Recent progress of antibacterial strategy for 3D-printed bone repair scaffold DOI
Xiaojie Chen, Xinyu Li, Qing Li

et al.

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: 66, P. 106601 - 106601

Published: April 30, 2025

Language: Английский

Multifunctional Hydrogel Microneedles (HMNs) in Drug Delivery and Diagnostics DOI Creative Commons
Hossein Omidian, Sumana Dey Chowdhury

Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 206 - 206

Published: March 15, 2025

Hydrogel microneedles (HMNs) have emerged as a transformative platform for minimally invasive drug delivery and biosensing, offering enhanced bioavailability, controlled release, real-time biomarker detection. By leveraging swelling hydrogels, nanomaterial integration, stimuli-responsive properties, HMNs provide precision medicine capabilities across diverse therapeutic diagnostic applications. However, challenges remain in mechanical stability, hydrogel-based MNs must balance flexibility with sufficient strength skin penetration. Drug retention release require optimization to prevent premature diffusion ensure sustained effects. Additionally, biosensing accuracy is influenced by variability interstitial fluid extraction signal transduction. Clinical translation hindered regulatory hurdles, scalability concerns, the need extensive safety validation human trials. This review critically examines key materials, fabrication techniques, functional testing frameworks of while addressing these limitations. Furthermore, we explore future research directions smart wearable MNs, AI-assisted hybrid drug–device platforms optimize transdermal medicine. Overcoming barriers will drive clinical adoption HMNs, paving way next-generation patient-centered therapeutics diagnostics.

Language: Английский

Citations

1
Advances in dopamine electrochemical sensors: Properties and application prospects of different modified materials DOI

Zhen-Fu Lin,

Hao Li, Zhencheng Chen

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113535 - 113535

Published: April 1, 2025

Language: Английский

Citations

0
Enhancing vascular implants with heparin-polylysine-copper nanozyme coating for synergistic anticoagulation and antirestenotic activity DOI
Zheng Zeng, Tao Liu, Pei Zeng

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143048 - 143048

Published: April 1, 2025

Language: Английский

Citations

0
Recent progress of antibacterial strategy for 3D-printed bone repair scaffold DOI
Xiaojie Chen, Xinyu Li, Qing Li

et al.

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: 66, P. 106601 - 106601

Published: April 30, 2025

Language: Английский

Citations

0