Trends in Aptasensing and the Enhancement of Diagnostic Efficiency and Accuracy DOI
Mohammad A. Ansari, Damini Verma,

Mohd-Akmal Hamizan

et al.

ACS Synthetic Biology, Journal Year: 2025, Volume and Issue: 14(1), P. 21 - 40

Published: Jan. 6, 2025

The field of healthcare diagnostics is navigating complex challenges driven by evolving patient demographics and the rapid advancement new technologies worldwide. In response to these challenges, biosensors offer distinctive advantages over traditional diagnostic methods, such as cost-effectiveness, enhanced specificity, adaptability, making their integration with point-of-care (POC) platforms more feasible. recent years, aptasensors have significantly evolved in capabilities through emerging microfluidics, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems, wearable devices, machine learning (ML), driving progress precision medicine global solutions. Moreover, advancements not only improve accuracy but also hold potential revolutionize early detection, reduce costs, outcomes, especially resource-limited settings. This Account examines key advancements, focusing on how scientific breakthroughs, including artificial intelligence (AI), improved sensitivity precision. Additionally, has enabled real-time monitoring data analysis, fostering advances personalized healthcare. Furthermore, commercialization aptasensor could increase availability clinical settings support use widespread solutions for health challenges. Hence, this review discusses technological improvements, practical uses, prospects while surrounding standardization, validation, interdisciplinary collaboration application. Finally, ongoing efforts address are ensure that can be effectively implemented diverse systems.

Language: Английский

Trends in Aptasensing and the Enhancement of Diagnostic Efficiency and Accuracy DOI
Mohammad A. Ansari, Damini Verma,

Mohd-Akmal Hamizan

et al.

ACS Synthetic Biology, Journal Year: 2025, Volume and Issue: 14(1), P. 21 - 40

Published: Jan. 6, 2025

The field of healthcare diagnostics is navigating complex challenges driven by evolving patient demographics and the rapid advancement new technologies worldwide. In response to these challenges, biosensors offer distinctive advantages over traditional diagnostic methods, such as cost-effectiveness, enhanced specificity, adaptability, making their integration with point-of-care (POC) platforms more feasible. recent years, aptasensors have significantly evolved in capabilities through emerging microfluidics, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems, wearable devices, machine learning (ML), driving progress precision medicine global solutions. Moreover, advancements not only improve accuracy but also hold potential revolutionize early detection, reduce costs, outcomes, especially resource-limited settings. This Account examines key advancements, focusing on how scientific breakthroughs, including artificial intelligence (AI), improved sensitivity precision. Additionally, has enabled real-time monitoring data analysis, fostering advances personalized healthcare. Furthermore, commercialization aptasensor could increase availability clinical settings support use widespread solutions for health challenges. Hence, this review discusses technological improvements, practical uses, prospects while surrounding standardization, validation, interdisciplinary collaboration application. Finally, ongoing efforts address are ensure that can be effectively implemented diverse systems.

Language: Английский

Citations

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