point-of-care detecting cardiac biomarkers

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118277 - 118277

Published: April 1, 2025

Language: Английский

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Liposome-embedded PtCu nanozymes for improved immunoassay of accurate myocardial infarction

Talanta, Journal Year: 2024, Volume and Issue: 279, P. 126576 - 126576

Published: July 15, 2024

Language: Английский

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Nature inspired metal-organic frameworks: Challenges, innovations, and prospects

Polyhedron, Journal Year: 2025, Volume and Issue: unknown, P. 117545 - 117545

Published: April 1, 2025

Language: Английский

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Single-Atom Ruthenium Nanozyme-Induced Signal Amplification Strategy in Photoelectrochemical Aptasensor for Ultrasensitive Detection of Chloramphenicol

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 268, P. 116917 - 116917

Published: Nov. 6, 2024

Language: Английский

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Nanozyme-triggered polymerization amplification strategy for constructing highly sensitive surface plasmon resonance immunosensing

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110333 - 110333

Published: Aug. 1, 2024

Language: Английский

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