Ultrasensitive ECL immunoassay for CA15-3 via self-enhanced L012-loaded ZnNi-MOF as an emitter and CeO2-Pt as a co-reaction accelerator DOI
Cui Chen,

Naxin Liu,

Qiurui Nian

et al.

Talanta, Journal Year: 2024, Volume and Issue: 283, P. 127120 - 127120

Published: Oct. 30, 2024

Language: Английский

Electrochemiluminescence Resonance Energy Transfer Biosensor for the Human-Associated Clade of Streptococcus suis Based on Prereduction-Enhanced Yttrium MOFs DOI

Can Hu,

Hongjun Xiang,

Yashi Yin

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Streptococcus suis, a significant zoonotic pathogen, annually caused substantial economic losses in the swine industry and had intensified threat to public health due recent emergence of human-associated clade. In this study, we discovered that rare-earth metal-based metal-organic frameworks (Y-BTC) possessed excellent ECL capabilities. After prereduction at high voltage, its intensity was enhanced by two times. Subsequently, developed an efficient CRISPR/Cas12a-mediated electrochemiluminescence resonance energy transfer (ECL-RET) biosensor utilizing Y-BTC for detection S. suis employed as ECL-RET donor emitter, spherical nucleic acid Au NP utilized receptor. presence target, isothermal amplification triggered generate large number amplicons, which subsequently activated trans-cleavage activity Cas12a. Cas12a cleaved shell on surface NPs, reducing spatial distance between NPs electrostatic adsorption, thereby quenching via ECL-RET. Consequently, targets can be observed reduced signal. The sensor exhibited range 25 pM 50 nM, with limit low 17 pM. practical utility verified through actual sample testing. Our proposed sensing strategy provides new avenue sensitive suis. universality has also been demonstrated using Fusobacterium nucleatum, Salmonella pullorum, Listeria monocytogenes, holding great promise field food safety health.

Language: Английский

Citations

0
Design strategies and applications of electrochemiluminescence from metal nanoclusters DOI
Tingting Li, J. Sui,

Weinan Dong

et al.

Inorganic Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We summarize the design strategies for improving ECL of metal nanoclusters, including 1. aggregation-induced emission; 2. anodic pre-oxidation; 3. self-loading; 4. Anionic substitution; 5. ion doping; 6. valence engineering.

Language: Английский

Citations

0
Multi-element transition metal electrochemiluminescence system based on efficient quenching strategy for sensitive detection of glial fibrillary acidic protein DOI

Fangqin Han,

Chunfang Cheng,

Jingyu Zhao

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: unknown, P. 137767 - 137767

Published: April 1, 2025

Language: Английский

Citations

0
Ultrasensitive ECL immunoassay for CA15-3 via self-enhanced L012-loaded ZnNi-MOF as an emitter and CeO2-Pt as a co-reaction accelerator DOI
Cui Chen,

Naxin Liu,

Qiurui Nian

et al.

Talanta, Journal Year: 2024, Volume and Issue: 283, P. 127120 - 127120

Published: Oct. 30, 2024

Language: Английский

Citations

1