Metal covalent organic frameworks-based laccase-like nanozyme for oxidative degradation and identification of phenolic pollutants

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 487, P. 137142 - 137142

Published: Jan. 7, 2025

Language: Английский

---

Aptamer-regulated colorimetric and electrochemical dual-mode sensor for the detection of uranyl ions utilizing AuNCs@COF composite

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(5)

Published: April 14, 2025

Language: Английский

---

Bioinspired Iron Porphyrin Covalent Organic Frameworks-Based Nanozymes Sensor Array: Machine Learning-Assisted Identification and Detection of Thiols

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(51), P. 71048 - 71059

Published: Dec. 12, 2024

Given the crucial role of thiols in maintaining normal physiological functions, it is essential to establish a high-throughput and sensitive analytical method identify quantify various accurately. Inspired by iron porphyrin active center natural horseradish peroxidase (HRP), we designed synthesized two covalent organic frameworks (Fe-COF-H Fe-COF-OH) with notable peroxidase-like (POD) activity, capable catalyzing 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB three distinct absorption peaks. Based on these, six-channel nanozyme colorimetric sensor array was constructed, which could map specific fingerprints thiols. Subsequently, machine learning techniques, including supervised linear discriminant analysis (LDA), decision trees (DT) artificial neural networks (ANN), unsupervised hierarchical cluster (HCA), ensemble random forests (RF), were used for precise identification complex systems, detection limit as low 50 nM. Significantly, demonstrated strong potential practical applications, analyzing homocysteine (Hcy) human serum, mercaptoacetic acid (TGA) depilatory creams, glutathione (GSH) cell lysates, thereby showing promise use disease diagnosis.

Language: Английский

---

Tetrapyrrole Organics-Modified Cerium Nanozyme with Enhanced Oxidase-Like Activity for Integration of Detection and Degradation of Antibiotic

Talanta, Journal Year: 2024, Volume and Issue: 286, P. 127472 - 127472

Published: Dec. 26, 2024

Language: Английский

---