Electrochemical Detection of Per- and Polyfluoroalkyl Substances: A Review

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114653 - 114653

Published: March 1, 2025

Language: Английский

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Rapid Single-Step Detection of Polyfluoroalkyl Substances (PFAS) Using Electropolymerized Phenoxazine Dyes

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(44), P. 17506 - 17516

Published: Oct. 15, 2024

Per- and polyfluoroalkyl substances (PFAS) are highly stable ubiquitous contaminants that have been recently added to the list of regulated chemicals. While methods for PFAS detection exist, analysis is difficult, involving a tedious protocol expensive instrumentation. Here, we demonstrate first implementation phenoxazine dye as sensing probe facilitates rapid inexpensive representative PFAS, e.g., perfluorooctanesulfonic acid (PFOS) perfluorooctanoic (PFOA), at sensitivity levels covering established Environmental Protection Agency (EPA) limits. The method comprises an electrode modified with redox film Meldola blue (MB) in its electropolymerized form (

Language: Английский

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Per- and Poly-fluoroalkyl Substances as Forever Chemicals in Drinking Water: Unraveling the Nexus with Obesity and Endocrine Disruption – A Mini Review

Heliyon, Journal Year: 2025, Volume and Issue: 11(4), P. e42782 - e42782

Published: Feb. 1, 2025

Per- and Poly-fluoroalkyl substances (PFASs) are among the that have been widely employed across world due to their distinct features. These chemicals' great stability in environment capacity be released from consumer goods demonstrated existence all matrices. Additionally, world's attention has drawn these substances' direct relation human health recent years. This research aimed unravel nexus of PFASs with obesity endocrine disruption as a comprehensive review. Studies shown drinking water is primary way which humans exposed PFASs. As result, it become difficult determine how contaminated compounds impacts affect health. Through various routes, metabolic processes, possible effects on hypothalamus-pituitary-thyroid axis, chemicals increase incidence obesity, particularly during crucial growth phases. Another negative impact glands' function, for controlling body's physiological functions. leads alterations hormone production. The exposure include secondary hyperparathyroidism, non-alcoholic fatty liver, diabetes, cardiovascular illnesses, reproductive abnormalities, infertility. Because characteristics, including propensity propagate through food chain, accumulate biomagnify, ultimately pose threat life, replace remove chemicals.

Language: Английский

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Dual-modal detection of perfluorooctanoic acid (PFOA) using a single polymer platform: ACQ and IDA approaches

RSC Applied Polymers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The fluorescent PPMI polymer exhibits aggregation-caused quenching (ACQ) and indicator displacement assay (IDA) “turn-on” responses towards perfluorooctanoic acid in aqueous media, with limits of detection 0.21 μM 16.1 nM, respectively.

Language: Английский

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Rapid Detection of Perfluorodecanoic Acid and Perfluorooctanesulfonic Acid in Foods Using a Molecularly Imprinted Poly(o-phenylenediamine)/Modified Glassy Carbon Electrode

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

In the current work, a modified glassy carbon electrode (GCE) with excellent conductivity was prepared by drop-coating carboxymethyl cellulose (CMC) and multiwalled nanotubes (MWCNTs) on GCE surface. On this basis, two highly selective molecularly imprinted sensors (MIP@PFDA/modified MIP@PFOS/modified GCE) were separately obtained in situ electropolymerization of o-phenylenediamine (o-PD) perfluorodecanoic acid (PFDA) perfluorooctanesulfonic (PFOS) as templates. Under optimal conditions, sensitive quantification methods linearity ranges 0.1–1000 ng/mL 0.05–900 developed via differential pulse voltammetry using [Fe(CN)6]3–/4– redox probe. The detection limit values PFDA PFOS low 0.041 0.015 ng/mL, respectively. Both also presented great stability selectivity coexistence other interferences. Lastly, three food samples utilized to verify validity applicability recoveries 89.97%–112.27%, confirming its potential for per- polyfluoroalkyl substances (PFASs) monitoring complex matrix.

Language: Английский

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Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications

AIMS environmental science, Journal Year: 2025, Volume and Issue: 12(2), P. 321 - 351

Published: Jan. 1, 2025

Language: Английский

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Novel Nanozymes with Sample Pretreatment Function for Specific Multimodal Detection of Perfluorooctanesulfonate

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 10, 2025

Perfluorooctanesulfonate (PFOS), a ubiquitous and persistent organic pollutant, poses severe health risks due to its bioaccumulation recalcitrance. Despite existing detection methods, the need for rapid, sensitive, cost-effective PFOS quantification remains unmet, particularly on-site mass sample analysis. Here, we introduce an innovative "three-in-one" multifunctional nanohybrid, Fe3O4@MON-F@Ru, which revolutionizes of through novel integration nanozymes microporous networks (MONs). This nanohybrid enables sensitive colorimetric photothermal signaling detection, addressing long-standing challenge selectivity in nanozyme-based analytical methods. The Fe3O4 core magnetic separation, while fluorinated MONs shell specifically interacts with F-F bonding electrostatic forces, concurrently serving as high-density carrier Ru nanozymes. presence significantly inhibits catalytic activity, offering rapid specific method limit low 15.4 nM. Additionally, based on near-infrared (NIR) laser-driven properties oxidized 3,3',5,5'-tetramethylbenzidine (TMB), analysis was also established. study not only advances design integrated pretreatment capabilities but pioneers portable, dual-signaling sensing strategy profound implications environmental monitoring public safety.

Language: Английский

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A review on the latest frontiers in water quality in the era of emerging contaminants: A focus on perfluoroalkyl compounds

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 126402 - 126402

Published: May 1, 2025

Water quality is continuously deteriorating due to various drivers of change, including rapid urbanization, industrial development, inadequate sanitation facilities, and climate change. Furthermore, the detection newly monitored emerging contaminants, which are not always fully regulated, has turned water pollution into a "time bomb" on verge exploding. While laboratory-based methodologies offer significant advantages, such as high sensitivity, accuracy, selectivity, steady growth sensors soft for on-line on-site monitoring purposes cannot be overlooked. This review focuses sensor innovations over past five years, providing an in-depth comparison between classical methods novel advanced technologies. It also explores current strategies controlling potential regulation limits, solutions overcome transboundary challenges management. Special attention given class perfluoroalkyl compounds (PFAS), ubiquitously found in matrices. For them, traditional technologies presented evaluate their reliability future off-lab applications.

Language: Английский

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Per- and poly-fluoroalkyl substances (PFAS) sensing: A focus on representatively sampling soil vadose zones linked to nano-sensors

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 284, P. 116932 - 116932

Published: Aug. 27, 2024

Per- and poly-fluoroalkyl substances (PFAS) are a group of organo-fluorine compounds that have been broadly used in consumer industrial products spanning virtually all sectors. They can be found as surfactants, coatings liners, polymer additives, fire retardants, adhesives, many more. The chemical stability the carbon fluorine bond amphiphilic nature PFAS result their persistence mobility environment via soil porewater, surface water groundwater, with potential for adverse effects on human health. There is an emergent increasing requirement fast, low-cost, robust, portable methods to detect PFAS, especially field. may thousands present at extremely low concentration (0.01-250 ppb) require measurement, traditional technologies continuous environmental sensing challenged due complexity chemistry. This paper presents comprehensive review potentially rapid measurement methods, focused techniques representative sampling porewater from contaminated soil, approaches pre-treatment samples eliminate these interferences ready PFAS-detecting sensors. discusses selectivity, key factor underlying performance, explores interactions between various nano-sensors discussed categorized terms detection mechanism (electrochemical optical). aims provide guidance outline current challenges implications future routine linked collection, achieve more selective effective

Language: Английский

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Effects of Fabrication Parameters on the Mechanical and Sensing Properties of Molecularly Imprinted Polymers (MIPs) for the Detection of Per- and Polyfluoroalkyl Substances (PFAS)

ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: 6(16), P. 9914 - 9921

Published: Aug. 14, 2024

Molecularly imprinted polymers (MIPs) function as synthetic analogues of antibody–antigen systems that provide molecular recognition. In combination with an electrochemical interface, MIPs afford a promising route to selectively detect diverse range chemical analytes and environmental contaminants (e.g., per- polyfluoroalkyl substances, PFAS). However, mechanical instabilities binding irreversibility may limit the practical utility field-deployable sensor. Herein, we present directed optimization MIP-based sensors for PFAS by varying key fabrication parameters (i.e., potential window, scan rate, molar ratio) modulate properties sensing reversibility, measured atomic force microscopy (AFM)-based nanoindentation methods. We demonstrate elastic recovery MIP films strongly depends on synthesis rate during anodic polymerization. Furthermore, increase in significantly improves reversibility mitigates signal drift. anticipate understanding will insights into development robust reliable monitoring.

Language: Английский

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