Gold Nanoparticles Decorated CoAl LDH Monolayer: A Peroxidase-Like Nanozyme for Sensitive Colorimetric Detection of Acetylcholinesterase and Inhibitors DOI

Xingzhi Yu,

Limei Zhang, Xun He

et al.

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

Monitoring acetylcholinesterase (AChE) activity and its inhibitor is crucial yet challenging for the early diagnosis treatment of neurological diseases. In this study, we present Au nanoparticle decorated CoAl layered double hydroxide monolayer (Au@CoAl-LDH-m) as a peroxidase-like (POD) nanozyme sensitive colorimetric detection AChE inhibitor, thiamine pyrophosphate (TPP). Remarkably, Au@CoAl-LDH-m can catalyze oxidation chromogenic substrates through POD-like activity, which effectively inhibited by thiocholine (TCh, catalytic product AChE), thereby enabling TPP visible readout. The approach provides highly specificity assay with broader linear response range (1-100 mU mL

Language: Английский

Synthesis of Ternary Layered Carbide M3SnC2 (M=Ti, Zr, Hf) for Microwave Absorption DOI

Miaoqing Chen,

Yubin Zhang, Zaisheng Zhu

et al.

Journal of Alloys and Compounds, Journal Year: 2025, Volume and Issue: unknown, P. 178750 - 178750

Published: Jan. 1, 2025

Language: Английский

Citations

0
Colorimetric Detection of Acetylcholinesterase and its Specific Inhibitor Using Ultra-Small Platinum Nanoparticles Decorated with the Metal-Organic Framework (Mof) Pcn-224-Pt DOI

Weiyi Bai,

Xingzhi Yu,

Qing Li

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

1
Gold Nanoparticles Decorated CoAl LDH Monolayer: A Peroxidase-Like Nanozyme for Sensitive Colorimetric Detection of Acetylcholinesterase and Inhibitors DOI

Xingzhi Yu,

Limei Zhang, Xun He

et al.

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

Monitoring acetylcholinesterase (AChE) activity and its inhibitor is crucial yet challenging for the early diagnosis treatment of neurological diseases. In this study, we present Au nanoparticle decorated CoAl layered double hydroxide monolayer (Au@CoAl-LDH-m) as a peroxidase-like (POD) nanozyme sensitive colorimetric detection AChE inhibitor, thiamine pyrophosphate (TPP). Remarkably, Au@CoAl-LDH-m can catalyze oxidation chromogenic substrates through POD-like activity, which effectively inhibited by thiocholine (TCh, catalytic product AChE), thereby enabling TPP visible readout. The approach provides highly specificity assay with broader linear response range (1-100 mU mL

Language: Английский

Citations

0