CRISPR/Cas12a-based transition state molecular switch for low-background detection of HPV-16 on a microfluidic platform DOI

Boren Sui,

Chunhong Liu, Zhiwei Sun

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 311, P. 143556 - 143556

Published: April 28, 2025

Language: Английский

Advances in Functional Nucleic Acid SERS Sensing Strategies DOI
Lin Shi, Yukang Liu, Xiaodong Li

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

Functional nucleic acids constitute a distinct category of that diverge from conventional acid amplification methodologies. They are capable forming intricate hybrid structures through Hoogsteen and reverse hydrogen bonding interactions between double-stranded single-stranded DNA, thereby broadening the spectrum DNA interactions. In recent years, functional DNA/RNA-based surface-enhanced Raman spectroscopy (SERS) has emerged as potent platform ultrasensitive multiplexed detection variety analytes interest. This review aims to elucidate operational principles several in SERS detection, including DNAzymes, G-quadruplexes, aptamers, CRISPR, origami etc., alongside design methodologies practical applications sensing. Initially, an overview is summarized encompassing structural attributes sensing mechanisms inherent diverse DNA/RNA. Following this, various innovative strategies for constructing acid-based sensors illustrated detail, aimed at improving present capabilities. A comprehensive summing up then conducted on these crucial fields, such disease diagnosis, environmental monitoring, food safety with particular focus sensitivity, specificity, analytical versatility. Finally, conclusive remarks offered along exploration existing challenges prospective avenues future research this developed field.

Language: Английский

Citations

6
CRISPR/Cas-Based Nanobiosensor Using Plasmonic Nanomaterials to Detect Disease Biomarkers DOI Creative Commons
Jin‐Ha Choi, Jinho Yoon,

Meizi Chen

et al.

BioChip Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Language: Английский

Citations

0
Hybridization chain reaction and CRISPR/Cas12a-integrated biosensor for precise Ago2 detection DOI
Qiang Tang, Jiayi Zhang, Jianhu Pang

et al.

Bioelectrochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 108975 - 108975

Published: March 1, 2025

Language: Английский

Citations

0
A biosensor based on TiO2/Sb2S3 nanorod array for visible-light induced photoelectrochemical detection of miRNA-155 DOI
Di Zhao, Xiaoqing Pan, Jinghan Zhao

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113731 - 113731

Published: April 1, 2025

Language: Английский

Citations

0
Innovative Applications of SERS in Precision Medicine: In Situ and Real-Time Live Imaging DOI

Biqing Chen,

Jiayin Gao,

Haizhu Sun

et al.

Talanta, Journal Year: 2025, Volume and Issue: 294, P. 128225 - 128225

Published: April 28, 2025

Language: Английский

Citations

0
CRISPR/Cas12a-based transition state molecular switch for low-background detection of HPV-16 on a microfluidic platform DOI

Boren Sui,

Chunhong Liu, Zhiwei Sun

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 311, P. 143556 - 143556

Published: April 28, 2025

Language: Английский

Citations

0